Microtúbulo associado
Os inibidores de proteínas associadas aos microtúbulos têm como alvo as proteínas que interagem com os microtúbulos, os componentes estruturais do citoesqueleto da célula que são essenciais para a divisão celular. Essas proteínas regulam a estabilidade e a dinâmica dos microtúbulos durante a mitose. A inibição de proteínas associadas aos microtúbulos pode interromper a função dos microtúbulos, levando à parada do ciclo celular e à apoptose, especialmente em células cancerígenas de rápida divisão. Esses inibidores são amplamente utilizados na pesquisa do câncer e no desenvolvimento de medicamentos. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteínas associadas aos microtúbulos de alta qualidade para apoiar sua pesquisa em divisão celular, dinâmica do citoesqueleto e terapia do câncer.
Foram encontrados 283 produtos de "Microtúbulo associado"
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Combretastatin A-1 phosphate tetrasodium
CAS:OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Fórmula:C18H18Na4O12P2Cor e Forma:SolidPeso molecular:580.24Pironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Fórmula:C19H32O4Pureza:98%Cor e Forma:SolidPeso molecular:324.45Dihydrocephalomannine
CAS:Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.Fórmula:C45H55NO14Pureza:98%Cor e Forma:SolidPeso molecular:833.928Tubulin inhibitor 24
CAS:Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Fórmula:C22H21N3O3Pureza:99.99%Cor e Forma:SolidPeso molecular:375.42Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Cor e Forma:Odour SolidCeratamine A
CAS:<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Fórmula:C17H16Br2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:468.14Epothilone F
CAS:Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Fórmula:C27H41NO7SCor e Forma:SolidPeso molecular:523.68Phomopsin A
CAS:Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.Fórmula:C36H45ClN6O12Pureza:98%Cor e Forma:SolidPeso molecular:789.23Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cellFórmula:C17H13ClN6OSCor e Forma:SolidPeso molecular:384.8410-Oxo Docetaxel
CAS:10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Fórmula:C43H51NO14Pureza:98%Cor e Forma:SolidPeso molecular:805.874Diminutol
CAS:Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.Fórmula:C19H26N6OSCor e Forma:SolidPeso molecular:386.51Anticancer agent 270
Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.Cor e Forma:Odour SolidMicrotubule destabilizing agent-1
CAS:Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.Fórmula:C22H26N4O4Cor e Forma:SolidPeso molecular:410.477-Epi-docetaxel
CAS:7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.Fórmula:C43H53NO14Pureza:98%Cor e Forma:SolidPeso molecular:807.88Vinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Fórmula:C45H54F2N4O8·xC4H6O6Pureza:98%Cor e Forma:SolidPeso molecular:967.02Cys-McMMAF
CAS:Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.Fórmula:C52H83N7O13SCor e Forma:SolidPeso molecular:1046.32Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breastFórmula:C22H25NO6Cor e Forma:SolidPeso molecular:399.44ALB-109564 dihydrochloride
CAS:ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.Fórmula:C47H62Cl2N4O9SPureza:98%Cor e Forma:SolidPeso molecular:929.997-Epi-10-oxo-docetaxel
CAS:7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.Fórmula:C43H51NO14Pureza:98%Cor e Forma:SolidPeso molecular:805.86Tubulin inhibitor 21
Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.Fórmula:C28H25N3O4SCor e Forma:SolidPeso molecular:499.58
