Enzima
Os inibidores de enzimas são moléculas que se ligam a enzimas e diminuem sua atividade. Esses inibidores são amplamente utilizados em pesquisas para estudar a cinética enzimática, regulação e o papel de enzimas específicas nas vias metabólicas. Os inibidores de enzimas também são cruciais no desenvolvimento de medicamentos, pois muitos agentes terapêuticos funcionam inibindo enzimas envolvidas em processos patológicos. Ao direcionar enzimas, esses inibidores podem modular vias bioquímicas e oferecer tratamentos potenciais para várias doenças. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de enzimas de alta qualidade para apoiar sua pesquisa em bioquímica, farmacologia e descoberta de medicamentos.
Subcategorias de "Enzima"
- Anidrase carbónica(177 produtos)
- Hidroxilase(30 produtos)
- MPO(2 produtos)
- Redutase(52 produtos)
- Tirosinase(67 produtos)
Foram encontrados 3586 produtos de "Enzima"
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Carbonic anhydrase inhibitor 30
<p>Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].</p>Fórmula:C23H22FN3O5SCor e Forma:SolidPeso molecular:471.12642hCAXII-IN-7
<p>hCAXII-IN-7 (compound 6e) functions as an inhibitor of human carbonic anhydrase XII (hCA XII) and possesses blood-brain barrier (BBB) permeability.</p>Fórmula:C26H25N5O6S2Pureza:98%Cor e Forma:SolidPeso molecular:567.64hCA/VEGFR-2-IN-2
<p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>Fórmula:C23H26N6O5SPureza:98%Cor e Forma:SolidPeso molecular:498.55hCA/VEGFR-2-IN-4
<p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>Fórmula:C22H23FN6O5SPureza:98%Cor e Forma:SolidPeso molecular:502.52hCAIX/XII-IN-14
<p>hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.</p>Fórmula:C16H14F3N3O4SCor e Forma:SolidPeso molecular:401.36α-Pyrone
CAS:<p>Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9</p>Fórmula:C5H4O2Cor e Forma:SolidPeso molecular:96.08Carbonic anhydrase
CAS:<p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>Cor e Forma:SolidCAIX/CAXII-IN-4
<p>CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.</p>Fórmula:C23H21N5O3SCor e Forma:SolidPeso molecular:447.51TSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Fórmula:C35H51N3O3Cor e Forma:SolidPeso molecular:561.798Tyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Cor e Forma:Odour SolidGirentuximab
CAS:<p>Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).</p>Cor e Forma:LiquidPeso molecular:145.55 kDaTyrosinase-IN-40
<p>Tyrosinase-IN-40 (Compound 9r) is a competitive inhibitor of tyrosinase, boasting an IC50 value of 17.02 µM and a Ki value of 14.87 µM. This compound also exhibits antioxidant activity and can be utilized in studies related to melanin.</p>Fórmula:C34H29N9O10Cor e Forma:SolidPeso molecular:723.648CAIX Inhibitor S4
CAS:<p>CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.</p>Fórmula:C15H17N3O4SPureza:99.07%Cor e Forma:SolidPeso molecular:335.38hCAII-IN-8
CAS:<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Fórmula:C15H16N2O5SPureza:99.73%Cor e Forma:SoildPeso molecular:336.36Carbonic anhydrase inhibitor 32
<p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>Fórmula:C17H16N6O3SCor e Forma:SolidPeso molecular:384.41Carbonic anhydrase inhibitor 31
<p>Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.</p>Fórmula:C24H20N6O5SCor e Forma:SolidPeso molecular:504.12159hCAIX-IN-17
<p>hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.</p>Fórmula:C19H18N2O3SCor e Forma:SolidPeso molecular:354.42hCAII/XII-IN-1
<p>hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.</p>Fórmula:C22H20N4O6S2Cor e Forma:SolidPeso molecular:500.547CA IX/VEGFR-2-IN-3
<p>CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.</p>Fórmula:C19H16ClN3O5S2Cor e Forma:SolidPeso molecular:465.93hCA/VEGFR-2-IN-3
