CAS 458-37-7

Curcumina

Descrição:

Curcumina, com o número CAS 458-37-7, é um composto polifenólico natural derivado principalmente do rizoma da planta de cúrcuma (Curcuma longa). É conhecido por sua vibrante cor amarela e é amplamente reconhecido por seus potenciais benefícios à saúde, incluindo propriedades anti-inflamatórias, antioxidantes e anticancerígenas. Curcumina exibe uma estrutura química complexa, caracterizada por seus grupos diketona e fenólico, que contribuem para sua reatividade e atividade biológica. É pouco solúvel em água, mas solúvel em solventes orgânicos, o que pode afetar sua biodisponibilidade em aplicações terapêuticas. Curcumina tem sido objeto de extensa pesquisa, explorando seu papel em várias condições de saúde, incluindo doenças crônicas e distúrbios metabólicos. Além disso, foi estudado por seu uso potencial em corantes alimentares e como suplemento dietético. No entanto, sua estabilidade pode ser influenciada por fatores como pH e exposição à luz, que são considerações importantes tanto na pesquisa quanto nas aplicações práticas.

Fórmula: C₂₁H₂₀O₆

InChI: InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

Chave InChI: InChIKey=VFLDPWHFBUODDF-FCXRPNKRSA-N

SMILES: C(=C/C(CC(/C=C/C1=CC(OC)=C(O)C=C1)=O)=O)\C2=CC(OC)=C(O)C=C2

Sinónimos:

• (1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one
• (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
• (E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
• (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadien-3,5-dione
• (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
• 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-
• 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E,E)-
• 1,7-Bis(4-Hidroxi-3-Metoxifenil)Hepta-1,6-Dieno-3,5-Diona
• 1,7-Bis(4-Hydroxy-3-Methoxyphenyl)-1,6-Heptadiene-3,5-Dione
• 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-dien-3,5-dion
• 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
• Biocurcumax
• Br 213
• C Yellow 15
• Colorant E 100
• Curcuma
• Curcuma yellow
• Curcumax
• Curcumin I
• Curcumin W
• Curcumine
• Cureit
• Curouma
• Diferuloylmethane
• E 100 (dye)
• E-100
• E100
• Gelbwurz
• Haidr
• Halad
• Haldar
• Halud
• Hepta-1,6-Diene-3,5-Dione, 1,7-Bis(4-Hydroxy-3-Methoxyphenyl)- (1E,6E)
• INS 100i
• Indian Saffron
• Jianghuangsu
• Kacha Haldi
• Kachs Haldi
• Kiriyasu Oil Yellow U
• Lipocurc
• Longvida
• Merita Earth
• NanoCurc
• Natural Yellow 3
• Natxtra
• Nsc 32982
• Safra D'Inde
• San-Ei Curcumine AL
• San-Ei Gen Curcumine AL
• Souchet
• Terra Merita
• Theracurmin
• Theracurmin CR 011L
• Tumeric Yellow
• Turmeric
• Turmeric (dye)
• Turmeric yellow
• Ukon
• Ukon (dye)
• Vacurin
• Yellow Ginger
• Yellow Root
• Yo-Kin
• trans,trans-Curcumin
• C.I. 75300
• C.I. 75300
• C.I. Natural Yellow 3
• Curcumin

Curcumin (Synthetic)

CAS: 458-37-7

Fórmula: C₂₁H₂₀O₆

Pureza: >97.0%(T)

Cor e Forma: Light yellow to Brown powder to crystal

Peso molecular: 368.39

Ref: 3B-C2302

Curcumin (Natural)

CAS: 458-37-7

Fórmula: C₂₁H₂₀O₆

Cor e Forma: Light yellow to Brown powder to crystal

Peso molecular: 368.39

Ref: 3B-C0434

Curcumin, 95% (total curcuminoid content), from Turmeric rhizome

CAS: 458-37-7

Curcumin is used for boron quantification. It inhibits lipoxygenase and cyclooxygenase. It acts as a dietary supplement and is used in pharmaceutical industry. It acts as a food coloring agent and acts as a food additive. This Thermo Scientific Chemicals brand product was originally part of the Alfa

