Ferroptose
A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.
Foram encontrados 233 produtos de "Ferroptose"
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Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Fórmula:C12H17NO2Pureza:97.72% - 99.78%Cor e Forma:SolidPeso molecular:207.27Matrine
CAS:Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Fórmula:C15H24N2OPureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:248.36Eugenol
CAS:Eugenol (Allylguaiacol) is a Standardized Chemical Allergen.Fórmula:C10H12O2Pureza:98.03%Cor e Forma:Colorless Or Pale Yellow Liquid Pungent Taste (Ntp 1992)Peso molecular:164.20L-Glutathione reduced
CAS:L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.Fórmula:C10H17N3O6SPureza:97.37% - 99.99%Cor e Forma:SolidPeso molecular:307.32Artesunate
CAS:Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.Fórmula:C19H28O8Pureza:97.67% - 99.9%Cor e Forma:White Crystalline PowderPeso molecular:384.42Lovastatin
CAS:Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.Fórmula:C24H36O5Pureza:99.66% - 99.92%Cor e Forma:The Substance Is A White-Yellowish To Yellow Powder Solid PowderPeso molecular:404.54Simvastatin
CAS:Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Fórmula:C25H38O5Pureza:98.54% - 99.13%Cor e Forma:SolidPeso molecular:418.57Ref: TM-T0687
10mg40,00€1mL*10mM (DMSO)44,00€25mg55,00€50mg65,00€100mg101,00€200mg133,00€500mg256,00€Linagliptin
CAS:Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Fórmula:C25H28N8O2Pureza:99.15% - >99.99%Cor e Forma:SolidPeso molecular:472.54Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Fórmula:C18H14N4O5SPureza:98.00% - 99.28%Cor e Forma:Minute Brownish-Yellow CrystalsPeso molecular:398.39Pravastatin sodium
CAS:Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Fórmula:C23H35NaO7Pureza:97.14% - 99.97%Cor e Forma:White Crystalline PowderPeso molecular:446.52Vildagliptin
CAS:Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.Fórmula:C17H25N3O2Pureza:97.81% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:303.40Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Fórmula:C21H16ClF3N4O3Pureza:98% - 99.89%Cor e Forma:SolidPeso molecular:464.82Curcumin
CAS:Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Fórmula:C21H20O6Pureza:95% - 98.98%Cor e Forma:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Peso molecular:368.38Imidazole ketone erastin
CAS:View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.Fórmula:C35H35ClN6O5Pureza:98.48% - 99.87%Cor e Forma:SolidPeso molecular:655.14Ref: TM-T5523
1mg66,00€2mg92,00€5mg144,00€1mL*10mM (DMSO)161,00€10mg185,00€25mg318,00€50mg485,00€100mg640,00€FSEN1
CAS:FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.Fórmula:C22H22BrN5OSPureza:99.54% - 99.97%Cor e Forma:SolidPeso molecular:484.41Butylated hydroxytoluene
CAS:Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.Fórmula:C15H24OPureza:99.72%Cor e Forma:Colourless Solid PowderPeso molecular:220.35Acetylcysteine
CAS:Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.Fórmula:C5H9NO3SPureza:98.01% - >99.99%Cor e Forma:Crystals From Water SolidPeso molecular:163.19Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:Light Yellow Solid PowderPeso molecular:433.45Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Fórmula:C11H12N2O2SPureza:98.72% - 99.43%Cor e Forma:Crystalline SolidPeso molecular:236.29
