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Integrinas

Integrinas

Os inibidores de integrinas têm como alvo as integrinas, uma família de receptores de superfície celular que desempenham um papel crucial na adesão celular, migração e transdução de sinais. As integrinas estão envolvidas na regulação do ciclo celular, particularmente em processos como divisão e diferenciação celular. Inibir integrinas pode interromper esses processos, levando à parada do ciclo celular e apoptose, tornando esses inibidores valiosos na pesquisa do câncer e no estudo da metástase. Na CymitQuimica, oferecemos uma ampla gama de inibidores de integrinas de alta qualidade para apoiar sua pesquisa em regulação do ciclo celular, biologia do câncer e desenvolvimento terapêutico.

Foram encontrados 224 produtos de "Integrinas"

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  • A-205804

    CAS:
    <p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>
    Fórmula:C15H12N2OS2
    Pureza:98.07% - 98.52%
    Cor e Forma:Solid
    Peso molecular:300.4
  • Cyclo(-RGDfK)

    CAS:
    <p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>
    Fórmula:C27H41N9O7
    Pureza:95.29% - >99.99%
    Cor e Forma:Solid
    Peso molecular:603.67
  • PND-1186

    CAS:
    <p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>
    Fórmula:C25H26F3N5O3
    Pureza:99.14% - 99.75%
    Cor e Forma:Solid
    Peso molecular:501.5
  • GLPG0187

    CAS:
    <p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>
    Fórmula:C29H37N7O5S
    Pureza:99.4% - 99.70%
    Cor e Forma:Solid
    Peso molecular:595.71
  • OSU-T315

    CAS:
    <p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>
    Fórmula:C30H30F3N5O
    Pureza:98.69%
    Cor e Forma:Solid
    Peso molecular:533.59
  • Arginine-glycine-aspartic acid

    CAS:
    <p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>
    Fórmula:C12H22N6O6
    Pureza:99.11%
    Cor e Forma:Solid
    Peso molecular:346.34
  • Cyclo(RADfK)

    CAS:
    <p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>
    Fórmula:C28H43N9O7
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:617.7
  • Cyclo(-RGDfK) TFA

    CAS:
    <p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>
    Fórmula:C29H42F3N9O9
    Pureza:98.99% - 99.54%
    Cor e Forma:Solid
    Peso molecular:717.69
  • CWHM-12

    CAS:
    <p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>
    Fórmula:C26H32BrN5O6
    Pureza:98.05% - 99.83%
    Cor e Forma:Solid
    Peso molecular:590.47
  • H-Gly-Arg-Gly-Asp-Asn-Pro-OH

    CAS:
    <p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>
    Fórmula:C23H38N10O10
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:614.61
  • iRGD peptide

    CAS:
    <p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>
    Fórmula:C35H57N13O14S2
    Pureza:98.77%
    Cor e Forma:Solid
    Peso molecular:948.04
  • Leukadherin-1

    CAS:
    <p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>
    Fórmula:C22H15NO4S2
    Pureza:98.49% - 98.93%
    Cor e Forma:Solid
    Peso molecular:421.49
  • Pyrintegrin

    CAS:
    <p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>
    Fórmula:C23H25N5O3S
    Pureza:99.19%
    Cor e Forma:Solid
    Peso molecular:451.54
  • Orbofiban

    CAS:
    <p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>
    Fórmula:C17H23N5O4
    Cor e Forma:Solid
    Peso molecular:361.4
  • Cucurbitacin B

    CAS:
    <p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>
    Fórmula:C32H46O8
    Pureza:97.1% - 99.33%
    Cor e Forma:Solid
    Peso molecular:558.7
  • ILK-IN-2

    CAS:
    <p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>
    Fórmula:C30H30F3N5O
    Pureza:99.30%
    Cor e Forma:Solid
    Peso molecular:533.59
  • A-286982

