Microtúbulo associado
Os inibidores de proteínas associadas aos microtúbulos têm como alvo as proteínas que interagem com os microtúbulos, os componentes estruturais do citoesqueleto da célula que são essenciais para a divisão celular. Essas proteínas regulam a estabilidade e a dinâmica dos microtúbulos durante a mitose. A inibição de proteínas associadas aos microtúbulos pode interromper a função dos microtúbulos, levando à parada do ciclo celular e à apoptose, especialmente em células cancerígenas de rápida divisão. Esses inibidores são amplamente utilizados na pesquisa do câncer e no desenvolvimento de medicamentos. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteínas associadas aos microtúbulos de alta qualidade para apoiar sua pesquisa em divisão celular, dinâmica do citoesqueleto e terapia do câncer.
Foram encontrados 262 produtos de "Microtúbulo associado"
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Albendazole sulfoxide
CAS:Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Fórmula:C12H15N3O3SPureza:97.29%Cor e Forma:White To Off-White PowderPeso molecular:281.33Valecobulin
CAS:Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.Fórmula:C26H28N6O5SPureza:98%Cor e Forma:SolidPeso molecular:536.6Suprafenacine
CAS:<p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>Fórmula:C16H18N4OPureza:99.91%Cor e Forma:SolidPeso molecular:282.34Tau protein (592-597), Human TFA
<p>Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.</p>Fórmula:C36H63F3N10O11Pureza:>99.99%Cor e Forma:SolidPeso molecular:868.94Vindesine sulfate
CAS:<p>Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.</p>Fórmula:C43H57N5O11SPureza:97.51%Cor e Forma:Amorphous SolidPeso molecular:852Curvulin
CAS:<p>Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.</p>Fórmula:C12H14O5Pureza:98.65%Cor e Forma:SolidPeso molecular:238.24Clanfenur
CAS:<p>Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.</p>Fórmula:C16H15ClFN3O2Pureza:99.93%Cor e Forma:SolidPeso molecular:335.764-Isopropoxybenzoic acid
CAS:<p>4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.</p>Fórmula:C10H12O3Pureza:99.88%Cor e Forma:White To Off-White PowderPeso molecular:180.2TN-16
CAS:<p>TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)</p>Fórmula:C19H18N2O2Pureza:99.54%Cor e Forma:SolidPeso molecular:306.36Spastazoline
CAS:<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Fórmula:C20H30N8Pureza:99.23%Cor e Forma:SolidPeso molecular:382.51NQTrp
CAS:<p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>Fórmula:C21H16N2O4Pureza:98.35%Cor e Forma:SolidPeso molecular:360.36Gosuranemab
CAS:<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Pureza:95% - 95%Cor e Forma:LiquidST-401
CAS:<p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>Fórmula:C24H20N2OCor e Forma:SolidPeso molecular:352.43Posdinemab
CAS:<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Cor e Forma:LiquidSemorinemab
CAS:<p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>Pureza:95% - 95%Cor e Forma:Liquid4-Desacetylvinblastine hydrazide
CAS:<p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>Fórmula:C43H56N6O7Cor e Forma:SolidPeso molecular:768.94Tubulin polymerization-IN-2
CAS:<p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>Fórmula:C17H12F2N2O2Cor e Forma:SolidPeso molecular:314.29Auristatin F
CAS:<p>Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.</p>Fórmula:C40H67N5O8Pureza:98.41% - 99.25%Cor e Forma:SolidPeso molecular:745.99Sabeluzole
CAS:<p>Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.</p>Fórmula:C22H26FN3O2SPureza:98.51%Cor e Forma:SolidPeso molecular:415.52AM-5308
CAS:<p>AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.</p>Fórmula:C26H35N5O5SPureza:98.06% - 99.58%Cor e Forma:SolidPeso molecular:529.65Tau protein aggregation-IN-1
