Integrinas
Os inibidores de integrinas têm como alvo as integrinas, uma família de receptores de superfície celular que desempenham um papel crucial na adesão celular, migração e transdução de sinais. As integrinas estão envolvidas na regulação do ciclo celular, particularmente em processos como divisão e diferenciação celular. Inibir integrinas pode interromper esses processos, levando à parada do ciclo celular e apoptose, tornando esses inibidores valiosos na pesquisa do câncer e no estudo da metástase. Na CymitQuimica, oferecemos uma ampla gama de inibidores de integrinas de alta qualidade para apoiar sua pesquisa em regulação do ciclo celular, biologia do câncer e desenvolvimento terapêutico.
Foram encontrados 289 produtos para "Integrinas".
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BI-1950
CAS:BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.Fórmula:C32H26Cl2FN7O3Pureza:98%Cor e Forma:SolidPeso molecular:646.5Carotegrast
CAS:Carotegrast is a selective α4 integrin antagonist, blocking the interaction between α4β1/α4β7 integrins and their ligands.Fórmula:C27H24Cl2N4O5Cor e Forma:Yellow SolidPeso molecular:555.41Zaurategrast
CAS:Zaurategrast (CDP323) is an oral α4-integrin antagonist that blocks VCAM-1 interactions and is used to study immune cell trafficking.Fórmula:C26H25BrN4O3Pureza:98%Cor e Forma:Yellow SolidPeso molecular:521.41SB-267268
CAS:SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).Fórmula:C22H24F3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:451.443-Hydroxyxanthone
CAS:3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical veinFórmula:C13H8O3Pureza:98%Cor e Forma:SolidPeso molecular:212.2α7β1 integrin modulator-1
CAS:α7β1 integrin modulator-1 is an α7β1 integrin activator; upregulates α7 integrin expression and improves laminin binding for DMD research.Fórmula:C23H29N3O6SPureza:98.55%Cor e Forma:White SolidPeso molecular:475.56Synstatin (92-119)
CAS:Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFórmula:C133H207N35O46Pureza:98%Cor e Forma:SolidPeso molecular:3032.27Bexotegrast HCl
CAS:Bexotegrast (PLN-74809) inhibits αVβ1/αVβ6 integrins, preventing TGF-β1 activation to treat IPF and PSC.Fórmula:C27H38Cl2N6O3Cor e Forma:SolidPeso molecular:565.54L 738167
CAS:L 738167 is a potent antagonist of the long-acting fibrinogen receptor.Fórmula:C25H34N6O6SCor e Forma:SolidPeso molecular:546.64SC-52012
CAS:SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.Fórmula:C25H30N4O6Pureza:97.20%Cor e Forma:White SolidPeso molecular:482.53Lamifiban
CAS:Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.Fórmula:C24H28N4O6Pureza:98%Cor e Forma:SolidPeso molecular:468.5Roxifiban acetate
CAS:Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used inFórmula:C23H33N5O8Pureza:97.91% - 98.36%Cor e Forma:White SolidPeso molecular:507.54αvβ1 integrin-IN-1
CAS:αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Fórmula:C26H34N6O6SPureza:99.39% - 99.69%Cor e Forma:SolidPeso molecular:558.65Ref: TM-T13473
1mg109,00€5mg260,00€1mL*10mM (DMSO)319,00€10mg409,00€25mg660,00€50mg888,00€100mg1.224,00€200mg1.648,00€α5β1 integrin agonist-1
CAS:α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.Fórmula:C24H26FN5O9Cor e Forma:SolidPeso molecular:547.496-B345TTQ
CAS:6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.Fórmula:C22H20BrNO4Cor e Forma:SolidPeso molecular:442.303Des-ethyl-carafiban
CAS:Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.Fórmula:C22H23N5O5Cor e Forma:SolidPeso molecular:437.448OPN expression inhibitor 1
CAS:OPN expression inhibitor 1 is an osteopontin expression inhibitor used in the study of breast cancer metastasis.Fórmula:C25H33N3O5Pureza:99.78%Cor e Forma:White SolidPeso molecular:455.55Ref: TM-T62820
1mg126,00€5mg258,00€1mL*10mM (DMSO)259,00€10mg385,00€25mg695,00€50mg1.009,00€100mg1.314,00€Fradafiban
CAS:Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.Fórmula:C20H21N3O4Pureza:98%Cor e Forma:SolidPeso molecular:367.40GSK3335103
CAS:GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.Fórmula:C27H36FN3O4Cor e Forma:SolidPeso molecular:485.59EMD-132338
CAS:EMD 132338 is a GPIIb/IIIa antagonist.Fórmula:C17H23N5O4Cor e Forma:SolidPeso molecular:361.4
