Receptor IL
Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.
Foram encontrados 118 produtos para "Receptor IL".
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Mirikizumab
CAS:Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).Pureza:98.41% (SEC-HPLC) - 98.41% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:144.26 kDaDupilumab
CAS:Dupilumab (REGN-668) is a systemic immunomodulator for AD.Pureza:95.00% - >99.2%Cor e Forma:White LiquidPeso molecular:149.8 kDaOlamkicept
CAS:Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.Pureza:95% - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:93.14 kDaImsidolimab
CAS:Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.Pureza:99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:146.71 kDaOlokizumab
CAS:Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.Pureza:99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.39 kDaPerakizumab
CAS:Perakizumab (RG4934) is a humanized monoclonal antibody targeting IL-17A, used in the study of psoriatic arthritis and other autoimmune diseases.Pureza:95.28% (SEC-HPLC) - 99.66% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.8 kDaSiltuximab
CAS:Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.Pureza:100% (SEC-HPLC) - >95% (SDS-PAGE); 100% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:144.98 kDaSarilumab
CAS:Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.Pureza:97.4%Cor e Forma:Transparent LiquidPeso molecular:144.12 kDaBriakinumab
CAS:Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.Pureza:>95%Cor e Forma:Transparent LiquidPeso molecular:143.86 kDaNidanilimab
CAS:Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.Pureza:> 95%Cor e Forma:Transparent LiquidPeso molecular:150 kDaIL-15-IN-1
CAS:IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).Fórmula:C30H36N6O4SPureza:99.16%Cor e Forma:SolidPeso molecular:576.71Ref: TM-T11634
1mg84,00€5mg161,00€1mL*10mM (DMSO)198,00€10mg245,00€25mg406,00€50mg572,00€100mg772,00€200mg1.035,00€Brodalumab
CAS:Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.Pureza:98.3%Cor e Forma:Transparent LiquidPeso molecular:144.06 kDa2-Benzothiazolamine
CAS:2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.Fórmula:C7H6N2SPureza:99.09% - 99.3%Cor e Forma:SolidPeso molecular:150.2Levilimab
CAS:Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.Pureza:97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.69 kDaRisankizumab
CAS:Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.Pureza:SDS-PAGE:95.3%;SEC-HPLC:98.3%Cor e Forma:Transparent LiquidPeso molecular:145.85 kDaTildrakizumab
CAS:Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.Pureza:> 95%Cor e Forma:Transparent LiquidPeso molecular:144.44 kDaEnokizumab
CAS:Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.Pureza:SDS-PAGE:95% SEC-HPLC:99.23%Cor e Forma:Transparent LiquidPeso molecular:145.98 kDaSpesolimab
CAS:Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.Pureza:> 95%Cor e Forma:Transparent LiquidPeso molecular:150 kDaOrdesekimab
CAS:Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.Pureza:> 95%Cor e Forma:Transparent LiquidPeso molecular:145.12 kDaElsilimomab
CAS:Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.Pureza:>95%Cor e Forma:Transparent LiquidPeso molecular:145.96 kDa
