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Receptor IL

Receptor IL

Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.

Foram encontrados 109 produtos de "Receptor IL"

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  • Nidanilimab

    CAS:
    <p>Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.</p>
    Pureza:> 95%
    Cor e Forma:Soild
    Peso molecular:150 kDa
  • Imsidolimab

    CAS:
    <p>Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.</p>
    Pureza:99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)
    Cor e Forma:Liquid
  • BRD6989

    CAS:
    BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.
    Fórmula:C16H16N4
    Pureza:99.43%
    Cor e Forma:Solid
    Peso molecular:264.33
  • YQ128

    CAS:
    YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.
    Fórmula:C27H29ClN2O4S2
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:545.11
  • Abrezekimab

    CAS:
    Abrezekimab (VR 942), a humanized antibody, blocks IL-13/IL-13Rα1, for asthma/lung disease study.
    Pureza:98.34% (SEC-HPLC) - 98.34% (SEC-HPLC)
    Cor e Forma:Liquid
    Peso molecular:48.1 kDa
  • Olokizumab

    CAS:
    Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.
    Pureza:99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)
    Cor e Forma:Liquid
  • Ixekizumab

    CAS:
    Ixekizumab: IgG4 antibody, neutralizes IL-17A (<3 pM), treats severe plaque psoriasis & arthritis.
    Pureza:98.86% (SEC-HPLC) - > 99.3% (SDS-PAGE); 95.4% (SEC-HPLC)
    Cor e Forma:Liquid
    Peso molecular:146.2 kDa
  • Briakinumab

    CAS:
    Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.
    Pureza:>95%
    Cor e Forma:Liquid
  • Elsilimomab

    CAS:
    Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.
    Pureza:>95%
    Cor e Forma:Liquid
  • Perakizumab

    CAS:
    <p>Perakizumab (RG4934) is a humanized monoclonal antibody targeting IL-17A, used in the study of psoriatic arthritis and other autoimmune diseases.</p>
    Pureza:95.28% (SEC-HPLC) - 99.66% (SEC-HPLC)
    Cor e Forma:Liquid
    Peso molecular:145.4 (kDa)
  • IL-15-IN-1

    CAS:
    IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
    Fórmula:C30H36N6O4S
    Pureza:99.16%
    Cor e Forma:Solid
    Peso molecular:576.71
  • Dupilumab

    CAS:
    Dupilumab (REGN-668) is a systemic immunomodulator for AD.
    Pureza:95.00% - >99.2%
    Cor e Forma:Liquid
  • Vobarilizumab

    CAS:
    Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.
    Pureza:>95%
    Cor e Forma:Liquid
  • Bermekimab

    CAS:
    Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.
    Cor e Forma:Liquid
    Peso molecular:145.45 kDa
  • Sarilumab

    CAS:
    Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.
    Pureza:97.4%
    Cor e Forma:Liquid
    Peso molecular:144.12 kDa
  • Xeligekimab

    CAS:
    Xeligekimab (GR 1501) is a fully humanized monoclonal antibody that neutralizes IL-17A and has anti-inflammatory activity for the study of plaque psoriasis.
    Pureza:95%
    Cor e Forma:Liquid
  • Siltuximab

    CAS:
    <p>Siltuximab(CNTO-328) is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.</p>
    Pureza:100% (SEC-HPLC) - > 95%
    Cor e Forma:Liquid
    Peso molecular:144.98 kDa
  • Vunakizumab

    CAS:
    <p>Vunakizumab is a humanized IgGκ monoclonal antibody targeting IL-17A, often linked to interleukin 22 to form Vunakizumab-IL22.</p>
    Pureza:95%
    Cor e Forma:Liquid
  • Olamkicept

    CAS:
    Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.
    Pureza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)
    Cor e Forma:Liquid
  • Risankizumab

    CAS:
    Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.
    Pureza:SDS-PAGE:95.3%;SEC-HPLC:98.3%
    Cor e Forma:Liquid
    Peso molecular:145.85 kDa
  • 2-Benzothiazolamine

