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Integrinas

Integrinas

Os inibidores de integrinas têm como alvo as integrinas, uma família de receptores de superfície celular que desempenham um papel crucial na adesão celular, migração e transdução de sinais. As integrinas estão envolvidas na regulação do ciclo celular, particularmente em processos como divisão e diferenciação celular. Inibir integrinas pode interromper esses processos, levando à parada do ciclo celular e apoptose, tornando esses inibidores valiosos na pesquisa do câncer e no estudo da metástase. Na CymitQuimica, oferecemos uma ampla gama de inibidores de integrinas de alta qualidade para apoiar sua pesquisa em regulação do ciclo celular, biologia do câncer e desenvolvimento terapêutico.

Foram encontrados 256 produtos de "Integrinas"

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  • Lotrafiban hydrochloride
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    Lotrafiban hydrochloride

    CAS:
    Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.
    Fórmula:C23H33ClN4O4
    Cor e Forma:Solid
    Peso molecular:464.99

    Ref: TM-T27846

  • BI-1950
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    BI-1950

    CAS:
    BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.
    Fórmula:C32H26Cl2FN7O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:646.5

    Ref: TM-T14558

  • ATN-161
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    ATN-161

    CAS:
    ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.
    Fórmula:C23H35N9O8S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:597.64

    Ref: TM-T10398

  • αvβ1 integrin-IN-1
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    αvβ1 integrin-IN-1

    CAS:
    <p>αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.</p>
    Fórmula:C26H34N6O6S
    Pureza:99.74% - >99.99%
    Cor e Forma:Solid
    Peso molecular:558.65

    Ref: TM-T13473

  • Roxifiban acetate
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    Roxifiban acetate

    CAS:
    Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used in
    Fórmula:C23H33N5O8
    Pureza:97.91% - 98.36%
    Cor e Forma:Solid
    Peso molecular:507.54

    Ref: TM-T24733

  • L 734217
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    L 734217

    CAS:
    L 734217 is an antagonist of the fibrinogen receptor.
    Fórmula:C18H31N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:353.46

    Ref: TM-T24352

  • Des-ethyl-carafiban
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    Des-ethyl-carafiban

    CAS:
    Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.
    Fórmula:C22H23N5O5
    Cor e Forma:Solid
    Peso molecular:437.448

    Ref: TM-T206156

  • 6-B345TTQ
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    6-B345TTQ

    CAS:
    6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.
    Fórmula:C22H20BrNO4
    Cor e Forma:Solid
    Peso molecular:442.303

    Ref: TM-T204244

  • Logotipo do CymitQuimica
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    α5β1 integrin agonist-1

    CAS:
    α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.
    Fórmula:C24H26FN5O9
    Cor e Forma:Solid
    Peso molecular:547.49

    Ref: TM-T63868

  • SF0166
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    SF0166

    CAS:
    SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.
    Fórmula:C23H27F2N5O4
    Cor e Forma:Solid
    Peso molecular:475.49

    Ref: TM-T70368

  • Logotipo do CymitQuimica
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    Zalunfiban dihydrochloride

    Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.
    Fórmula:C16H20Cl2N8O2S
    Cor e Forma:Solid
    Peso molecular:459.35

    Ref: TM-T62878

  • OPN expression inhibitor 1
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    OPN expression inhibitor 1

    CAS:
    OPN expression inhibitor 1 is an osteopontin expression inhibitor used in the study of breast cancer metastasis.
    Fórmula:C25H33N3O5
    Pureza:99.78%
    Cor e Forma:Solid
    Peso molecular:455.55

    Ref: TM-T62820

  • Fradafiban
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    Fradafiban

    CAS:
    Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
    Fórmula:C20H21N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:367.40

    Ref: TM-T11322

  • GSK3335103
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    GSK3335103

    CAS:
    GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.
    Fórmula:C27H36FN3O4
    Cor e Forma:Solid
    Peso molecular:485.59

    Ref: TM-T200463

  • SR121566A
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    SR121566A

    CAS:
    SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).
    Fórmula:C20H25N5O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:431.51

    Ref: TM-T12999

  • GR 83895
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    GR 83895

    CAS:
    GR 83895 is an antagonist of prototype fibrinogen receptor.
    Fórmula:C29H39N9O8S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:673.74

    Ref: TM-T25460