NF-κB
O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.
Foram encontrados 446 produtos de "NF-κB"
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Dehydroevodiamine
CAS:Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressantFórmula:C19H15N3OPureza:99.54%Cor e Forma:SolidPeso molecular:301.34Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Fórmula:C27H30O14Pureza:98.11% - 98.58%Cor e Forma:SolidPeso molecular:578.52Ginsenoside Rb1
CAS:Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.Fórmula:C54H92O23Pureza:99.12% - 99.76%Cor e Forma:SolidPeso molecular:1109.29GSK481
CAS:<p>GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.</p>Fórmula:C21H19N3O4Pureza:98.97%Cor e Forma:SolidPeso molecular:377.39Eclitasertib
CAS:<p>Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).</p>Fórmula:C19H18N6O3Pureza:99.85%Cor e Forma:SolidPeso molecular:378.38Damascenone
CAS:Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.Fórmula:C13H18OPureza:99.81%Cor e Forma:Colorless LiquidPeso molecular:190.28Ginsenoside Rd
CAS:<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Fórmula:C48H82O18Pureza:99.13% - 99.92%Cor e Forma:SolidPeso molecular:947.15WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Fórmula:C28H38O6Pureza:97.41% - 99.99%Cor e Forma:SolidPeso molecular:470.60Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Fórmula:C19H18FN3OPureza:98.24% - 99.80%Cor e Forma:SolidPeso molecular:323.362-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Fórmula:C15H12O2Pureza:99.6%Cor e Forma:SolidPeso molecular:224.252,5-Dihydroxyacetophenone
CAS:2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.Fórmula:C8H8O3Pureza:99.75%Cor e Forma:Yellow PowderPeso molecular:152.15Phellodendrine
CAS:Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.Fórmula:C20H24NO4Pureza:98.7% - 99.94%Cor e Forma:SolidPeso molecular:342.41Pyrrolidinedithiocarbamate ammonium
CAS:Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxideFórmula:C5H12N2S2Pureza:98% - >99.99%Cor e Forma:Off-White To Pale Yellow CrystalsPeso molecular:164.29IRAK inhibitor 6
CAS:IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).Fórmula:C20H20N4O3SPureza:99.44%Cor e Forma:SolidPeso molecular:396.46PTP1B-IN-1
CAS:PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)Fórmula:C8H8N2O3SPureza:99.27%Cor e Forma:SolidPeso molecular:212.23Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Fórmula:C20H34OPureza:99.17% - ≥98%Cor e Forma:SolidPeso molecular:290.48Necrostatin-34
CAS:<p>Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a</p>Fórmula:C18H16N4O2S2Pureza:98.66% - 98.8%Cor e Forma:SolidPeso molecular:384.48IMD-0354
CAS:IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.Fórmula:C15H8ClF6NO2Pureza:99.65% - 99.98%Cor e Forma:SolidPeso molecular:383.67Articaine
CAS:Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-Fórmula:C13H20N2O3SCor e Forma:SolidPeso molecular:284.37