Fórmula: C₂₁H₂₀O₆

Pureza: 95%

Cor e Forma: Orange-yellow or orange, Powder or crystalline powder

Peso molecular: 368.39

Ref: 02-B21573

Curcumin

CAS: 458-37-7

Curcumin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₂₁H₂₀O₆

Pureza: (HPLC) ≥98%

Cor e Forma: Powder

Peso molecular: 368.39

Ref: 11-4739S

Curcumin

CAS: 458-37-7

Fórmula: [HOC6H3(OCH3)CH=CHCO]2CH2

Pureza: ≥65% (HPLC)

Cor e Forma: powder

Peso molecular: 368.38

Ref: 23-C1386

Curcumin

CAS: 458-37-7

Coloring matter of vegetable or animal origin

Fórmula: C₂₁H₂₀O₆

Cor e Forma: Orange Yellow Powder

Peso molecular: 368.12599

Ref: 45-1151855

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

CAS: 458-37-7

Fórmula: C₂₁H₂₀O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 368.3799

Ref: IN-DA0038PG

Curcumin

CAS: 458-37-7

Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.

Fórmula: C₂₁H₂₀O₆

Pureza: 95% - 99.91%

Cor e Forma: Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)

Peso molecular: 368.38

Ref: TM-T1516

Curcumin

CAS: 458-37-7

Curcumin

Fórmula: C₂₁H₂₀O₆

Pureza: 97%

Cor e Forma: Solid-Powder

Peso molecular: 368.3799

Ref: 54-BIC8500

Curcumin, pure, 98%

CAS: 458-37-7

Fórmula: C₂₁H₂₀O₆

Pureza: (HPLC) ≥ 98.0%

Cor e Forma: Yellow or orange powder

Peso molecular: 368.39

Ref: 7W-GP7022

Curcumin

CAS: 458-37-7

Fórmula: C₂₁H₂₀O₆

Cor e Forma: Orange Solid

Peso molecular: 368.39

Ref: 4Z-C-691

Curcumin

CAS: 458-37-7

Fórmula: C₂₁H₂₀O₆

Cor e Forma: Yellow or orange powder

Peso molecular: 368.39

Ref: 7W-GP8291

Curcumin (0.1% in ca. 95% Ethanol)

CAS: 458-37-7

Cor e Forma: Light yellow to Brown clear liquid

Ref: 3B-C0435

Curcumin

CAS: 458-37-7

Fórmula: C₂₁H₂₀O₆

Cor e Forma: Neat

Peso molecular: 368.38

Ref: 04-C11780000

Curcumin (Standard)

CAS: 458-37-7

Curcumin (Standard) is a reference standard for research and analysis in studies involving Curcumin. Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide range of pharmacological activities such as antitumor, anti-inflammatory and antioxidant.

Fórmula: C₂₁H₂₀O₆

Cor e Forma: Solid

Peso molecular: 368.38

Ref: TM-TMSM-2122

Curcumin

CAS: 458-37-7

Curcumin, a polyphenolic compound derived from dietary spice turmeric, possesses diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities, it has effective activity against including cancer, cardio-

Fórmula: C₂₁H₂₀O₆

Pureza: 95%~99%

Cor e Forma: Orange powder

Peso molecular: 368.385

Ref: BP-BP0421

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

CAS: 458-37-7

Fórmula: C₂₁H₂₀O₆

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 368.385

Ref: 10-F358294

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

CAS: 458-37-7

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

Fórmula: C₂₁H₂₀O₆

Pureza: 96%

Cor e Forma: Orange Solid-Powder

Peso molecular: 368.3799

Ref: 54-OR24598

Curcumin

CAS: 458-37-7

Ketone phenol

Fórmula: C₂₁H₂₀O₆

Pureza: ≥ 98.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 368.39

Ref: 5G-89180

Curcumin

CAS: 458-37-7

Applications A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disease. Neuroprotective. Dyes and metabolites.
References Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), Tu, B., et al.: J .Cell Biol., 164, 341 (2004), Xu, G., et al.: Biochemistry, 44, 9817 (2005), Johnson, J., et al.: Cancer Lett., 255, 170 (2007), Chem. and Eng. News 90(31), 44 (2012)

Fórmula: C₂₁H₂₀O₆

Cor e Forma: Neat

Peso molecular: 368.38

Ref: TR-C838500