Enzima
Os inibidores de enzimas são moléculas que se ligam a enzimas e diminuem sua atividade. Esses inibidores são amplamente utilizados em pesquisas para estudar a cinética enzimática, regulação e o papel de enzimas específicas nas vias metabólicas. Os inibidores de enzimas também são cruciais no desenvolvimento de medicamentos, pois muitos agentes terapêuticos funcionam inibindo enzimas envolvidas em processos patológicos. Ao direcionar enzimas, esses inibidores podem modular vias bioquímicas e oferecer tratamentos potenciais para várias doenças. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de enzimas de alta qualidade para apoiar sua pesquisa em bioquímica, farmacologia e descoberta de medicamentos.
Subcategorias de "Enzima"
- Anidrase carbónica(196 produtos)
- Hidroxilase(36 produtos)
- MPO(2 produtos)
- Redutase(51 produtos)
- Tirosinase(71 produtos)
Foram encontrados 3620 produtos de "Enzima"
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EUCODIS® Nitrilhydratase 23, recombinant enzyme - ENH023
Nitrile hydratase 23 recombinantly expressed in E. coli comes in a freeze-dried formulation. Nitrile hydratases can be utilized to convert nitriles into their corresponding amides, e.g. to produce acrylamide from acrylonitrile. Additional applications include the removal of nitriles from industrial wastewater. Our nitrile hydratases have been tested for hydrolysis of the following substrates:cyclohexanecarbonitrile, cinnamonitrile, benzonitrile, methacrylonitrile, pivalonitrile.
Protein phosphatase 2C
CAS:Protein phosphatase 2C is a key enzyme, which is a serine/threonine-specific phosphatase, derived from various organisms including humans, plants, and bacteria. This enzyme plays a pivotal role in cellular signaling by removing phosphate groups from serine and threonine residues on target proteins, a process known as dephosphorylation. This action is crucial for the regulation of diverse cellular functions, including stress responses, cell division, and apoptosis.Ubiquitin Conjugating enzyme E2C Human Recombinant
Ubiquitin Conjugating enzyme E2C (other names UBE2C, UBCH10, dJ447F3.2, ubiquitin conjugating enzyme E2 C; EC 2.3.2.24) is an essential mediator of mitotic destruction events and cell cycle progression. It catalyzes the destruction of cyclins A and B in conjunction with the anaphase-promoting complex, and therefore, plays an important role in the control of the cell exit from mitosis This activity is essential at then end of mitosis for the inactivation of their partner kinase Cdc2 and exit from mitosis into G1 of the next cell cycle. In addition, UBE2C bears homology to yeast PAS2, a gene that is essential for biogenesis of peroxisomes. UBE2C is useful for in vitro ubiquitinylation reactions.Oxalate Oxidase, freeze-dried, from Wheat
CAS:Oxalate Oxidase, freeze-dried, from Wheat is an enzyme preparation which is derived from wheat and functions through the oxidative degradation of oxalate. This enzyme catalyzes the conversion of oxalate into carbon dioxide and hydrogen peroxide, utilizing oxygen as a co-substrate in the process. The activity of Oxalate Oxidase is crucial in biological and biochemical applications where oxalate degradation is required.Ref: 3D-ETS012.6
10U711,00€1KU4.680,00€25U551,00€2KU8.189,00€50U914,00€100U1.044,00€0.1KU1.020,00€0.5KU2.925,00€1000U5.429,00€2000U9.481,00€0.25KU1.802,00€Diaphorase (from Clostridium kluyveri)
CAS:Diaphorase (lipoyl dehydrogenase, EC 1.8.1.4) is an NAD+/NADH-dependent oxidoreductase. One unit of diaphorase will convert 1.0 μmole NADH into NAD+ the presence of substrate at pH 7.5 and 25 °C.Pureza:Min. 95%Urate oxidase (from Yeast)
CAS:Urate Oxidase, also known as uricase, catalizes the following reaction: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2.Fórmula:C18H26N5O14PPureza:Min. 95%Peso molecular:567.4 g/molChitinase
