NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 389 produtos de "NF-κB"
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Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Fórmula:C38H44N2O6Pureza:98.81% - 99.65%Cor e Forma:SolidPeso molecular:624.77Gossypin
CAS:Gossypin exhibits multiple medicinal properties and inhibits NF-kappaB, reducing inflammation, cancer growth, and angiogenesis.Fórmula:C21H20O13Pureza:97.57% - 98.97%Cor e Forma:SolidPeso molecular:480.38Aconine
CAS:1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.Fórmula:C25H41NO9Pureza:99.61% - 99.93%Cor e Forma:SolidPeso molecular:499.59Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Fórmula:C30H48O6Pureza:98.80% - 99.69%Cor e Forma:SolidPeso molecular:504.70Delanzomib
CAS:Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Fórmula:C21H28BN3O5Pureza:95.52% - 99.46%Cor e Forma:SolidPeso molecular:413.28Ref: TM-T6027
1mg46,00€1mL*10mM (DMSO)95,00€5mg96,00€10mg140,00€25mg274,00€50mg439,00€100mg660,00€200mg917,00€Deoxyelephantopin
CAS:Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.Fórmula:C19H20O6Pureza:99.6% - 99.71%Cor e Forma:SolidPeso molecular:344.36Aristolochic acid A
CAS:Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort family of plants.Fórmula:C17H11NO7Pureza:99.85% - 99.97%Cor e Forma:Yellow PowderPeso molecular:341.27Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFórmula:C9H9NOPureza:98.59% - >99.99%Cor e Forma:SolidPeso molecular:147.17(S)-(+)-Ibuprofen
CAS:(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).Fórmula:C13H18O2Pureza:99.51% - 99.86%Cor e Forma:Colourless Crystalline SolidPeso molecular:206.28GSK-872
CAS:GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity and inhibits kinase activity.
Fórmula:C19H17N3O2S2Pureza:99.87% - 99.94%Cor e Forma:SolidPeso molecular:383.49MnTBAP chloride
CAS:MnTBAP chloride: SOD mimetic, peroxynitrite scavenger, halves SOD-E. coli growth time, anti-inflammatory, may aid CKD research.Fórmula:C48H25ClMnN4O8Cor e Forma:SolidPeso molecular:876.133'-Sialyllactose sodium
CAS:3'-Sialyllactose sodium is a prebiotic with anti-inflammatory activity that maintains immune homeostasis and can be used to study inflammation.Fórmula:C23H38NNaO19Pureza:>99.99%Cor e Forma:SolidPeso molecular:655.53Tamtuvetmab
CAS:Tamtuvetmab (AT-005), a caninised version of blontuvetmab targeting CD52, enhances progression-free survival (PFS) and demonstrates in vivo efficacy forCor e Forma:LiquidGatralimab
CAS:Gatralimab (anti-CD52 mAb) shows successful lymphocyte depletion & repopulation in Phase 1, supporting its study for relapsing MS.Pureza:95%Cor e Forma:LiquidPeso molecular:~150 kDa1,3-Dibenzyl-5-fluorouracil
CAS:1,3-Dibenzyl-5-fluorouracil is a chemical inhibitor that suppresses the formation of osteoclasts, functioning by downregulating the signaling pathways of nuclear factor κB ligand receptor activator (Receptor activator of NF-κB ligand, RANKL) and macrophage colony-stimulating factor (M-CSF). This compound is used in the research of metabolic bone diseases.Fórmula:C18H15FN2O2Cor e Forma:SolidPeso molecular:310.32Boserolimab
CAS:Boserolimab, Humanized anti-CD27 agonistic mAb, blocks CD70 binding to CD27, used for lung cancer research.Pureza:95% - 95%Cor e Forma:LiquidKamebakaurin
CAS:Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.Fórmula:C20H30O5Pureza:98.05%Cor e Forma:SolidPeso molecular:350.45E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Fórmula:C21H30O6Pureza:99.52%Cor e Forma:SolidPeso molecular:378.46Bay 65-1942 free base
CAS:Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.Fórmula:C22H25N3O4Pureza:98%Cor e Forma:SolidPeso molecular:395.45ABD-350
CAS:ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.Fórmula:C19H22F2O2Cor e Forma:SolidPeso molecular:320.37
