Enzima
Os inibidores de enzimas são moléculas que se ligam a enzimas e diminuem sua atividade. Esses inibidores são amplamente utilizados em pesquisas para estudar a cinética enzimática, regulação e o papel de enzimas específicas nas vias metabólicas. Os inibidores de enzimas também são cruciais no desenvolvimento de medicamentos, pois muitos agentes terapêuticos funcionam inibindo enzimas envolvidas em processos patológicos. Ao direcionar enzimas, esses inibidores podem modular vias bioquímicas e oferecer tratamentos potenciais para várias doenças. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de enzimas de alta qualidade para apoiar sua pesquisa em bioquímica, farmacologia e descoberta de medicamentos.
Subcategorias de "Enzima"
- Anidrase carbónica(197 produtos)
- Hidroxilase(36 produtos)
- MPO(2 produtos)
- Redutase(51 produtos)
- Tirosinase(71 produtos)
Foram encontrados 3621 produtos de "Enzima"
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GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Fórmula:C17H16ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:361.78hCAVII/IX-IN-1
CAS:hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.Fórmula:C7H7N3O2S2Cor e Forma:SolidPeso molecular:229.279CAII-IN-1
CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.Fórmula:C19H21FN4SCor e Forma:SolidPeso molecular:356.46β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Fórmula:C31H23NO8Cor e Forma:SolidPeso molecular:537.52Carbonic anhydrase inhibitor 2
CAS:Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.Fórmula:C12H16N4O6SCor e Forma:SolidPeso molecular:344.34CAII-IN-3
CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.Fórmula:C18H18F2N4SCor e Forma:SolidPeso molecular:360.42hCAII-IN-4
CAS:hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.Fórmula:C31H23NO9Cor e Forma:SolidPeso molecular:553.52hCAII-IN-3
hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.Fórmula:C17H21N3O3SCor e Forma:SolidPeso molecular:347.43hCAIX/XII-IN-15
CAS:hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.Fórmula:C17H18O4SCor e Forma:SolidPeso molecular:318.387Tyrosinase-IN-37
CAS:Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.Fórmula:C12H12N6SCor e Forma:SolidPeso molecular:272.33Carbonic anhydrase inhibitor 19
CAS:Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.Fórmula:C23H25N3O6S2Peso molecular:503.59Carbonic anhydrase inhibitor 17
CAS:Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.Fórmula:C18H15ClN4O3S2Peso molecular:434.92hCAIX-IN-20
CAS:hCAIX-IN-20 (compound APBS-5m) is a potent inhibitor of carbonic anhydrase IX (hCA IX), with a Ki of 2.7 nM, playing a significant role in cancer research.Fórmula:C19H13Cl2N5O4S2Peso molecular:510.37Tyrosinase-IN-33
CAS:Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.Fórmula:C19H17NS2Cor e Forma:SolidPeso molecular:323.48Tyrosinase-IN-35
CAS:Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.Fórmula:C17H15N5OSCor e Forma:SolidPeso molecular:337.40Perfluorohexane sulfonamide
CAS:Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.Fórmula:C6H2F13NO2SCor e Forma:SolidPeso molecular:399.13Isobutylamido thiazolyl resorcinol
CAS:Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.Fórmula:C13H14N2O3SCor e Forma:SolidPeso molecular:278.33Valerate sodium
CAS:Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.Fórmula:C5H9NaO2Pureza:99.84% - 99.91%Cor e Forma:SolidPeso molecular:124.11EGFR/VEGFR2-IN-2
EGFR/VEGFR2-IN-2 (compound 4b) serves as a dual inhibitor of VEGFR-2 and EGFR.Fórmula:C24H15FO3Cor e Forma:SolidPeso molecular:370.37Alkaline phosphatase
CAS:One unit of alkaline phosphatase (EC 3.1.3.1) will hydrolyze 1.0 µmol of 4-nitrophenyl phosphate per min at 25°C and pH 9.6.Pureza:Min. 95%Cor e Forma:Powder