<p>hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.</p>Fórmula:C24H28N6O6SPureza:98%Cor e Forma:SolidPeso molecular:528.58Peroxidase
CAS:Pureza:≥ 85units/mg (dry basis)Cor e Forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecular:-hCAII/IX-IN-1
<p>hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.</p>Fórmula:C23H22N4O7S2Cor e Forma:SolidPeso molecular:530.573hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Cor e Forma:Odour SolidCarbonic anhydrase inhibitor 29
<p>Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.</p>Cor e Forma:Odour SolidPyridine-2-aldoxime methochloride
CAS:Fórmula:C7H9N2O·ClPureza:≥ 98.0%Cor e Forma:White to off-white or light yellow crystalline powderPeso molecular:172.61CAXII-IN-2
<p>CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.</p>Fórmula:C16H13FNO4PCor e Forma:SolidPeso molecular:333.05662IOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Cor e Forma:SoildPeso molecular:367.36α-Glycosidase-IN-2
<p>α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.</p>Fórmula:C25H22N6OS2Cor e Forma:SolidPeso molecular:486.61DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Fórmula:C17H20N2O5SCor e Forma:SolidPeso molecular:364.42Trypsin, bovine origin
CAS:Pureza:≥ 2000units/mg (USP)Cor e Forma:White or almost white crystalline powderPeso molecular:-Phenylsulfamide
CAS:<p>Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an</p>Fórmula:C6H8N2O2SCor e Forma:SolidPeso molecular:172.2hCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Fórmula:C13H10FN3O4Peso molecular:291.06553TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Cor e Forma:Odour SolidAc-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:<p>Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect</p>Fórmula:C47H64N14O10Cor e Forma:SolidPeso molecular:985.1Tyrosinase-IN-14
<p>Tyrosinase-IN-14 (compound 7m), a tyrosinase inhibitor, modulates the enzyme's secondary structure to diminish its catalytic function, exhibits low cytotoxicity</p>Fórmula:C21H13Br2N3O3SPureza:98%Cor e Forma:SolidPeso molecular:547.22Peroxidase, from horseradish, approx. 200 U/mg
CAS:Pureza:≥ 150U/mgCor e Forma:Beige to light-brown, reddish brown or dark brown lyophilised powderPeso molecular:-Proteinase K
CAS:Pureza:≥ 30units/mg (pH 7.5, 37°C, dried basis)Cor e Forma:White or almost white lyophilized powderPeso molecular:-Tyrosinase-IN-34
<p>Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.</p>Fórmula:C19H14BrClN4OCor e Forma:SolidPeso molecular:429.7Tyrosinase-IN-32
<p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>Fórmula:C15H19NO3Cor e Forma:SolidPeso molecular:261.32Lysozyme, from chicken egg white
CAS:Pureza:≥ 20,000U/mgCor e Forma:White to off-white powderPeso molecular:-TrkA Protein, Rabbit, Recombinant (His)
<p>TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:43.4 kDa (predicted)TrkB Protein, Canine, Recombinant (hFc)
<p>TrkB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:71.2 kDa (predicted)TrkA Protein, Rat, Recombinant (hFc)
<p>TrkA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:69.2 kDa (predicted); 92-102 kDa (reducing conditions)Cuprizone
CAS:<p>Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.</p>Fórmula:C14H22N4O2Pureza:≥98%Cor e Forma:SolidPeso molecular:278.35TrkA Protein, Human, Recombinant (His)
<p>TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:98.7%Cor e Forma:Lyophilized PowderPeso molecular:39.5 kDa (predicted); 60-65 kDa (reducing condition, due to glycosylation)HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
<p>Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes,</p>Cor e Forma:Lyophilized PowderPeso molecular:69.54 kDa (predicted). Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result.p38 γ/MAPK12 Protein, Human, Recombinant
