Enzima
Os inibidores de enzimas são moléculas que se ligam a enzimas e diminuem sua atividade. Esses inibidores são amplamente utilizados em pesquisas para estudar a cinética enzimática, regulação e o papel de enzimas específicas nas vias metabólicas. Os inibidores de enzimas também são cruciais no desenvolvimento de medicamentos, pois muitos agentes terapêuticos funcionam inibindo enzimas envolvidas em processos patológicos. Ao direcionar enzimas, esses inibidores podem modular vias bioquímicas e oferecer tratamentos potenciais para várias doenças. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de enzimas de alta qualidade para apoiar sua pesquisa em bioquímica, farmacologia e descoberta de medicamentos.
Subcategorias de "Enzima"
- Anidrase carbónica(197 produtos)
- Hidroxilase(36 produtos)
- MPO(2 produtos)
- Redutase(51 produtos)
- Tirosinase(71 produtos)
Foram encontrados 3621 produtos de "Enzima"
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Carbonic anhydrase inhibitor 4
CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.Fórmula:C21H18N2O4SCor e Forma:SolidPeso molecular:394.44Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].Fórmula:C15H17N3O3SCor e Forma:SolidPeso molecular:319.38CA IX-IN-1
CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.Fórmula:C16H22N4O8SCor e Forma:SolidPeso molecular:430.43Carbonic anhydrase inhibitor 10
CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.Fórmula:C14H17N5O3SCor e Forma:SolidPeso molecular:335.38hCAII-IN-5
CAS:hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].Fórmula:C29H18N2O7Cor e Forma:SolidPeso molecular:506.46hCA VB-IN-1
hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].Fórmula:C9H13N3O4SCor e Forma:SolidPeso molecular:259.28Carbonic anhydrase inhibitor 5
Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.Fórmula:C24H20ClN3O3SCor e Forma:SolidPeso molecular:465.95Carbonic anhydrase inhibitor 9
Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.Fórmula:C22H20BrN5O4SCor e Forma:SolidPeso molecular:530.39NSC 828467
NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).Fórmula:C21H19N9O2SCor e Forma:SolidPeso molecular:461.5β-Glucuronidase/hCAII-IN-1
CAS:β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50Fórmula:C30H21NO9Cor e Forma:SolidPeso molecular:539.49CAII-IN-2
CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.Fórmula:C18H19BrN4SCor e Forma:SolidPeso molecular:403.34Carbonic anhydrase inhibitor 8
R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).Fórmula:C20H25N3O4SCor e Forma:SolidPeso molecular:403.5hCA XII/II/IX-IN-1
hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.Fórmula:C25H34N4O7SCor e Forma:SolidPeso molecular:534.63CA IX-IN-3
CAS:CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.Fórmula:C21H19N5O4S2Cor e Forma:SolidPeso molecular:469.5374-Acetylphenylboronic acid
CAS:4-Acetylphenylboronic acid acts as an effective inhibitor targeting carbonic anhydrase II (CAII), displaying inhibitory concentrations (IC50) of 246 μM for bovine CAII (bCA II) and 281.40 μM for human CAII (hCA II).Fórmula:C8H9BO3Cor e Forma:SolidPeso molecular:163.97Tyrosinase-IN-20
CAS:Tyrosinase-IN-20 (compound 6a) acts as a potent Tyrosinase inhibitor, demonstrating an IC 50 value of 28.50 μM [1].Fórmula:C17H18N2O2SCor e Forma:SolidPeso molecular:314.4Sulclamide
CAS:Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].Fórmula:C7H7ClN2O3SCor e Forma:SolidPeso molecular:234.66Tyrosinase-IN-29
CAS:Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.Fórmula:C10H9NO2Cor e Forma:SolidPeso molecular:175.18O-Desmethyl Brinzolamide hydrochloride
CAS:O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].Fórmula:C11H20ClN3O5S3Cor e Forma:SolidPeso molecular:405.94hCAI/II/XII-IN-1
CAS:hCAI/II/XII-IN-1 (compound 7) is an inhibitor of human carbonic anhydrases hCAI, hCAII, and hCAXII, with Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM.Fórmula:C12H12N2O2SCor e Forma:SolidPeso molecular:248.301
