NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 406 produtos de "NF-κB"
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Guaiacol
CAS:Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.
Fórmula:C7H8O2Pureza:99.95%Cor e Forma:Colourless To Pale Yellow Solid CrystallinePeso molecular:124.14SN50 acetate (213546-53-3 free base)
SN50 acetate is a cell permeable inhibitor of NF-κB translocation.Fórmula:C131H234N36O31SPureza:99.86%Cor e Forma:SolidPeso molecular:2841.55Sodium salicylate
CAS:Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Fórmula:C7H5NaO3Pureza:99.36% - 99.92%Cor e Forma:White Solid AmorphousPeso molecular:160.11DRI-C21045
CAS:Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).Fórmula:C32H24N2O7SPureza:97.20%Cor e Forma:SolidPeso molecular:580.61Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Fórmula:C20H17FO3SPureza:99.09% - 99.15%Cor e Forma:Yellow SolidPeso molecular:356.414-Hydroxychalcone
CAS:4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.Fórmula:C15H12O2Pureza:99.75%Cor e Forma:Yellow PowderPeso molecular:224.25Indacaterol maleate
CAS:Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.Fórmula:C28H32N2O7Pureza:99.03% - 99.67%Cor e Forma:SolidPeso molecular:508.56Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!Fórmula:C15H24O5Pureza:98% - 99.41%Cor e Forma:White SolidPeso molecular:284.35Nimbolide
CAS:Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.Fórmula:C27H30O7Pureza:95.84% - 99.4%Cor e Forma:SolidPeso molecular:466.52Ref: TM-T16324
1mg67,00€5mg167,00€10mg289,00€25mg595,00€50mg820,00€100mg1.108,00€200mg1.440,00€1mL*10mM (DMSO)180,00€TBK1/IKKε-IN-2
CAS:TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.Fórmula:C26H27N5O3Pureza:98.89%Cor e Forma:SolidPeso molecular:457.52Ref: TM-T15559
1mg87,00€5mg178,00€10mg289,00€25mg462,00€50mg625,00€100mg802,00€1mL*10mM (DMSO)178,00€Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Fórmula:C18H14N4O5SPureza:98.00% - 99.28%Cor e Forma:Minute Brownish-Yellow CrystalsPeso molecular:398.39Ergolide
CAS:Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.Fórmula:C17H22O5Pureza:99.64%Cor e Forma:SolidPeso molecular:306.35Ref: TM-T13686
1mg71,00€5mg139,00€10mg230,00€25mg374,00€50mg520,00€100mg697,00€1mL*10mM (DMSO)166,00€CDDO-dhTFEA
CAS:CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.Fórmula:C33H45F3N2O3Pureza:95.61% - 99.59%Cor e Forma:SolidPeso molecular:574.72Ref: TM-T13604
1mg70,00€2mg92,00€5mg153,00€10mg255,00€25mg512,00€50mg738,00€100mg1.035,00€500mg2.062,00€1mL*10mM (DMSO)187,00€Theophylline
CAS:Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFórmula:C7H8N4O2Pureza:99.65% - 99.98%Cor e Forma:White Solid PowderPeso molecular:180.16Sinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Fórmula:C19H24ClNO4Pureza:99.43%Cor e Forma:SolidPeso molecular:365.85Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Fórmula:C14H22N2O·HCl·H2OPureza:99.95%Cor e Forma:SolidPeso molecular:288.82Theophylline monohydrate
CAS:Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calciumFórmula:C7H8N4O2·H2OPureza:99.78%Cor e Forma:SolidPeso molecular:198.18Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFórmula:C21H18O11Pureza:90.08% - 99.32%Cor e Forma:Yellow PowderPeso molecular:446.36Ref: TM-T2775
1g80,00€2g102,00€5g152,00€50mg34,00€100mg49,00€200mg49,00€500mg55,00€1mL*10mM (DMSO)50,00€DMAPT
CAS:DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in acute myeloid leukemia cells.Fórmula:C17H27NO3Pureza:99.91%Cor e Forma:SolidPeso molecular:293.4IMD-0560
CAS:IMD-0560 is a novel inhibitor of IκB kinase β.Fórmula:C15H8BrF6NO2Pureza:99.51%Cor e Forma:SolidPeso molecular:428.12
