
Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2242 produtos de "Cromatina/Epigenética"
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MAT2A-IN-7
CAS:<p>MAT2A-IN-7 inhibits MAT2A in various cancers, especially MTAP-deficient cancer cells, with potential for research use.</p>Fórmula:C17H13ClF3N3O2Cor e Forma:SolidPeso molecular:383.755WKS
CAS:<p>5WKS, or ZINC97756584, is a G9a inhibitor targeting H3K9me2 for gene silencing research in autoimmune diseases and tumors.</p>Fórmula:C24H36ClN5O2Pureza:98%Cor e Forma:SolidPeso molecular:462.03JS1310
CAS:<p>JS1310 is a selective PRMT7 inhibitor (IC50: 5 μM against human PRMT7). JS1310 has shown anti-cancer effects on different cancer cells.</p>Fórmula:C23H22FN5O3Cor e Forma:SolidPeso molecular:435.45CL67
CAS:<p>CL67 is a hypoxia-inducible factor pathway inhibitor. It acts by binding to a G-quadruplex higher-order structure in the HIF promoter sequence in vitro.</p>Fórmula:C38H42N10O2Cor e Forma:SolidPeso molecular:670.81HAT-IN-1
CAS:<p>HAT-IN-1 is an inhibitor of HAT used in the research of cancer.</p>Fórmula:C23H18BrF4N3O4Pureza:98%Cor e Forma:SolidPeso molecular:556.3Galegine hydrochloride
CAS:<p>Galegine hydrochloride, from G. officinalis, leads to weight loss, activates AMPK in various cells, and has antibacterial properties.</p>Fórmula:C6H14ClN3Cor e Forma:SolidPeso molecular:163.65PDAT
CAS:<p>PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor.</p>Fórmula:C15H23N3Pureza:98%Cor e Forma:SolidPeso molecular:245.36TM6008
CAS:<p>TM6008 is an inhibitor of prolyl hydroxylase that protects against cell death after hypoxia.</p>Fórmula:C21H17N5O3Pureza:98%Cor e Forma:SolidPeso molecular:387.39CPI703
CAS:<p>CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.</p>Fórmula:C17H22N4OPureza:98%Cor e Forma:SolidPeso molecular:298.38SKF 91488 dihydrochloride
CAS:<p>histamine N-methyltransferase inhibitor</p>Fórmula:C7H19Cl2N3SPureza:98%Cor e Forma:SolidPeso molecular:248.22SRI-42127
CAS:<p>SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR that inhibits tumor growth and reduces neuropathic pain following nerve injury.</p>Fórmula:C19H20N6OPureza:99.66%Cor e Forma:SolidPeso molecular:348.41,2-Didecanoylglycerol
CAS:<p>1,2-Didecanoylglycerol has functions as bioregulator of protein kinase C in human platelets.</p>Fórmula:C23H44O5Cor e Forma:SolidPeso molecular:400.59CTX-0124143
CAS:<p>CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.</p>Fórmula:C17H13FN2O3SPureza:99.16%Cor e Forma:SolidPeso molecular:344.36EZH2-IN-7
CAS:<p>EZH2-IN-7 inhibits EZH2, reducing H3K27me3 and tumor growth (e.g., breast, prostate cancer, leukemia). Potential in cancer research.</p>Fórmula:C31H37D2N5O3SCor e Forma:SolidPeso molecular:563.75IHCH-3064
CAS:<p>IHCH-3064: dual-action cancer immunotherapy, A2AR affinity (Ki 2.2 nM), selective HDAC1 inhibitor (IC50 80.2 nM).</p>Fórmula:C25H21N9O2Cor e Forma:SolidPeso molecular:479.49TUL01101
CAS:<p>TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.</p>Fórmula:C22H25F2N5O2Cor e Forma:SolidPeso molecular:429.46JAK3i
CAS:<p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>Fórmula:C18H15FN4O3Pureza:98.61% - 99.81%Cor e Forma:SolidPeso molecular:354.345-Aza-4'-thio-2'-deoxycytidine
CAS:<p>5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].</p>Fórmula:C8H12N4O3SCor e Forma:SolidPeso molecular:244.27EML741
CAS:<p>EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b.</p>Fórmula:C31H49N5O2Pureza:98%Cor e Forma:SolidPeso molecular:523.75TyK2-IN-2
CAS:<p>TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).</p>Fórmula:C16H18N6OPureza:98%Cor e Forma:SolidPeso molecular:310.35