CAS:Chitinase (systematic name (1→4)-2-acetamido-2-deoxy-β-D-glucan glycanohydrolase, EC 3.2.1.14) is a hydrolase that breaks down glycosidic bonds in chitin. One unit of chitinase will yield 1.0 mg of N-acetyl-D-glucosamine from chitin per hour at pH 6.0 and 25 °C.Fórmula:C17H16N8ZnPureza:Min. 95%Peso molecular:397.74 g/molCitrate lyase from klebsiella pneumonia ≥0.20 unit/mg solid
CAS:Citrate lyase (also known as ATP citrate synthase, EC 2.3.3.8) is an enzyme that catalyzes the following reaction:citrate + ATP + CoA → oxaloacetate + Acetyl-CoA + ADP + PiEnzymatic activity: One unit will convert 1.0 micromole of citrate to oxalacetate per minute at pH 7.6 and 25 °C in the presence of required cofactors. Citrate lyase is supplied lyophylized, with activity ≥0.20 unit/mg solid.Pureza:Min. 95%Acid phosphatase
CAS:One unit will hydrolyse 1.0μmol of 4-nitrophenyl phosphate per minute at 37°C and pH 4.8. Substrate for enzyme analysis is the 4-nitrophenyl phosphate disodium hexahydrate (EN08508).Fórmula:C6H10O2Pureza:Min. 95%Peso molecular:114.14 g/molAmidase, from Rhodococcus sp., recombinant, lyophilized - EAM02
CAS:Amidase (EC 3.5.1.4) is a hydrolase acting on carbon-nitrogen bonds in linear amides and can be used in the hydrolysis of amides to acids. Amidase 02 is of bacterial origin (R. erythropolis and has been produced in E.coli).Lipoxidase
CAS:Lipoxidase is an enzyme, which is typically sourced from various plant tissues, animals, and some microorganisms. It functions by catalyzing the oxidation of polyunsaturated fatty acids in the presence of oxygen. This enzymatic action results in the formation of lipid hydroperoxides, which are key intermediates in various biochemical pathways, including those involved in cell signaling and the modulation of gene expression.Pureza:Min. 95%Chloroperoxidase, aqueous suspension
CAS:Chloroperoxidase (also known as chloride peroxidase, systemic name chloride:hydrogen-peroxide oxidoreductase, EC 1.11.1.10) is an enzyme that catalyzes chlorination of organic compounds. Overall reaction is the following:R-H + Cl− + H2O2 + H+ → R-Cl + 2 H2O; reaction intermediate is hypochlorous acid (HOCl). One unit of chloroperoxidase will convert 1.0 μmole of substrate per minute.
Cor e Forma:PowderC. rugosa Lipase 02, CRL 2 from Candida rugosa - ELCR02
Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The Lipase 02 from the yeast Candida rugosa has a temperature optimum in the 30 - 50 °C range and pH optimum between pH 7 and 8.Ribonuclease A
CAS:Ribonuclease A (RNase A) is widely used to break down RNA in DNA purification. RNase A catalyzes the endonucleolytic cleavage of phosphodiester bonds of RNA.C. rugosa Lipase 03, CRL 3 from Candida rugosa - ELCR03
Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The Lipase 03 from the yeast Candida rugosa has a temperature optimum in the 30 - 50 °C range and pH optimum between pH 7 and 8.C. rugosa Lipase 01, CRL 1 from Candida rugosa - ELCR01
Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. The Lipase 01 from the yeast Candida rugosa has a temperature optimum in the 30 - 50 °C range and pH optimum between pH 7 and 8.hCAIX-IN-3
CAS:hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.Fórmula:C21H21BrN6O4SCor e Forma:SolidPeso molecular:533.4L 645151
CAS:L 645151 is an inhibitor of lipophilic CA.Fórmula:C12H14N2O4S2Cor e Forma:SolidPeso molecular:314.38Tyrosinase-IN-7
CAS:Tyrosinase-IN-7 is a small-molecule tyrosinase inhibitor (IC50 1.57 μM) that suppresses melanin activity and cell growth with low cytotoxicity.Fórmula:C15H10O5Pureza:99%Cor e Forma:SolidPeso molecular:270.24hCAI/II-IN-2
CAS:hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.Fórmula:C12H12N4O5S2Cor e Forma:SolidPeso molecular:356.38Methazolamide-d6
CAS:Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.Fórmula:C5H2D6N4O3S2Cor e Forma:SolidPeso molecular:242.31HCAIX-IN-2
CAS:HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).Fórmula:C19H16N8O4SCor e Forma:SolidPeso molecular:452.45AHR-15010
CAS:AHR-15010 is a novel anti-arthritic agent.Fórmula:C10H16N2O8S2Pureza:98%Cor e Forma:SolidPeso molecular:356.37hCAI/II-IN-4
CAS:hCAI/II-IN-4 inhibits hCA I & II (Ki: 16.95 & 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.Fórmula:C15H15N3O5S2Cor e Forma:SolidPeso molecular:381.43hCAIX/XII-IN-3