CAS:<p>Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders</p>Fórmula:C17H11BrN2O2Cor e Forma:SolidPeso molecular:355.19OSIP-486823
CAS:<p>OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.</p>Fórmula:C29H28FNO4Pureza:98.59%Cor e Forma:SolidPeso molecular:473.54IQTub4P
CAS:<p>IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).</p>Fórmula:C19H18NNa2O8PCor e Forma:SolidPeso molecular:465.305Tubulin polymerization-IN-42
CAS:<p>Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].</p>Fórmula:C22H21NO5Cor e Forma:SolidPeso molecular:379.41Alyssin
CAS:<p>Alyssin: sulforaphane analog, antioxidant; boosts Nrf2 and phase II enzymes in cancer cells; lowers PAH metabolism, reducing cancer risk in vitro.</p>Fórmula:C7H13NOS2Pureza:98%Cor e Forma:SolidPeso molecular:191.31Tubulozole
CAS:<p>Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.</p>Fórmula:C23H23Cl2N3O4SPureza:98%Cor e Forma:SolidPeso molecular:508.42Sirt1/2-IN-1
CAS:<p>Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.</p>Fórmula:C22H13ClN2OS2Cor e Forma:SolidPeso molecular:420.93Amphethinile
CAS:<p>Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.</p>Fórmula:C15H11N3SPureza:98%Cor e Forma:SolidPeso molecular:265.33Microtubule inhibitor 3
CAS:<p>Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.</p>Fórmula:C26H23FN4O3Cor e Forma:SolidPeso molecular:458.48Microtubule inhibitor 1
CAS:<p>Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).</p>Fórmula:C21H19NO3Pureza:98%Cor e Forma:SolidPeso molecular:333.38Anticancer agent 48
CAS:<p>Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.</p>Fórmula:C26H25N3O4Cor e Forma:SolidPeso molecular:443.49Tubulin polymerization-IN-39
<p>Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.</p>Fórmula:C21H21N5O5Cor e Forma:SolidPeso molecular:423.42Tubulin inhibitor 28
CAS:<p>Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.</p>Fórmula:C12H8Br2S2Cor e Forma:SolidPeso molecular:376.13Tubulin inhibitor 7
CAS:<p>Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (</p>Fórmula:C21H14N2O4Pureza:98%Cor e Forma:SolidPeso molecular:358.35MT-7
CAS:<p>MT-7 is a tubulin polymerization inhibitor.</p>Fórmula:C22H17N3O2Pureza:98%Cor e Forma:SolidPeso molecular:355.39Anticancer agent 49
CAS:<p>Anticancer agent 49, also 69, hinders cell growth and microtubule aggregation, with potential in solid and blood cancer research.</p>Fórmula:C26H25N3O4Cor e Forma:SolidPeso molecular:443.49Tubulin polymerization-IN-19
CAS:<p>Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.</p>Fórmula:C25H25NO5Cor e Forma:SolidPeso molecular:419.47DJ101
CAS:<p>DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.</p>Fórmula:C23H20N4O3Pureza:98%Cor e Forma:SolidPeso molecular:400.43Tubulin polymerization-IN-27
CAS:<p>Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.</p>Fórmula:C22H20N2O2Cor e Forma:SolidPeso molecular:344.41Aha1/Hsp90-IN-1
CAS:<p>Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.</p>Fórmula:C22H17F3N4O2Cor e Forma:SolidPeso molecular:426.39MG-2119
CAS:<p>MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.</p>Fórmula:C27H29N5O4Cor e Forma:SolidPeso molecular:487.55isoCA-4
CAS:<p>isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].</p>Fórmula:C18H20O5Cor e Forma:SolidPeso molecular:316.35Tubulin polymerization-IN-29
CAS:<p>Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.</p>Fórmula:C25H20FNO6Cor e Forma:SolidPeso molecular:449.43BNC105P
CAS:<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Fórmula:C20H21O10PCor e Forma:SolidPeso molecular:452.3485Microtubule inhibitor 4
CAS:<p>Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).</p>Fórmula:C25H23FN4O3Cor e Forma:SolidPeso molecular:446.47Tubulin inhibitor 27
