Tirosinase
A tirosinase é uma enzima envolvida na síntese de melanina, o pigmento responsável pela cor da pele, cabelo e olhos. A tirosinase catalisa a oxidação da tirosina em DOPA e, subsequentemente, em DOPAquinona, que leva à formação de melanina. Inibidores de tirosinase são de interesse no tratamento de distúrbios de hiperpigmentação e também são usados na indústria cosmética para reduzir a pigmentação da pele. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosinase e reagentes de alta qualidade para apoiar sua pesquisa em dermatologia, enzimologia e ciência cosmética.
Foram encontrados 76 produtos para "Tirosinase".
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BENZYLACETONE
CAS:Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties.Fórmula:C10H12OPureza:98.79%Cor e Forma:Colourless LiquidPeso molecular:148.2(R)-Trolox
CAS:(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.Fórmula:C14H18O4Pureza:99.88%Cor e Forma:SolidPeso molecular:250.29Tyrosinase
CAS:Copper-containing enzyme that catalyzes the first step in the synthesis of melanin
Cor e Forma:PowderTyrosinase
CAS:Tyrosinase (EC 1.14.18.1) is an enzyme that oxydises phenol derivatives (e.g. tyrosine, dopamine). One unit of tyrosinase dissolved in 3mL reaction mixture will cause the absorbance at 280nm to increase by 0.001 in the presence of L-tyrosine at pH 6.5 and 25 °C. L-tyrosine is available here.Lyophilized, from mushroom. Activity ≥1000 unit/mgCor e Forma:Powder3,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Fórmula:C7H10BrNO2Pureza:98.49%Cor e Forma:SolidPeso molecular:220.06ER 27319 maleate
CAS:Selective inhibitor of Syk kinaseFórmula:C22H24N2O5Pureza:98.45%Cor e Forma:Yellow SolidPeso molecular:396.44Tyrosinase-IN-7
CAS:Tyrosinase-IN-7 is a small-molecule tyrosinase inhibitor (IC50 1.57 μM) that suppresses melanin activity and cell growth with low cytotoxicity.Fórmula:C15H10O5Pureza:99%Cor e Forma:Orange SolidPeso molecular:270.24Tyrosinase-IN-2
CAS:Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.Fórmula:C8H8N4O2SPureza:99.78%Cor e Forma:SolidPeso molecular:224.24Tyrosinase-IN-37
CAS:Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.Fórmula:C12H12N6SCor e Forma:SolidPeso molecular:272.33Plodicitinib
CAS:Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.Fórmula:C19H22FN7O2Cor e Forma:SolidPeso molecular:399.422Tyrosinase-IN-35
CAS:Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.Fórmula:C17H15N5OSCor e Forma:SolidPeso molecular:337.40Isobutylamido thiazolyl resorcinol
CAS:Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.Fórmula:C13H14N2O3SCor e Forma:SolidPeso molecular:278.33Tyrosinase-IN-33
CAS:Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.Fórmula:C19H17NS2Cor e Forma:SolidPeso molecular:323.48Tyrosinase-IN-39
Tyrosinase-IN-39 (compound 5r) is a competitive inhibitor of tyrosinase, with an IC50 of 6.4 μM, and is used in the study of skin diseases.Fórmula:C23H19N5O4S2Cor e Forma:SolidPeso molecular:493.56Tyrosinase-IN-20
CAS:Tyrosinase-IN-20 (compound 6a) acts as a potent Tyrosinase inhibitor, demonstrating an IC 50 value of 28.50 μM [1].Fórmula:C17H18N2O2SCor e Forma:SolidPeso molecular:314.4Tyrosinase-IN-29
CAS:Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.Fórmula:C10H9NO2Cor e Forma:SolidPeso molecular:175.18