<p>p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells.</p>Cor e Forma:Lyophilized PowderPeso molecular:42.1 kDa (predicted); 43 kDa (reducing conditions)Thrombopoietin Protein, Mouse, Recombinant (C-His)
<p>Expression System: HEK293 Cells<br>Length: 22-356, Full Length of Mature Protein<br>Activity: Cell Activity</p>Peso molecular:37.20 kDa (Predicted); 75-95 kDa (Due to glycosylation)Carbonic Anhydrase 12 Protein, Human, Recombinant (His) V2
<p>Expression System: HEK293 Cells<br>Length: 25-301, Extracellular Domain<br>Activity: Enzyme Activity</p>Peso molecular:32.22 kDa (Predicted); 40-50 kDa (Due to glycosylation)ErbB4 Protein, Rat, Recombinant (His)
<p>ErbB4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:71.3 kDa (predicted); 75-95 kDa (reducing condition, due to glycosylation)TrkB Protein, Human, Recombinant (His), Biotinylated
<p>Expression system: HEK293 Cells<br>Length: 1-430, Partial<br>Activity: ELISA</p>Cor e Forma:Lyophilized PowderPeso molecular:45.66 kDa (predicted); 65.4 kDa (reducing contition, due to glycosylation)DDR2 Protein, Human, Recombinant (His & Avi), Biotinylated
<p>Expression system: HEK293 Cells<br>Length: 1-399, Partial<br>Activity: BLI</p>Cor e Forma:Lyophilized PowderPeso molecular:45.84 kDa (predicted); 60.4 kDa (reducing contition)Anti-Tyrosinase/TYR Antibody (7Z445)
<p>Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA, IF.</p>Cor e Forma:Odour LiquidTrkA Protein, Human, Recombinant
<p>TrkA Protein, Human, Recombinant is expressed in HEK293 Cells. The accession number is P04629.</p>Pureza:> 95% as analyzed by SDS-PAGE - > 95% as analyzed by SDS-PAGECor e Forma:Lyophilized PowderPeso molecular:65~85 kDa (Reducing conditions)HER3/ERBB3 Protein, Mouse, Recombinant (His)
<p>HER3/ERBB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:97.1%Cor e Forma:Lyophilized PowderPeso molecular:70 kDa (predicted); 95 kDa (reducing condition, due to glycosylation)TrkA Protein, Cynomolgus, Recombinant (His)
<p>TrkA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:43.95 kDa (predicted); 86 kDa (reducing conditions)HER3/ERBB3 Protein, Mouse, Recombinant (hFc)
<p>HER3/ERBB3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:95.23 kDa (predicted); 117.08 kDa (reducing conditions)p38 γ/MAPK12 Protein, Human, Recombinant (His & GST)
<p>p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:69.8 kDa (predicted); 65 kDa (reducing conditions)TrkB Protein, Human, Recombinant (His) V2
<p>Expression System: HEK293 Cells<br>Length: 32-430, Extracellular Domain<br>Activity: ELISA</p>Peso molecular:45.2 kDa (Predicted); 65-80 kDa (Due to glycosylation)HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
<p>Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes,</p>Cor e Forma:Lyophilized PowderPeso molecular:71.6 kDa (predicted). Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result.PTP α/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)
<p>PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways.</p>Cor e Forma:Lyophilized PowderPeso molecular:99 kDa (predicted); 90 kDa (reducing conditions)Mer Protein, Mouse, Recombinant (hFc)
<p>Mer Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:79.3 kDa (predicted); 130 kDa (reducing condition, due to glycosylation)HER3/ERBB3 Protein, Rhesus, Recombinant
<p>HER3/ERBB3 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells.</p>Pureza:92.6%Cor e Forma:Lyophilized PowderPeso molecular:69.5 kDa (predicted)HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated
<p>HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:95.4 kDa (predicted)
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