CAS:<p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>Fórmula:C21H19NO4Cor e Forma:SolidPeso molecular:349.38Tubulin polymerization-IN-21
CAS:<p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>Fórmula:C30H29NO7Cor e Forma:SolidPeso molecular:515.55Tubulin polymerization-IN-10
CAS:<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Fórmula:C18H21NO6SCor e Forma:SolidPeso molecular:379.43Neuroinflammatory-IN-3
CAS:<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Fórmula:C19H19ClO3Cor e Forma:SolidPeso molecular:330.81Tubulin polymerization-IN-36
CAS:<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Fórmula:C18H18N2O3Cor e Forma:SolidPeso molecular:310.35Tubulin polymerization-IN-16
CAS:<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Fórmula:C24H27N5O5Cor e Forma:SolidPeso molecular:465.5O-GlcNAcase-IN-4
CAS:<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Fórmula:C16H22FN5O3SCor e Forma:SolidPeso molecular:383.44Tubulin polymerization-IN-18
CAS:Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.Fórmula:C25H25NO6Cor e Forma:SolidPeso molecular:435.47Synstab A
CAS:<p>Synstab A is a microtubule stabilizer.</p>Fórmula:C15H13BrCl3N3O3SCor e Forma:SolidPeso molecular:501.61Microtubule inhibitor 7
CAS:<p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>Fórmula:C25H19FN2O5Cor e Forma:SolidPeso molecular:446.43(S)-Dolaphenine hydrochloride
CAS:<p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>Fórmula:C11H13ClN2SPureza:98%Cor e Forma:SolidPeso molecular:240.75Deox B 7,4
CAS:<p>Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.</p>Fórmula:C18H18O5Cor e Forma:SolidPeso molecular:314.33Tubulin polymerization-IN-30
CAS:<p>Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.</p>Fórmula:C22H25N5O3Cor e Forma:SolidPeso molecular:407.47Tubulin inhibitor 29
CAS:<p>Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.</p>Fórmula:C12H8F2O2S2Cor e Forma:SolidPeso molecular:286.32Microtubule inhibitor 6
CAS:<p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>Fórmula:C24H19FN2O5Cor e Forma:SolidPeso molecular:434.42Tubulin inhibitor 31
<p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>Fórmula:C22H19NO2Cor e Forma:SolidPeso molecular:329.39Tubulin polymerization-IN-7
CAS:<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Fórmula:C28H24N4O6SCor e Forma:SolidPeso molecular:544.58Anticancer agent 60
CAS:<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Fórmula:C27H33N5O4SCor e Forma:SolidPeso molecular:523.65SB26019
CAS:<p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>Fórmula:C24H20O4Cor e Forma:SolidPeso molecular:372.41AMXI-5001
CAS:<p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>Fórmula:C25H20FN5O3Cor e Forma:SolidPeso molecular:457.46Tubulin inhibitor 20
CAS:<p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>Fórmula:C19H18O4Cor e Forma:SolidPeso molecular:310.34Tubulin inhibitor 26
CAS:<p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>Fórmula:C17H19N3O3Cor e Forma:SolidPeso molecular:313.35Microtubule inhibitor 5
CAS:<p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>Fórmula:C22H15FN2O4Cor e Forma:SolidPeso molecular:390.36Tubulin polymerization-IN-37
CAS:<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Fórmula:C19H20N2O4Cor e Forma:SolidPeso molecular:340.37THK-5117
CAS:<p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>Fórmula:C19H19FN2O2Cor e Forma:SolidPeso molecular:326.36OXi8007
CAS:<p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>Fórmula:C26H24NNa2O10PCor e Forma:SolidPeso molecular:587.428Hydromethylthionine HBr
CAS:<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Fórmula:C16H21Br2N3SCor e Forma:SolidPeso molecular:447.233(R)-TTBK1-IN-1
