Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2490 produtos de "Cromatina/Epigenética"
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Dimethyl-bisphenol A
CAS:DMBPA inhibits HIF-1α, promotes its degradation by detaching Hsp90, and reduces Vegfa mRNA expression.Fórmula:C17H20O2Cor e Forma:SolidPeso molecular:256.34CMP-5 hydrochloride
CAS:CMP-5 hydrochloride: potent, selective PRMT5 inhibitor; inactive against PRMT1/4/7; blocks S2Me-H4R3 on histones.Fórmula:C21H22ClN3Pureza:98%Cor e Forma:SolidPeso molecular:351.87BAY1238097
CAS:BAY1238097 is a BET inhibitor with anticancer activity and antiproliferative activity for the study of advanced refractory malignancies.Fórmula:C25H33N5O3Pureza:98.1% - 98.79%Cor e Forma:SolidPeso molecular:451.56Ref: TM-T12660L
1mg49,00€5mg101,00€10mg172,00€25mg355,00€50mg620,00€100mg1.044,00€200mg1.404,00€1mL*10mM (DMSO)113,00€UNC2327
CAS:UNC2327 is a potent and selective inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50:230 nM).Fórmula:C14H17N5O2SPureza:98%Cor e Forma:SolidPeso molecular:319.38CPI703
CAS:CPI703 is a novel potent and specific CBP/EP300 bromodomain inhibitor.Fórmula:C17H22N4OPureza:98%Cor e Forma:SolidPeso molecular:298.38TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Fórmula:C16H18N6OPureza:98%Cor e Forma:SolidPeso molecular:310.35TK4g
CAS:TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) & 15.80 nM (JAK3); promising for lymphoid diseases & leukemia research.Fórmula:C19H19N3O4SCor e Forma:SolidPeso molecular:385.44BRD4 Inhibitor-19
CAS:BRD4 inhibitors -19 are BET inhibitors that act on BRD4-BD1 (IC50: 55 nM) and can be used to study multiple myeloma.Fórmula:C29H25N5O3Cor e Forma:SolidPeso molecular:491.54PI3K/HDAC-IN-1
CAS:PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).
Fórmula:C22H25FN4O4Pureza:98%Cor e Forma:SolidPeso molecular:428.466-Methyl-5-azacytidine
CAS:6-Methyl-5-azacytidine is a potent DNMT inhibitor.Fórmula:C9H14N4O5Pureza:98%Cor e Forma:SolidPeso molecular:258.23Dot1L-IN-7
CAS:Dot1L-IN-7 (compound 25), a potent DOT1L inhibitor with an IC50 of 1.0 μM, selectively kills MLL-AF9, sparing E2A-HLF cells.Fórmula:C23H27N9O2Cor e Forma:SolidPeso molecular:461.52Piribedil dihydrochloride
CAS:dopamine agonistFórmula:C16H20Cl2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:371.26MI-1
CAS:MI-1 inhibits Menin-MLL interaction with an IC 50 of 1.9 μM [1].Fórmula:C19H25N5S2Cor e Forma:SolidPeso molecular:387.57KBH-A42
CAS:KBH-A42 is an inhibitor of histone deacetylase.Fórmula:C17H22N2O3Pureza:98%Cor e Forma:SolidPeso molecular:302.37DS-437
CAS:DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.Fórmula:C15H23N7O4SPureza:98%Cor e Forma:SolidPeso molecular:397.45Tankyrase-IN-4
Tankyrase-IN-4 is a potent inhibitor of tankyrase 1 (TNKS1), exhibiting an IC50 of 0.8 nM, and is utilized in cancer research.Fórmula:C25H24N6O5Cor e Forma:SolidPeso molecular:488.5DCE_42
CAS:DCE_42 is a novel EZH2 inhibitor, it also displays significant anti-proliferation activity against lymphoma cell lines.Fórmula:C22H19N9O2SPureza:98%Cor e Forma:SolidPeso molecular:473.51SGC6870
CAS:SGC6870 is a novel potent, selective, and cell-active inhibitor of PRMT6 with IC50 of 77 ± 6 nM, being selective over all other PRMTs and 23 methyltransferases.Fórmula:C23H21BrN2O2SCor e Forma:SolidPeso molecular:469.39PIM1-IN-6
CAS:PIM1-IN-6 (5h) inhibits PIM-1 (IC50: 0.60 μM) and is cytotoxic to HCT-116 (IC50: 1.51 μM) and MCF-7 cells (IC50: 15.2 μM).Fórmula:C21H18N6O4Cor e Forma:SolidPeso molecular:418.41DPQ
CAS:DPQ inhibits PARP-1, aids in neuroprotection, restores ATP, and lessens neuronal injury from NMDA.
Fórmula:C18H26N2O2Pureza:98%Cor e Forma:SolidPeso molecular:302.41
