Receptor IL
Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.
Foram encontrados 109 produtos de "Receptor IL"
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Vobarilizumab
CAS:Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.Pureza:>95%Cor e Forma:LiquidMirikizumab
CAS:Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).Pureza:98.41% (SEC-HPLC) - 98.41% (SEC-HPLC)Cor e Forma:LiquidEnokizumab
CAS:<p>Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.23%Cor e Forma:LiquidPeso molecular:145.98 kDaPerakizumab
CAS:<p>Perakizumab (RG4934) is a humanized monoclonal antibody targeting IL-17A, used in the study of psoriatic arthritis and other autoimmune diseases.</p>Pureza:95.28% (SEC-HPLC) - 99.66% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:145.4 (kDa)Imsidolimab
CAS:<p>Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.</p>Pureza:99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)Cor e Forma:LiquidBRD6989
CAS:BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.Fórmula:C16H16N4Pureza:99.43%Cor e Forma:SolidPeso molecular:264.33Brodalumab
CAS:<p>Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.</p>Pureza:98.3%Cor e Forma:LiquidPeso molecular:144.06 kDaLevilimab
CAS:<p>Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.</p>Pureza:97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:LiquidIL-15-IN-1
CAS:IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).Fórmula:C30H36N6O4SPureza:99.16%Cor e Forma:SolidPeso molecular:576.712-Benzothiazolamine
CAS:2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.Fórmula:C7H6N2SPureza:99.09% - 99.3%Cor e Forma:Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)Peso molecular:150.2Olamkicept
CAS:Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.Pureza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Cor e Forma:LiquidSarilumab
CAS:Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.Pureza:97.4%Cor e Forma:LiquidPeso molecular:144.12 kDaVunakizumab
CAS:<p>Vunakizumab is a humanized IgGκ monoclonal antibody targeting IL-17A, often linked to interleukin 22 to form Vunakizumab-IL22.</p>Pureza:95%Cor e Forma:LiquidYQ128
CAS:YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.Fórmula:C27H29ClN2O4S2Pureza:99.89%Cor e Forma:SolidPeso molecular:545.11PF-07038124 HCl
CAS:PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.Fórmula:C18H23BClNO4Pureza:97.34% - 99.13%Cor e Forma:SoildPeso molecular:363.64Ordesekimab
CAS:Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.12 kDaDupilumab
CAS:Dupilumab (REGN-668) is a systemic immunomodulator for AD.Pureza:95.00% - >99.2%Cor e Forma:LiquidSiltuximab
CAS:<p>Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.</p>Pureza:100% (SEC-HPLC) - > 95%Cor e Forma:LiquidPeso molecular:144.98 kDaIxekizumab
CAS:Ixekizumab: IgG4 antibody, neutralizes IL-17A (<3 pM), treats severe plaque psoriasis & arthritis.Pureza:98.86% (SEC-HPLC) - > 99.3% (SDS-PAGE); 95.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.2 kDaAbrezekimab
CAS:Abrezekimab (VR 942), a humanized antibody, blocks IL-13/IL-13Rα1, for asthma/lung disease study.Pureza:98.34% (SEC-HPLC) - 98.34% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:48.1 kDaBriakinumab
CAS:Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.Pureza:>95%Cor e Forma:LiquidElsilimomab
CAS:Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.Pureza:>95%Cor e Forma:LiquidXeligekimab
CAS:Xeligekimab (GR 1501) is a fully humanized monoclonal antibody that neutralizes IL-17A and has anti-inflammatory activity for the study of plaque psoriasis.Pureza:95%Cor e Forma:LiquidRisankizumab
CAS:Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.Pureza:SDS-PAGE:95.3%;SEC-HPLC:98.3%Cor e Forma:LiquidPeso molecular:145.85 kDaTildrakizumab
CAS:<p>Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:144.44 kDaOlokizumab
CAS:Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.Pureza:99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:LiquidBermekimab
CAS:Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.Cor e Forma:LiquidPeso molecular:145.45 kDaSpesolimab
CAS:Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.Pureza:> 95%Cor e Forma:LiquidPeso molecular:150 kDaNidanilimab
CAS:<p>Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.</p>Pureza:> 95%Cor e Forma:SoildPeso molecular:150 kDaStapokibart
CAS:<p>Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα, blocking IL-4Rα-mediated signaling. It is used in studies of atopic dermatitis.</p>Pureza:96.09% (SEC-HPLC) - 96.09% (SEC-HPLC)Cor e Forma:LiquidMacrophage-activating lipopeptide 2 TFA
Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist activates immune cell responses macrophages,Fórmula:C99H167N19O30S·xC2HF3O2Pureza:97.56%Cor e Forma:SolidPeso molecular:2135.56 (free base)CNTO 607
<p>CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.</p>Pureza:98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:Odour LiquidPascolizumab
CAS:<p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:147.18 kDaReslizumab
CAS:Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.Pureza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:N/ATemtokibart
CAS:<p>Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.</p>Cor e Forma:LiquidPeso molecular:145.5Daclizumab
CAS:<p>Daclizumab (Zenapax), a humanized antibody, blocks IL-2 by targeting CD25, used in multiple sclerosis.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Cor e Forma:LiquidPeso molecular:144.12 kDaPF-06342674
<p>PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.</p>Cor e Forma:LiquidPeso molecular:145.5kDaY13g dihydrochloride
<p>Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are</p>Fórmula:C16H25ClN2O4Pureza:97.81%Cor e Forma:SoildPeso molecular:344.83Guselkumab
CAS:Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.Pureza:SDS-PAGE:95% SEC-HPLC:98.97%Cor e Forma:LiquidPeso molecular:144.8 kDaMepolizumab
CAS:Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.Pureza:98% - 98%Cor e Forma:LiquidDectrekumab
CAS:<p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>Pureza:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Cor e Forma:LiquidTriphenyl phosphate
CAS:Triphenyl phosphate is an flame retardant and endocrine disruptor that activates MAO-A/ROS/NF-κB pathways, disrupting placental tryptophan metabolism.Fórmula:C18H15O4PPureza:99.94%Peso molecular:326.288ABzOH
CAS:<p>2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.</p>Fórmula:C12H10O2Pureza:99.43%Cor e Forma:SolidPeso molecular:186.21Torudokimab
<p>Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.</p>Pureza:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Cor e Forma:Odour LiquidCanakinumab
CAS:<p>Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).</p>Pureza:98.8%Cor e Forma:LiquidPeso molecular:145.18 kDaMyD88-IN-1
CAS:<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Fórmula:C23H24N6O7SPureza:>99.99%Cor e Forma:SoildPeso molecular:528.54Anti-inflammatory agent 42
CAS:Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.Fórmula:C20H12N2OSPureza:99.47%Cor e Forma:SolidPeso molecular:328.39Nosantine racemate
CAS:Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).Fórmula:C14H22N4O2Pureza:98%Cor e Forma:SolidPeso molecular:278.35Ziltivekimab
CAS:<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Pureza:95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:SoildIL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Fórmula:C33H41FN6O4Pureza:99.46%Cor e Forma:SolidPeso molecular:604.71