    CAS:
    <p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>
    Fórmula:C24H27N3O4S
    Pureza:97.81%
    Cor e Forma:Solid
    Peso molecular:453.55
  • Arg-Gly-Asp TFA (99896-85-2(free base))


    <p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>
    Fórmula:C14H23F3N6O8
    Pureza:99.2% - ≥98%
    Cor e Forma:Solid
    Peso molecular:460.36
  • roxifiban

    CAS:
    <p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>
    Fórmula:C21H29N5O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:447.48
  • LXW7

    CAS:
    <p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>
    Fórmula:C29H48N12O12S2
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:820.89
  • Natalizumab

    CAS:
    <p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>
    Pureza:98.00%
    Cor e Forma:Liquid
    Peso molecular:N/A
  • Lifitegrast

    CAS:
    <p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>
    Fórmula:C29H24Cl2N2O7S
    Pureza:99.39% - 99.66%
    Cor e Forma:Solid
    Peso molecular:615.48
  • Irigenin

    CAS:
    <p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>
    Fórmula:C18H16O8
    Pureza:99.50% - 99.85%
    Cor e Forma:Solid
    Peso molecular:360.31
  • Carotegrast methyl

    CAS:
    <p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>
    Fórmula:C28H26Cl2N4O5
    Pureza:99.26% - 99.72%
    Cor e Forma:Solid
    Peso molecular:569.44
  • Tirofiban hydrochloride monohydrate

    CAS:
    <p>Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>
    Fórmula:C22H39ClN2O6S
    Pureza:98.81% - >99.99%
    Cor e Forma:White Solid
    Peso molecular:495.07
  • E7820

    CAS:
    <p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>
    Fórmula:C17H12N4O2S
    Pureza:98.31% - 99.11%
    Cor e Forma:Solid
    Peso molecular:336.37
  • ILK-IN-3

    CAS:
    <p>ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.</p>
    Fórmula:C10H12N6O
    Pureza:99.69%
    Cor e Forma:Solid
    Peso molecular:232.24
  • Cyclo(RGDyK) trifluoroacetate

    CAS:
    <p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>
    Fórmula:C31H43F6N9O12
    Pureza:95.28% - ≥95%
    Cor e Forma:Solid
    Peso molecular:847.72
  • TR-14035

    CAS:
    <p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>
    Fórmula:C24H21Cl2NO5
    Pureza:98.98%
    Cor e Forma:Solid
    Peso molecular:474.33
  • BIO-1211

    CAS:
    <p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>
    Fórmula:C36H48N6O9
    Pureza:99.33%
    Cor e Forma:Solid
    Peso molecular:708.8
  • Eptifibatide acetate (148031-34-9 free base)

    CAS:
    <p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>
    Fórmula:C35H49N11O9S2·xC2H4O2
    Pureza:99.7% - 99.87%
    Cor e Forma:Solid
    Peso molecular:831.96 (free base)
  • GPRP acetate (67869-62-9 free base)

    CAS:
    <p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>
    Fórmula:C20H35N7O7
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:485.53
  • Bexotegrast

    CAS:
    <p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>
    Fórmula:C27H36N6O3
    Pureza:99.53%
    Cor e Forma:Solid
    Peso molecular:492.61
  • Etaracizumab

    CAS:
    <p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>
    Pureza:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)
    Cor e Forma:Liquid
    Peso molecular:144.3 (kDa)
  • Muromonab

    CAS:
    <p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>
    Pureza:95% - 97.51% (SEC-HPLC)
    Cor e Forma:Liquid
  • RO0270608

    CAS:
    <p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>
    Fórmula:C24H19Cl3N2O4
    Pureza:98.26%
    Cor e Forma:Solid
    Peso molecular:505.78
  • Voxalatamab

    CAS:
    <p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>
    Cor e Forma:Liquid
  • Rovelizumab

    CAS:
    <p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>
    Cor e Forma:Liquid
  • Vepsitamab

    CAS:
    <p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>
    Cor e Forma:Liquid
  • Cevostamab