CAS:<p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.</p>Fórmula:C18H19N5O2Cor e Forma:SolidPeso molecular:337.38Tubulin polymerization-IN-25
CAS:<p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>Fórmula:C24H18N2O3SCor e Forma:SolidPeso molecular:414.48Tubulin polymerization-IN-15
CAS:<p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>Fórmula:C18H17N3O4Cor e Forma:SolidPeso molecular:339.35Tubulin polymerization-IN-20
CAS:<p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>Fórmula:C25H24FNO5Cor e Forma:SolidPeso molecular:437.46Tubulin inhibitor 18
CAS:<p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>Fórmula:C22H26O5Cor e Forma:SolidPeso molecular:370.44Tubulin/MMP-IN-1
<p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>Fórmula:C38H44NO9PCor e Forma:SolidPeso molecular:689.73Tubulin inhibitor 12
CAS:<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Fórmula:C24H20N2OCor e Forma:SolidPeso molecular:352.43Tau tracer 1
CAS:<p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>Fórmula:C34H23N5O2Cor e Forma:SolidPeso molecular:533.591Iso-Fludelone
CAS:<p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>Fórmula:C27H36F3NO6Cor e Forma:SolidPeso molecular:527.57Antitumor agent-68
CAS:<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Fórmula:C17H11NO2Cor e Forma:SolidPeso molecular:261.27Antitumor agent-71
CAS:<p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>Fórmula:C26H31N5O4SCor e Forma:SolidPeso molecular:509.62IDT
CAS:<p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>Fórmula:C8H5NS2Pureza:98%Cor e Forma:SolidPeso molecular:179.26DHNQ
CAS:<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Fórmula:C18H14N2OCor e Forma:SolidPeso molecular:274.32D011-2120
CAS:<p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>Fórmula:C17H15NO3Pureza:98%Cor e Forma:SolidPeso molecular:281.31DAT1
CAS:<p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>Fórmula:C17H15N3O2SPureza:98%Cor e Forma:SolidPeso molecular:325.38Acodazole
CAS:<p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>Fórmula:C20H19N5OPureza:98%Cor e Forma:SolidPeso molecular:345.4Acodazole hydrochloride
CAS:<p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>Fórmula:C20H20ClN5OPureza:98%Cor e Forma:SolidPeso molecular:381.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Fórmula:C15H11FN4OSPureza:98%Cor e Forma:SolidPeso molecular:314.34GF 15
CAS:<p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>Fórmula:C23H21ClO6Pureza:98%Cor e Forma:SolidPeso molecular:428.86TOK-8801
CAS:<p>TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.</p>Fórmula:C17H21N3OSPureza:99.97%Cor e Forma:SolidPeso molecular:315.43Mivobulin
CAS:<p>Mivobulin is an inhibitor of tubulin .</p>Fórmula:C17H19N5O2Pureza:98%Cor e Forma:SolidPeso molecular:325.37S-methyl DM1
CAS:<p>S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.</p>Fórmula:C36H50ClN3O10SPureza:98%Cor e Forma:SolidPeso molecular:752.31Cevipabulin
CAS:<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Fórmula:C18H18ClF5N6OPureza:99.53%Cor e Forma:SolidPeso molecular:464.82Tau-aggregation and neuroinflammation-IN-1
CAS:<p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>Fórmula:C25H20N2O7Pureza:99.85%Cor e Forma:SolidPeso molecular:460.44CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Fórmula:C14H9N3OPureza:98.38%Cor e Forma:SolidPeso molecular:235.24S516
CAS:<p>S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.</p>Fórmula:C21H19N5O4SPureza:98%Cor e Forma:SolidPeso molecular:437.47Tubulin inhibitor 8
CAS:<p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>Fórmula:C21H14N2O3Pureza:98.51% - 99.87%Cor e Forma:SolidPeso molecular:342.35LY3372689
CAS:<p>LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.</p>Fórmula:C16H22FN5O3SPureza:99.43% - 99.53%Cor e Forma:SolidPeso molecular:383.44