CAS:Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.Fórmula:C20H13F3N2O4Cor e Forma:SolidPeso molecular:402.32FC11409B
CAS:FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.Fórmula:C29H23BF4N2O3SCor e Forma:SolidPeso molecular:566.38hCA I-IN-2
CAS:hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).Fórmula:C26H20BrN5O3SCor e Forma:SolidPeso molecular:562.44hCAXII-IN-3
CAS:hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).Fórmula:C26H20BrN5O3SCor e Forma:SolidPeso molecular:562.44CDK2-IN-11
CAS:CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.Fórmula:C18H14ClN7O2SCor e Forma:SolidPeso molecular:427.87(R)-Nepicastat HCl
CAS:(R)-Nepicastat HCl (RS-25560-198 HCl), R-enantiomer, inhibits bovine/human dopamine-β-hydroxylase (IC50: 25.1/18.3 nM); not affecting other enzymes/receptors.Fórmula:C14H15F2N3S·HClPureza:98%Cor e Forma:SolidPeso molecular:331.81Phenylthiazolylthiourea
CAS:Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor.Fórmula:C10H9N3S2Cor e Forma:SolidPeso molecular:235.33hCAIX/XII-IN-2
CAS:Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).Fórmula:C19H14N2O4Cor e Forma:SolidPeso molecular:334.33CDK2-IN-12
CAS:CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.Fórmula:C20H17N9O2SCor e Forma:SolidPeso molecular:447.47hCA I-IN-1
CAS:hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).Fórmula:C27H23N5O4SCor e Forma:SolidPeso molecular:513.57PPIE Protein, Human, Recombinant (His)
Peptidyl-prolyl cis-trans isomerase E, also known as Cyclophilin E, Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which belongs to the cyclophilin-typeCor e Forma:Lyophilized PowderPeso molecular:34 KDa (reducing condition)Ref: TM-TMPJ-01389
1mg2.535,00€5µg113,00€10µg178,00€20µg284,00€50µg523,00€100µg759,00€200µg1.103,00€500µg1.765,00€WES-1
CAS:WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,Fórmula:C20H20N4O3SPureza:98%Cor e Forma:SolidPeso molecular:396.46Clofenamide
CAS:Clofenamide is a low-ceiling sulfonamide diuretic.Fórmula:C6H7ClN2O4S2Cor e Forma:SolidPeso molecular:270.71hCAII-IN-2
CAS:hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.Fórmula:C25H18ClN5O4SCor e Forma:SolidPeso molecular:519.96hCAXII-IN-5
CAS:hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI & II >10000, hCAIX 286.1, hCAXII 1.0 nM.Fórmula:C23H22N2O4Cor e Forma:SolidPeso molecular:390.43LP-533401
CAS:LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.Fórmula:C27H22F4N4O3Pureza:98%Cor e Forma:SolidPeso molecular:526.48CK1 δ/CSNK1D Protein, Human, Recombinant (Baculovirus, His)
Expression system: Baculovirus
Length: 1-415, Full Length
Activity: Not TestedPureza:85%Cor e Forma:Odour Lyophilized PowderRef: TM-TMPH-03771
1mg8.803,00€5µg947,00€10µg1.598,00€20µg2.712,00€50µg3.520,00€100µg4.337,00€200µg5.358,00€500µg7.113,00€Disulfamide
CAS:Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.Fórmula:C7H9ClN2O4S2Pureza:98.65%Cor e Forma:SolidPeso molecular:284.74hCAXII-IN-1
CAS:hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.Fórmula:C20H17NO5Cor e Forma:SolidPeso molecular:351.35Quinethazone
CAS:Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.Fórmula:C10H12ClN3O3SCor e Forma:Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Peso molecular:289.74hCAIX-IN-10
CAS:"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."Fórmula:C28H21N3O3SCor e Forma:SolidPeso molecular:479.55hCAI/II-IN-3
CAS:"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."Fórmula:C16H18N4O4S2Cor e Forma:SolidPeso molecular:394.47hCAIX-IN-6
CAS:6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.Fórmula:C18H12N2O4SCor e Forma:SolidPeso molecular:352.36Carbonic anhydrase inhibitor 7
CAS:Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.Fórmula:C23H17N3O5SCor e Forma:SolidPeso molecular:447.46SU 10603
CAS:SU 10603 is a specific inhibitor of 17α-hydroxylase (also known as CYP17A1 and P450c17) used to study steroid hormone synthesis.Fórmula:C15H12ClNOPureza:99.93% - 99.96%Cor e Forma:SolidPeso molecular:257.72
