NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 444 produtos de "NF-κB"
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HS-1371
CAS:<p>HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.</p>Fórmula:C24H24N4OPureza:98%Cor e Forma:SolidPeso molecular:384.47Okanin
CAS:<p>Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.</p>Fórmula:C15H12O6Pureza:95.19% - 99.4%Cor e Forma:SolidPeso molecular:288.25Schisantherin A
CAS:<p>Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.</p>Fórmula:C30H32O9Pureza:98% - 99.989Cor e Forma:SolidPeso molecular:536.57Necrostatin 2 racemate
CAS:<p>Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.</p>Fórmula:C13H12ClN3O2Pureza:98% - 99.5%Cor e Forma:SolidPeso molecular:277.71Esculentoside H
CAS:<p>Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.</p>Fórmula:C48H76O21Pureza:98.04% - 99.3%Cor e Forma:SolidPeso molecular:989.1Isoliquiritin apioside
CAS:<p>Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.</p>Fórmula:C26H30O13Pureza:98.84% - 99.27%Cor e Forma:SolidPeso molecular:550.51Ginsenoside Re
CAS:<p>Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.</p>Fórmula:C48H82O18Pureza:99.12% - >99.99%Cor e Forma:White PowderPeso molecular:947.15Suberosin
CAS:<p>Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.</p>Fórmula:C15H16O3Pureza:97.08% - 99.26%Cor e Forma:SolidPeso molecular:244.29NDMC101
CAS:<p>NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.</p>Fórmula:C13H9ClFNO2Pureza:99.89%Cor e Forma:SolidPeso molecular:265.67IRAK4-IN-1
CAS:<p>IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.</p>Fórmula:C19H23N5OPureza:98.18% - 99.85%Cor e Forma:SolidPeso molecular:337.42BMS-345541 hydrochloride
CAS:<p>BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).</p>Fórmula:C14H18ClN5Pureza:99.13%Cor e Forma:SolidPeso molecular:291.78IKK 16
CAS:<p>IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.</p>Fórmula:C28H29N5OSPureza:98.76% - 99.61%Cor e Forma:SolidPeso molecular:483.63GSK2983559 active metabolite
CAS:<p>GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.</p>Fórmula:C21H22N4O4S2Pureza:97.07% - 99.57%Cor e Forma:SolidPeso molecular:458.55NF-κΒ activator 2
CAS:<p>NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.</p>Fórmula:C16H11FN2O3Pureza:98.12%Cor e Forma:SolidPeso molecular:298.27Eurycomalactone
CAS:<p>Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.</p>Fórmula:C19H24O6Pureza:99.48% - 99.87%Cor e Forma:SolidPeso molecular:348.39JSH-23
CAS:<p>JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.</p>Fórmula:C16H20N2Pureza:98.03% - 99.67%Cor e Forma:SolidPeso molecular:240.34GS143
CAS:<p>GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.</p>Fórmula:C28H19FN2O4Pureza:97.67%Cor e Forma:SolidPeso molecular:466.46Isodeoxyelephantopin
CAS:<p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>Fórmula:C19H20O6Pureza:99.88%Cor e Forma:SolidPeso molecular:344.36IKKγ NBD Inhibitory Peptide acetate
<p>IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.</p>Pureza:99.15%Cor e Forma:SolidPeso molecular:N/AVamorolone
CAS:<p>Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.</p>Fórmula:C22H28O4Pureza:99.54%Cor e Forma:SolidPeso molecular:356.46
