NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 387 produtos de "NF-κB"
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IKKγ NBD Inhibitory Peptide acetate
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.
Pureza:99.15%Cor e Forma:SolidPeso molecular:N/ARef: TM-TP1615L
1mg131,00€2mg173,00€5mg255,00€10mg374,00€25mg625,00€50mg890,00€100mg1.206,00€500mg2.422,00€Vamorolone
CAS:Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.Fórmula:C22H28O4Pureza:99.54%Cor e Forma:SolidPeso molecular:356.46Ref: TM-T17217
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg105,00€25mg178,00€50mg281,00€100mg421,00€200mg605,00€Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Fórmula:C33H40O19Pureza:98.78% - 99.13%Cor e Forma:SolidPeso molecular:740.66Polygalasaponin F
CAS:Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.Fórmula:C53H86O23Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:1091.24Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Fórmula:C17H26O4Pureza:97.07% - 99.88%Cor e Forma:SolidPeso molecular:294.39Triptolide
CAS:Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.Fórmula:C20H24O6Pureza:97.19% - 99.97%Cor e Forma:White To Off-White SolidPeso molecular:360.40Ref: TM-T2179
1mg39,00€2mg52,00€1mL*10mM (DMSO)75,00€5mg95,00€10mg123,00€25mg225,00€50mg315,00€100mg444,00€Barlerin
CAS:Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose deprivation-induced injuryFórmula:C19H28O12Pureza:99.83% - ≥95%Cor e Forma:SolidPeso molecular:448.42Ref: TM-T5S1632
1mg38,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg109,00€25mg231,00€50mg335,00€100mg505,00€TBK1/IKKε-IN-5
CAS:TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).Fórmula:C28H31N7O3Pureza:98.77%Cor e Forma:SolidPeso molecular:513.59Ref: TM-T7951
1mg88,00€5mg182,00€1mL*10mM (DMSO)224,00€10mg269,00€25mg429,00€50mg587,00€100mg837,00€200mg1.125,00€Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Fórmula:C17H16O4Pureza:99.87% - ≥95%Cor e Forma:SolidPeso molecular:284.31Tyrosol
CAS:Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present mostFórmula:C8H10O2Pureza:99.24% - 99.86%Cor e Forma:SolidPeso molecular:138.16PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Fórmula:C22H26N4O3Pureza:98.82%Cor e Forma:SolidPeso molecular:394.47SM-7368
CAS:The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.Fórmula:C10H5ClN4O5SPureza:99.64%Cor e Forma:SolidPeso molecular:328.69Ref: TM-T22115
5mg44,00€1mL*10mM (DMSO)52,00€10mg71,00€25mg128,00€50mg178,00€100mg268,00€200mg389,00€Tomatidine
CAS:Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.
Fórmula:C27H45NO2Pureza:99.94% - 99.98%Cor e Forma:SolidPeso molecular:415.6511-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Fórmula:C30H46O4Pureza:99.68%Cor e Forma:SolidPeso molecular:470.68Ref: TM-TN1182
1mg57,00€5mg130,00€1mL*10mM (DMSO)133,00€10mg200,00€25mg338,00€50mg497,00€100mg710,00€Maslinic acid
CAS:Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.Fórmula:C30H48O4Pureza:98.1% - 99.98%Cor e Forma:SolidPeso molecular:472.70Malachite green oxalate
CAS:Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.Fórmula:C23H25N2·C2HO4C2H2O4Cor e Forma:Dark Green Crystals With A Metallic LusterPeso molecular:463.51Sarsasapogenin
CAS:Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.Fórmula:C27H44O3Pureza:90% - 99.73%Cor e Forma:White Or Off-Withe PowderPeso molecular:416.64Obtusifolin
CAS:Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.Fórmula:C16H12O5Pureza:99.78% - 99.99%Cor e Forma:SolidPeso molecular:284.26Ref: TM-T4S0969
1mg66,00€5mg177,00€1mL*10mM (DMSO)177,00€10mg264,00€25mg447,00€50mg623,00€100mg883,00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Fórmula:C38H44N2O6Pureza:98.81% - 99.65%Cor e Forma:SolidPeso molecular:624.77
