Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2252 produtos de "Cromatina/Epigenética"
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TH1834
CAS:<p>TH1834 is a specific inhibitor of Tip60/KAT5 histone acetyltransferase. TH1834 induces apoptosis and DNA damage in MCF.</p>Fórmula:C33H40N6O3Pureza:99.96%Cor e Forma:SolidPeso molecular:568.71MC4171
<p>MC4171 is a selective KAT8 inhibitor with antiproliferative activity and can be used to study cancer.</p>Fórmula:C21H15N3O3Pureza:99.56%Cor e Forma:SolidPeso molecular:357.36N-Descyclopropanecarbaldehyde Olaparib
CAS:<p>N-Descyclopropanecarbaldehyde Olaparib is a CRBN ligand for dual EGFR/PARP PROTAC, suitable for F-18 radiolabeling and tumor imaging via PET.</p>Fórmula:C20H19FN4O2Cor e Forma:SolidPeso molecular:366.39DTP3
CAS:<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Fórmula:C26H35N7O5Cor e Forma:SolidPeso molecular:525.6KDM4C-IN-1
CAS:KDM4C-IN-1 is aKDM4C inhibitor withial anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.Fórmula:C15H14N4O3Pureza:99.33%Cor e Forma:SolidPeso molecular:298.3AZ505 ditrifluoroacetate
CAS:AZ505 ditrifluoroacetate is an effective and selective SMYD2 inhibitor (IC50: 0.12 μM).Fórmula:C33H40Cl2F6N4O8Cor e Forma:SolidPeso molecular:805.59(2R)-Octyl-α-hydroxyglutarate
CAS:(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.Fórmula:C13H24O5Cor e Forma:SolidPeso molecular:260.33SGC-iMLLT
CAS:SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular targetFórmula:C22H24N6OPureza:99.21% - 99.92%Cor e Forma:SolidPeso molecular:388.47GSK2879552
CAS:GSK2879552: oral, irreversible LSD1 inhibitor with potential cancer-fighting properties.Fórmula:C23H28N2O2Pureza:99.22%Cor e Forma:SolidPeso molecular:364.48GSK778
CAS:GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.Fórmula:C30H33N5O3Pureza:98.42%Cor e Forma:SolidPeso molecular:511.61AS-85
CAS:<p>AS-85 is an ASH1L inhibitor with anti-leukemic activity that inhibits leukemic cell growth and increases cLogP.</p>Fórmula:C26H28F3N5O3S2Pureza:98.96%Cor e Forma:SolidPeso molecular:579.66KDM4-IN-3
CAS:<p>KDM4-IN-3 is a KDM4 inhibitor that is cell-permeable and kills prostate cancer cells at low micromolar concentrations.</p>Fórmula:C17H14N4OCor e Forma:SolidPeso molecular:290.32TPOP146
CAS:TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).Fórmula:C27H35N3O5Pureza:98%Cor e Forma:SolidPeso molecular:481.58GSK-J2
CAS:GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.Fórmula:C22H23N5O2Pureza:97.55%Cor e Forma:SolidPeso molecular:389.45PROTAC EZH2 Degrader-1
CAS:PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.Fórmula:C54H67N7O8Cor e Forma:SolidPeso molecular:942.15Itacitinib adipate
CAS:Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.Fórmula:C32H33F4N9O5Cor e Forma:SolidPeso molecular:699.66Boc-Lys(Ac)-AMC
CAS:<p>Boc-Lys(Ac)-AMC (Boc-L-Lys(Ac)-AMC) is a synthetic substrate coupled to an HDAC-specific fluorophore (Ex/Em = 355 nm/460 nm).</p>Fórmula:C23H31N3O6Pureza:99.87%Cor e Forma:SolidPeso molecular:445.51CHZ868
CAS:<p>CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.</p>Fórmula:C22H19F2N5O2Pureza:99.38%Cor e Forma:SolidPeso molecular:423.42ADTL-SA1215
CAS:<p>ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.</p>Fórmula:C26H29I2NO3Pureza:99.23%Cor e Forma:SolidPeso molecular:657.32GSK9311
CAS:<p>GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively).</p>Fórmula:C24H31N5O3Pureza:98%Cor e Forma:SolidPeso molecular:437.53
