DNA Metiltransferase
As metiltransferases de DNA (DNMTs) são enzimas que catalisam a adição de grupos metila a resíduos de citosina no DNA, levando ao silenciamento gênico. A metilação aberrante do DNA está associada a várias doenças, incluindo câncer. Inibidores de DNMT bloqueiam a atividade dessas enzimas, levando à reativação de genes silenciados e à indução de apoptose em células cancerígenas. Os inibidores de DNMT são amplamente utilizados em pesquisas epigenéticas e terapias contra o câncer. Na CymitQuimica, oferecemos uma gama de inibidores de DNMT de alta qualidade para apoiar sua pesquisa em epigenética, metilação de DNA e biologia do câncer.
Foram encontrados 472 produtos para "DNA Metiltransferase".
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rel-A-395 hydrochloride
CAS:rel-A-395 hydrochloride is the relative configuration of A-395 hydrochloride. A-395 is an antagonist of protein-protein interactions within the polycomb repressive complex 2 (PRC2). It inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 value of 18 nM.Fórmula:C26H36ClFN4O2SCor e Forma:SolidPeso molecular:523.11SARS-CoV-2 nsp14-IN-1
SARS-CoV-2 nsp14-IN-1 inhibits Nsp14 Mtase with an IC50 of 0.061 μM, affecting multiple substrates.Fórmula:C20H20N6O5SCor e Forma:SolidPeso molecular:456.48MRK-740-NC
CAS:MRK-740-NC is an inhibitor of the PRDM7/9 histone methyltransferase. Acting as the negative control compound for MRK-740, MRK-740-NC lacks inhibitory activity on PRDM7 and PRDM9 because the methylpyridine portion of MRK-740 is replaced with a phenyl group.Fórmula:C25H31N5O3Cor e Forma:SolidPeso molecular:449.55NSD2-IN-5
CAS:NSD2-IN-5 (Compound 198) is an NSD2 inhibitor with an IC50 value ranging from 0.001 μM to 0.01 μM. It is utilized for cancer research.Fórmula:C27H25F2N9Peso molecular:513.56HbF inducer-1
HbF inducer-1 is a fetal hemoglobin inducer which is orally bioavailable.Fórmula:C18H19N3O3Cor e Forma:SolidPeso molecular:325.36GSK3368715 dihydrochloride
CAS:GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is a PRMTs inhibitor , with anticancer activity, for the study of advanced solid tumors.Fórmula:C20H40Cl2N4O2Pureza:99.66% - 99.66%Cor e Forma:White SolidPeso molecular:439.46ORIC-944
CAS:ORIC-944 is an orally available, selective variant of PRC2 with anticancer activity for the study of prostate cancer.Fórmula:C26H25FN6OPureza:98.08%Cor e Forma:Yellow SolidPeso molecular:456.52Ref: TM-T87073
1mg70,00€5mg137,00€1mL*10mM (DMSO)147,00€10mg197,00€25mg334,00€50mg434,00€100mg655,00€EZM0414
CAS:EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 with IC50 of 18 nM in SETD2 biochemical assay and IC50 of 34 nM in a cellular assay.Fórmula:C22H29FN4O2Pureza:99.58%Cor e Forma:SolidPeso molecular:400.49AMG-193
CAS:AMG-193 is an inhibitor of the MTA-PRMT5 complex and is used in the study of cancer, respiratory diseases and digestive disorders.Fórmula:C22H19F3N4O3Pureza:99.92%Cor e Forma:SolidPeso molecular:444.41Ref: TM-T85645
10mgA consultar25mgA consultar50mgA consultar100mgA consultar1mg50,00€5mg99,00€1mL*10mM (DMSO)109,00€BRD0639
CAS:BRD0639 is a first-in-class PRMT5-substrate interaction inhibitor for PBM-dependent PRMT5 activity studies.Fórmula:C21H22ClN5O4SPureza:99.85%Cor e Forma:SolidPeso molecular:475.95Sinefungin
CAS:Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viralFórmula:C15H23N7O5Pureza:98% - 98.12%Cor e Forma:White SolidPeso molecular:381.39PROTAC EZH2 Degrader-1
CAS:PROTAC EZH2 Degrader-1 suppresses EZH2 methyltransferase activity with IC50 2.7 nM, serving as a potent tool in cancer research and EZH2 inhibition studies.Fórmula:C54H67N7O8Cor e Forma:White SolidPeso molecular:942.15Ref: TM-T74602
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