NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 444 produtos de "NF-κB"
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Betulinic acid
CAS:<p>Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.</p>Fórmula:C30H48O3Pureza:99.12% - 99.7%Cor e Forma:White Crystalline PowderPeso molecular:456.7Indacaterol
CAS:<p>Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.</p>Fórmula:C24H28N2O3Pureza:99.96%Cor e Forma:SolidPeso molecular:392.49Rucaparib monocamsylate
CAS:<p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>Fórmula:C29H34FN3O5SPureza:99.82%Cor e Forma:SolidPeso molecular:555.66Tryptanthrin
CAS:<p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>Fórmula:C15H8N2O2Pureza:99.64% - 99.94%Cor e Forma:SolidPeso molecular:248.24Sauchinone
CAS:<p>Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.</p>Fórmula:C20H20O6Pureza:>99.99%Cor e Forma:SolidPeso molecular:356.37GSK547
CAS:<p>GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.</p>Fórmula:C20H18F2N6OPureza:99.17%Cor e Forma:SolidPeso molecular:396.39Sanggenon C
CAS:<p>Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.</p>Fórmula:C40H36O12Pureza:97.76% - 99.76%Cor e Forma:SolidPeso molecular:708.71HOMOPLANTAGININ
CAS:<p>Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows</p>Fórmula:C22H22O11Pureza:97.63% - 99.66%Cor e Forma:SolidPeso molecular:462.4SC75741
CAS:<p>SC75741 is a potent P65 inhibitor with IC50 of 200 nM</p>Fórmula:C29H23N7O2S2Pureza:99.44% - 99.54%Cor e Forma:SolidPeso molecular:565.67Sulforaphene
CAS:<p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>Fórmula:C6H9NOS2Pureza:97.55% - 99.19%Cor e Forma:Slightly Yellowish LiquidPeso molecular:175.27Ginsenoside Rg5
CAS:<p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>Fórmula:C42H70O12Pureza:98% - 99.65%Cor e Forma:SolidPeso molecular:767WAY-169916
CAS:<p>WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.</p>Fórmula:C17H13F3N2O2Pureza:98.63% - 98.64%Cor e Forma:SolidPeso molecular:334.29Astilbin
CAS:<p>Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.</p>Fórmula:C21H22O11Pureza:97% - 99.86%Cor e Forma:White PowderPeso molecular:450.39Praeruptorin A
CAS:<p>Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin</p>Fórmula:C21H22O7Pureza:99.63% - 99.65%Cor e Forma:SolidPeso molecular:386.4Tenuigenin
CAS:<p>Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.</p>Fórmula:C30H45ClO6Pureza:98.9% - 99.53%Cor e Forma:SolidPeso molecular:537.13Tectochrysin
CAS:<p>Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.</p>Fórmula:C16H12O4Pureza:99.26%Cor e Forma:SolidPeso molecular:268.26INH14
CAS:<p>INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).</p>Fórmula:C15H16N2OPureza:95.41%Cor e Forma:SolidPeso molecular:240.3Picroside II
CAS:<p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>Fórmula:C23H28O13Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:512.46Phorbol 12-myristate 13-acetate
CAS:<p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>Fórmula:C36H56O8Pureza:98.55% - >99.99%Cor e Forma:White To Off-White SolidPeso molecular:616.83Handelin
CAS:<p>Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.</p>Fórmula:C32H40O8Pureza:99.02% - 99.345%Cor e Forma:SolidPeso molecular:552.66