    CAS:
    <p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>
    Cor e Forma:Liquid
  • Pavurutamab

    CAS:
    <p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>
    Cor e Forma:Liquid
  • Enlimomab

    CAS:
    <p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>
    Cor e Forma:Liquid
  • Anti-Mouse IL-1a Antibody (ALF-161)


    <p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>
    Pureza:98%
    Cor e Forma:Odour Liquid
  • Pasotuxizumab

    CAS:
    <p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA &amp; CD3 with K D s 47.0 &amp; 9.4 nM, for mCRPC research.</p>
    Cor e Forma:Liquid
  • Ubamatamab

    CAS:
    <p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>
    Cor e Forma:Liquid
  • Vatelizumab

    CAS:
    <p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>
    Pureza:95%
    Cor e Forma:Liquid
  • Tepoditamab

    CAS:
    <p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>
    Cor e Forma:Liquid
  • Vonsetamig

    CAS:
    <p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>
    Cor e Forma:Liquid
  • Flotetuzumab

    CAS:
    <p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>
    Cor e Forma:Liquid
  • Linvoseltamab

    CAS:
    <p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>
    Cor e Forma:Liquid
  • Vibecotamab

    CAS:
    <p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>
    Cor e Forma:Liquid
  • Obrindatamab

    CAS:
    <p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>
    Cor e Forma:Liquid
  • Pacanalotamab

    CAS:
    <p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>
    Cor e Forma:Liquid
  • OS-2966


    <p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>
    Pureza:95%
    Cor e Forma:Odour Liquid
  • Anti-Mouse CD3ε Antibody (145-2C11)


    <p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>
    Pureza:99%
    Cor e Forma:Odour Liquid
  • Gresonitamab

    CAS:
    <p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>
    Cor e Forma:Liquid
  • SB273005

    CAS:
    <p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>
    Fórmula:C22H24F3N3O4
    Pureza:99.58%
    Cor e Forma:Solid
    Peso molecular:451.44
  • Tirofiban

    CAS:
    <p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>
    Fórmula:C22H36N2O5S
    Pureza:99.83%
    Cor e Forma:Solid
    Peso molecular:440.6
  • GR 144053 trihydrochloride

    CAS:
    <p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>
    Fórmula:C18H30Cl3N5O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:454.82
  • Sibrafiban

    CAS:
    <p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>
    Fórmula:C20H28N4O6
    Cor e Forma:Solid
    Peso molecular:420.46
  • UR-3216

    CAS:
    <p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>
    Fórmula:C27H29N7O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:563.56
  • L 703014

    CAS:
    <p>L 703014 is an antagonist of the fibrinogen receptor.</p>
    Fórmula:C24H34N4O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:442.55
  • Balamapimod

    CAS:
    <p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>
    Fórmula:C30H32ClN7OS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:574.14
  • BMS-587101

    CAS:
    <p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>
    Fórmula:C26H20Cl2N4O4S
    Cor e Forma:Solid
    Peso molecular:555.43
  • BMS-688521

    CAS:
    <p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>
    Fórmula:C26H19Cl2N5O4
    Pureza:98.87%
    Cor e Forma:Solid
    Peso molecular:536.37
  • MK-0668

    CAS:
    <p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>
    Fórmula:C31H30Cl2N6O6S
    Cor e Forma:Solid
    Peso molecular:685.58
  • NSC47924

    CAS:
    <p>NSC47924 is a laminin receptor (LR) inhibitor.</p>
    Fórmula:C18H17NO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:279.33
  • Zalunfiban

    CAS:
    <p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>
    Fórmula:C16H18N8O2S
    Cor e Forma:Solid
    Peso molecular:386.43
  • TCS 2314

    CAS:
    <p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>
    Fórmula:C28H34N4O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:522.59
  • Chrysotobibenzyl

    CAS:
    <p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>
    Fórmula:C19H24O5
    Cor e Forma:Solid
    Peso molecular:332.39
  • αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)


