Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2238 produtos de "Cromatina/Epigenética"
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KF 13218
CAS:<p>KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.</p>Fórmula:C20H20N2O3Pureza:98%Cor e Forma:SolidPeso molecular:336.38LP99
CAS:<p>LP99 is an epigenetic probe.</p>Fórmula:C26H30ClN3O4SPureza:99.74%Cor e Forma:SolidPeso molecular:516.05TM6089
CAS:<p>TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.</p>Fórmula:C13H14N4O3SPureza:99.70%Cor e Forma:SolidPeso molecular:306.34PRMT4-IN-1
CAS:<p>PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].</p>Fórmula:C23H28FN3OPureza:98%Cor e Forma:SolidPeso molecular:381.49HDAC1/MAO-B-IN-1
CAS:<p>HDAC1/MAO-B-IN-1 is a selective Alzheimer’s research inhibitor with IC50s: HDAC1 (21.4 nM) & MAO-B (99 nM); crosses the blood-brain barrier.</p>Fórmula:C18H17ClN2O2Cor e Forma:SolidPeso molecular:328.79BET bromodomain inhibitor 3
CAS:<p>BET Bromodomain Inhibitor 3 is a BET bromodomain inhibitor with an inhibitory Ki value of >40 µM against BrdT.</p>Fórmula:C18H17N3O4Pureza:98%Cor e Forma:SolidPeso molecular:339.35HDAC-IN-30
CAS:<p>HDAC-IN-30 is a potent HDAC inhibitor targeting HDAC1, 2, 3, 6, and 8 with strong antitumor efficacy.</p>Fórmula:C22H23N5O3Cor e Forma:SolidPeso molecular:405.45SGC6870
CAS:<p>SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.</p>Fórmula:C23H21BrN2O2SCor e Forma:SolidPeso molecular:469.39PARP11 inhibitor ITK7
CAS:<p>ITK7 is a potent, selective PARP11 inhibitor with an IC50 of 14 nM, useful for cellular localization research.</p>Fórmula:C17H14N4OSCor e Forma:SolidPeso molecular:322.38Y06036
CAS:<p>Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).</p>Fórmula:C16H15BrN2O5SPureza:99.97%Cor e Forma:SolidPeso molecular:427.27BRD4 Inhibitor-19
CAS:<p>BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.</p>Fórmula:C29H25N5O3Cor e Forma:SolidPeso molecular:491.54PRMT5-IN-2
CAS:<p>PRMT5-IN-2 is an inhibitor of protein arginine methyltransferase 5.</p>Fórmula:C17H16ClFN4O4Pureza:98%Cor e Forma:SolidPeso molecular:394.78NCD38
CAS:<p>NCD38 is a potent, selective LSD1 inhibitor.</p>Fórmula:C37H37ClF3N3O4Pureza:98.21% - 98.86%Cor e Forma:SolidPeso molecular:680.16(Rac)-BAY1238097
CAS:<p>(Rac)-BAY1238097 is a inhibitor of BET(IC50 of 1.02 μM for BRD4),used in cancer research.</p>Fórmula:C25H33N5O3Pureza:98%Cor e Forma:SolidPeso molecular:451.56HDAC-IN-41
CAS:<p>HDAC-IN-41 is a selective class I HDAC inhibiting HDAC1, 2, & 3 with IC50: 0.62-1.46 µM; oral use; has NO-release.</p>Fórmula:C20H22N4O6SCor e Forma:SolidPeso molecular:446.48EZM 2302
CAS:<p>EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).Cost-effective and quality-assured.</p>Fórmula:C29H37ClN6O5Pureza:97.47% - ≥98%Cor e Forma:SolidPeso molecular:585.09HDAC6-IN-11
CAS:<p>HDAC6-IN-11 (Compound 9) is a cancer cell growth blocker, selectively inhibiting HDAC6 (>300-fold) with an IC50 of 20.7 nM.</p>Fórmula:C19H16N2O4Cor e Forma:SolidPeso molecular:336.34Furamidine
CAS:<p>Furamidine is a PRMT1-selective, cell-permeable inhibitor (IC50: 9.4μM), also targeting TDP-1, and is an antiparasitic bisbenzamidine derivative.</p>Fórmula:C18H16N4OPureza:98%Cor e Forma:SolidPeso molecular:304.35BI-831266
CAS:<p>BI-831266 is a potent and selective Aurora kinase B inhibitor.</p>Fórmula:C27H38ClN7O2Cor e Forma:SolidPeso molecular:528.09JFD00244
CAS:<p>JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.</p>Fórmula:C30H26N2O4Pureza:98%Cor e Forma:SolidPeso molecular:478.54
