Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2235 produtos de "Cromatina/Epigenética"
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I-BET787
CAS:<p>I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.</p>Fórmula:C16H20ClN3O2Cor e Forma:SolidPeso molecular:321.80CrBKA
CAS:<p>CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .</p>Fórmula:C28H31N3O6Cor e Forma:SolidPeso molecular:505.56AdipoR agonist 1
CAS:<p>AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.</p>Fórmula:C26H35N3O3Cor e Forma:SolidPeso molecular:437.57HDAC6-IN-27
CAS:<p>HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].</p>Fórmula:C15H15N3O4Cor e Forma:SolidPeso molecular:301.3BG47
CAS:<p>BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.</p>Fórmula:C25H22N4O2SCor e Forma:SolidPeso molecular:442.54Guanosine-5'-triphosphate disodium salt
CAS:<p>5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.</p>Fórmula:C10H14N5Na2O14P3Pureza:95.69% - 99.96%Cor e Forma:Odorless White SolidPeso molecular:567.14GSK-J1 lithium salt
CAS:<p>GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.</p>Fórmula:C22H22LiN5O2Pureza:98%Cor e Forma:SolidPeso molecular:395.38BG14
CAS:<p>BG14: High-res optical epigenetic control; photo-inhibits human histone deacetylases with visible light.</p>Fórmula:C21H21N5OCor e Forma:SolidPeso molecular:359.433KAT6-IN-1
CAS:<p>KAT6-IN-1 is a potent KAT6 inhibitor. KAT6-IN-1 can be used in research of cancer [1] .</p>Fórmula:C19H18N4O5SCor e Forma:SolidPeso molecular:414.43ZM39923
CAS:<p>ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM).</p>Fórmula:C23H25NOPureza:98%Cor e Forma:SolidPeso molecular:331.45KR-39038
CAS:<p>KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.</p>Fórmula:C24H32ClFN6OCor e Forma:SolidPeso molecular:475.00BChE/HDAC6-IN-2
CAS:<p>BChE/HDAC6-IN-2 is an inhibitor of BChE and HDAC6 with neuroprotective and ROS scavenging activity and a metal ion co-agonist and inhibits tau phosphorylation.</p>Fórmula:C27H30N4O4Pureza:98.47%Cor e Forma:SoildPeso molecular:474.55BG48
CAS:<p>BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.</p>Fórmula:C25H23N5OSCor e Forma:SolidPeso molecular:441.55(3S,4S)-Tofacitinib
CAS:<p>(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.</p>Fórmula:C16H20N6OPureza:98%Cor e Forma:SolidPeso molecular:312.37Asteltoxin
CAS:<p>Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.</p>Fórmula:C23H30O7Cor e Forma:SolidPeso molecular:418.486HDAC2-IN-2
CAS:<p>HDAC2-IN-2 (compound 124) acts as an HDAC2 inhibitor, exhibiting a Kd value ranging from 0.1-1 μM.</p>Fórmula:C18H15N3O3SCor e Forma:SolidPeso molecular:353.40E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Fórmula:C21H30O6Pureza:99.52%Cor e Forma:SolidPeso molecular:378.46TMPA
CAS:<p>TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.</p>Fórmula:C21H32O6Pureza:99.21%Cor e Forma:SolidPeso molecular:380.48GSK-1268997
CAS:<p>GSK-1268997 is a bio-active chemical.</p>Fórmula:C21H23N7O3SPureza:99.33% - 99.81%Cor e Forma:SolidPeso molecular:453.52UNC0224
CAS:<p>UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.</p>Fórmula:C26H43N7O2Pureza:99.80%Cor e Forma:SolidPeso molecular:485.67