    CAS:
    2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.
    Fórmula:C7H6N2S
    Pureza:99.09% - 99.3%
    Cor e Forma:Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)
    Peso molecular:150.2
  • Brodalumab

    CAS:
    <p>Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.</p>
    Pureza:98.3%
    Cor e Forma:Liquid
    Peso molecular:144.06 kDa
  • Enokizumab

    CAS:
    <p>Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.</p>
    Pureza:SDS-PAGE:95% SEC-HPLC:99.23%
    Cor e Forma:Liquid
    Peso molecular:145.98 kDa
  • PF-07038124 HCl

    CAS:
    PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.
    Fórmula:C18H23BClNO4
    Pureza:97.34% - 99.13%
    Cor e Forma:Soild
    Peso molecular:363.64
  • Ordesekimab

    CAS:
    Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.
    Pureza:> 95%
    Cor e Forma:Liquid
    Peso molecular:145.12 kDa
  • Tildrakizumab

    CAS:
    <p>Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.</p>
    Pureza:> 95%
    Cor e Forma:Liquid
    Peso molecular:144.44 kDa
  • Mirikizumab

    CAS:
    Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).
    Pureza:98.41% (SEC-HPLC) - 98.41% (SEC-HPLC)
    Cor e Forma:Liquid
  • Levilimab

    CAS:
    <p>Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.</p>
    Pureza:97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)
    Cor e Forma:Liquid
  • Spesolimab

    CAS:
    Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.
    Pureza:> 95%
    Cor e Forma:Liquid
    Peso molecular:150 kDa
  • MyD88-IN-1

    CAS:
    <p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>
    Fórmula:C23H24N6O7S
    Pureza:>99.99%
    Cor e Forma:Soild
    Peso molecular:528.54
  • Ziltivekimab

    CAS:
    <p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>
    Pureza:95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)
    Cor e Forma:Soild
  • Torudokimab


    <p>Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.</p>
    Pureza:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)
    Cor e Forma:Odour Liquid
  • Daclizumab

    CAS:
    <p>Daclizumab (Zenapax), a humanized antibody, blocks IL-2 by targeting CD25, used in multiple sclerosis.</p>
    Pureza:SDS-PAGE:95% SEC-HPLC:99.99%
    Cor e Forma:Liquid
    Peso molecular:144.12 kDa
  • Pascolizumab

    CAS:
    <p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>
    Pureza:> 95%
    Cor e Forma:Liquid
    Peso molecular:147.18 kDa
  • Nosantine racemate

    CAS:
    Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).
    Fórmula:C14H22N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:278.35
  • Mepolizumab

    CAS:
    Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.
    Pureza:98% - 98%
    Cor e Forma:Liquid
  • Guselkumab

    CAS:
    Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.
    Pureza:SDS-PAGE:95% SEC-HPLC:98.97%
    Cor e Forma:Liquid
    Peso molecular:144.8 kDa
  • Dectrekumab

    CAS:
    <p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>
    Pureza:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)
    Cor e Forma:Liquid
  • Canakinumab

    CAS:
    <p>Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout &amp; coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).</p>
    Pureza:98.8%
    Cor e Forma:Liquid
    Peso molecular:145.18 kDa
  • Anti-inflammatory agent 42

    CAS:
    Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.
    Fórmula:C20H12N2OS
    Pureza:99.47%
    Cor e Forma:Solid
    Peso molecular:328.39
  • Triphenyl phosphate

    CAS:
    Triphenyl phosphate is an flame retardant and endocrine disruptor that activates MAO-A/ROS/NF-κB pathways, disrupting placental tryptophan metabolism.
    Fórmula:C18H15O4P
    Pureza:99.94%
    Peso molecular:326.288
  • Temtokibart

    CAS:
    <p>Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.</p>
    Cor e Forma:Liquid
    Peso molecular:145.5
  • PF-06342674


    <p>PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.</p>
    Cor e Forma:Liquid
    Peso molecular:145.5kDa
  • