Hidroxilase
As hidroxilases são uma classe de enzimas que catalisam a hidroxilação de substratos, frequentemente adicionando grupos hidroxila (-OH) a posições específicas dentro das moléculas. Estas enzimas estão envolvidas em uma ampla variedade de vias bioquímicas, incluindo a síntese de hormônios, processos de desintoxicação e o metabolismo de drogas. Inibidores e ativadores de hidroxilases são ferramentas valiosas na pesquisa sobre distúrbios metabólicos, metabolismo de drogas e regulação hormonal. Na CymitQuimica, oferecemos uma seleção de reagentes de hidroxilases de alta qualidade para apoiar sua pesquisa em bioquímica, farmacologia e regulação metabólica.
Foram encontrados 30 produtos de "Hidroxilase"
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p-Ethynylphenylalanine hydrochloride
CAS:<p>p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].</p>Fórmula:C11H12ClNO2Pureza:99.03%Cor e Forma:SolidPeso molecular:225.67Fenclonine
CAS:<p>Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.</p>Fórmula:C9H10ClNO2Pureza:98.81% - >99.99%Cor e Forma:Crystals From Methanol White SolidPeso molecular:199.63ACT-678689
CAS:<p>ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].</p>Fórmula:C23H22ClFN6O4S2Pureza:99.46%Cor e Forma:SolidPeso molecular:565.04Telotristat ethyl
CAS:<p>Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.</p>Fórmula:C27H26ClF3N6O3Pureza:98% - 99.89%Cor e Forma:White SolidPeso molecular:574.98TPT-004
<p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>Cor e Forma:Odour SolidIOX2-NH2-1
CAS:<p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>Fórmula:C19H17N3O5Pureza:98.77% - 99.91%Cor e Forma:SoildPeso molecular:367.36TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Fórmula:C21H18N6O4SCor e Forma:SolidPeso molecular:450.47GSK180
CAS:<p>GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.</p>Fórmula:C10H7Cl2NO4Cor e Forma:SolidPeso molecular:276.07Cuprizone
CAS:<p>Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.</p>Fórmula:C14H22N4O2Pureza:≥98%Cor e Forma:SolidPeso molecular:278.35Nepicastat hydrochloride
CAS:<p>Nepicastat hydrochloride (RS-25560-197 hydrochloride) is a selective, orally active, dopamine-beta-hydroxylase inhibitor that crosses the blood-brain barrier.</p>Fórmula:C14H15F2N3S·HClPureza:98.35% - 99.74%Cor e Forma:SolidPeso molecular:331.81FG-2216
CAS:<p>FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.</p>Fórmula:C12H9ClN2O4Pureza:97.1% - >99.99%Cor e Forma:SolidPeso molecular:280.66Tetrahydropapaverine hydrochloride
CAS:<p>Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.</p>Fórmula:C20H26ClNO4Pureza:99.08%Cor e Forma:White Crystal PowderPeso molecular:379.878Telotristat
CAS:<p>Telotristat, active metabolite of LX1606, is an oral tryptophan hydroxylase inhibitor with potential antiserotonergic effects.</p>Fórmula:C25H22ClF3N6O3Pureza:99.70%Cor e Forma:SolidPeso molecular:546.93Ro 61-8048
CAS:Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.Fórmula:C17H15N3O6S2Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:421.45p-Fluoro-L-phenylalanine
CAS:<p>p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.</p>Fórmula:C9H10FNO2Pureza:99.63%Cor e Forma:White To Off-White PowderPeso molecular:183.18Telotristat Etiprate
CAS:<p>Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.</p>Fórmula:C27H26ClF3N6O3·C9H9NO3Pureza:99.21% - 99.83%Cor e Forma:White SolidPeso molecular:754.15Mildronate
CAS:<p>Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine</p>Fórmula:C6H14N2O2Pureza:99.94%Cor e Forma:White Crystalline PowderPeso molecular:146.19TETRAHYDROPIPERINE
CAS:<p>Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.</p>Fórmula:C17H23NO3Pureza:98.04% - 99.61%Cor e Forma:Off-White Low Melting Solid With Characteristic OdourPeso molecular:289.37Nepicastat
CAS:<p>Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.</p>Fórmula:C14H15F2N3SCor e Forma:SolidPeso molecular:295.35Guanoclor
CAS:<p>Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.</p>Fórmula:C9H12Cl2N4OPureza:98.79%Cor e Forma:SolidPeso molecular:263.12
