CymitQuimica logo
NF-κB

NF-κB

O fator nuclear kappa-light-chain-enhancer de células B ativadas (NF-κB) é um fator de transcrição que regula a expressão de genes envolvidos em respostas imunes, inflamação, sobrevivência celular e proliferação. O NF-κB é ativado em resposta a vários estímulos, incluindo citocinas, patógenos e sinais de estresse. A desregulação da sinalização do NF-κB está associada a doenças inflamatórias crônicas, câncer e distúrbios autoimunes. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores da via NF-κB para apoiar sua pesquisa em inflamação, oncologia e regulação imunológica.

Foram encontrados 443 produtos de "NF-κB"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • HSR1304
    Targetmol
    + Info

    HSR1304

    CAS:
    <p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>
    Fórmula:C24H21ClN2O3
    Cor e Forma:Solid
    Peso molecular:420.89

    Ref: TM-T62239

  • ABD-350
    Targetmol
    + Info

    ABD-350

    CAS:
    <p>ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.</p>
    Fórmula:C19H22F2O2
    Cor e Forma:Solid
    Peso molecular:320.37

    Ref: TM-T26513

  • MHY884
    Targetmol
    + Info

    MHY884

    CAS:
    <p>MHY884 inhibits tyrosinase and UVB-triggered NF-κB activation by reducing oxidative stress.</p>
    Fórmula:C15H14ClNO3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:323.79

    Ref: TM-T25807

  • IT-901
    Targetmol
    + Info

    IT-901

    CAS:
    <p>IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.</p>
    Fórmula:C17H14N2O4S
    Pureza:98.06%
    Cor e Forma:Solid
    Peso molecular:342.37

    Ref: TM-T15601

  • Asperbisabolane L
    Targetmol
    + Info

    Asperbisabolane L

    <p>Asperbisabolane L, a sesquiterpenoid, combats inflammation by blocking NF-κB signaling and NO in BV-2 cells.</p>
    Fórmula:C12H14O3
    Cor e Forma:Solid
    Peso molecular:206.24

    Ref: TM-T72646

  • CID-2858522
    Targetmol
    + Info

    CID-2858522

    CAS:
    <p>CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).</p>
    Fórmula:C28H39N3O3
    Pureza:96.12%
    Cor e Forma:Solid
    Peso molecular:465.63

    Ref: TM-TQ0305

  • IMD-biphenylB
    Targetmol
    + Info

    IMD-biphenylB

    CAS:
    <p>IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.</p>
    Fórmula:C35H33N5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:571.67

    Ref: TM-T72870

  • 1-Dehydro-[10]-gingerdione
    Targetmol
    + Info

    1-Dehydro-[10]-gingerdione

    CAS:
    <p>1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.</p>
    Fórmula:C21H30O4
    Cor e Forma:Solid
    Peso molecular:346.46

    Ref: TM-T72208

  • Bay 65-1942 free base
    Targetmol
    + Info

    Bay 65-1942 free base

    CAS:
    Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
    Fórmula:C22H25N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:395.45

    Ref: TM-T10472L

  • TRAF-STOP inhibitor 6877002
    Targetmol
    + Info

    TRAF-STOP inhibitor 6877002

    CAS:
    <p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>
    Fórmula:C17H17NO
    Pureza:99.76%
    Cor e Forma:Solid
    Peso molecular:251.32

    Ref: TM-T17157

  • BAY32-5915
    Targetmol
    + Info

    BAY32-5915

    CAS:
    <p>BAY32-5915 is a selective inhibitor of IKKalpha.</p>
    Fórmula:C10H7NO3
    Pureza:96.48% - 97%
    Cor e Forma:Yellow Crystalline Powder
    Peso molecular:189.17

    Ref: TM-T20770

  • DHMEQ racemate
    Targetmol
    + Info

    DHMEQ racemate

    CAS:
    <p>DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.</p>
    Fórmula:C13H11NO5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:261.23

    Ref: TM-T11018

  • HE 3286
    Targetmol
    + Info

    HE 3286

    CAS:
    <p>Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.</p>
    Fórmula:C21H30O3
    Cor e Forma:Solid
    Peso molecular:330.46

    Ref: TM-T29013

  • IKK2-IN-4
    Targetmol
    + Info

    IKK2-IN-4

    CAS:
    <p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>
    Fórmula:C12H11N3O2S
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:261.3

    Ref: TM-T36524

  • RI-962
    Targetmol
    + Info

    RI-962

    CAS:
    <p>RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.</p>
    Fórmula:C28H28N6O2
    Pureza:99.39%
    Cor e Forma:Soild
    Peso molecular:480.56

    Ref: TM-T73493

  • NF-κB/PON1-IN-1
    Targetmol
    + Info

    NF-κB/PON1-IN-1

    CAS:
    <p>NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.</p>
    Fórmula:C20H16N6O4S2
    Cor e Forma:Solid
    Peso molecular:468.51

    Ref: TM-T63009

  • Anti-inflammatory agent 21
    Targetmol
    + Info

    Anti-inflammatory agent 21

    CAS:
    <p>Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.</p>
    Fórmula:C24H21FO6
    Cor e Forma:Solid
    Peso molecular:424.42

    Ref: TM-T62284

  • Xanthine oxidase-IN-6
    Targetmol
    + Info

    Xanthine oxidase-IN-6

    <p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>
    Fórmula:C29H34N2O15
    Cor e Forma:Solid
    Peso molecular:650.58

    Ref: TM-T72409

  • TNF-α-IN-18
    Targetmol
    + Info

    TNF-α-IN-18

    CAS:
    <p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>
    Fórmula:C16H7ClF2O4
    Pureza:99.77%
    Cor e Forma:Solid
    Peso molecular:336.67

    Ref: TM-T88696

  • APC-0576
    Targetmol
    + Info

    APC-0576

    CAS:
    <p>APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.</p>
    Fórmula:C23H27N3O3
    Cor e Forma:Solid
    Peso molecular:393.48

    Ref: TM-T69453