    <p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>
    Fórmula:C28H35F3N6O8S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:672.67
  • Zaurategrast ethyl ester sulfate

    CAS:
    <p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>
    Fórmula:C56H60Br2N8O10S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1197.01
  • RUC-1

    CAS:
    <p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>
    Fórmula:C11H15N5OS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:265.33
  • Zaurategrast ethyl ester

    CAS:
    <p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>
    Fórmula:C28H29BrN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:549.46
  • IMB-10

    CAS:
    <p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>
    Fórmula:C19H15NOS2
    Cor e Forma:Solid
    Peso molecular:337.46
  • Ro 43-5054

    CAS:
    <p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>
    Fórmula:C24H27N5O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:497.5
  • BOP sodium

    CAS:
    <p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>
    Fórmula:C25H29N3NaO7S
    Cor e Forma:Solid
    Peso molecular:538.57
  • GSK-3008348

    CAS:
    <p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>
    Fórmula:C29H37N5O2
    Pureza:99.547%
    Cor e Forma:Solid
    Peso molecular:487.64
  • Valategrast

    CAS:
    <p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>
    Fórmula:C30H32Cl3N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:604.95
  • Valategrast hydrochloride

    CAS:
    <p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>
    Fórmula:C30H33Cl4N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:641.41
  • CLT-28643

    CAS:
    <p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>
    Fórmula:C19H17N3O4
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:351.36
  • Integrin-IN-2

    CAS:
    <p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>
    Fórmula:C27H30N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:458.55
  • XVA143

    CAS:
    <p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>
    Fórmula:C25H21Cl2N3O8
    Cor e Forma:Solid
    Peso molecular:562.36
  • Integrin modulator 1

    CAS:
    <p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>
    Fórmula:C13H14N2O4
    Pureza:99.61%
    Cor e Forma:Solid
    Peso molecular:262.26
  • Firategrast

    CAS:
    <p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>
    Fórmula:C27H27F2NO6
    Pureza:99.16%
    Cor e Forma:Solid
    Peso molecular:499.5
  • Elarofiban

    CAS:
    <p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>
    Fórmula:C22H32N4O4
    Pureza:98.76%
    Cor e Forma:Solid
    Peso molecular:416.51
  • 3-Hydroxyxanthone

    CAS:
    <p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>
    Fórmula:C13H8O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:212.2
  • ICAM-1-IN-1

    CAS:
    <p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>
    Fórmula:C15H11BrN2O2S
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:363.23
  • BI-1950

    CAS:
    <p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>
    Fórmula:C32H26Cl2FN7O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:646.5
  • Teclistamab

    CAS:
    <p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>
    Pureza:95%
    Cor e Forma:Liquid
  • Synstatin (92-119)

    CAS:
    <p>Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and</p>
    Fórmula:C133H207N35O46
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3032.27
  • TAK 029

    CAS:
    <p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>
    Fórmula:C19H23N5O7
    Cor e Forma:Solid
    Peso molecular:433.42
  • αvβ6 integrin inhibitor 2

    CAS:
    <p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>
    Fórmula:C21H30N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:386.49
  • Lotrafiban

    CAS:
    <p>Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.</p>
    Fórmula:C23H32N4O4
    Cor e Forma:Solid
    Peso molecular:428.52
  • JNJ-26076713

    CAS:
    <p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>
    Fórmula:C29H38N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:490.64
  • SB-267268

    CAS:
    <p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>
    Fórmula:C22H24F3N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:451.44
  • Zaurategrast

    CAS:
    <p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>
    Fórmula:C26H25BrN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:521.41
  • Solitomab

    CAS:
    <p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>
    Cor e Forma:Liquid
  • Carotegrast

    CAS:
    <p>Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.</p>
    Fórmula:C27H24Cl2N4O5
    Cor e Forma:Solid
    Peso molecular:555.41
  • Tirofiban HCl

    CAS:
    <p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>
    Fórmula:C22H37ClN2O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:477.06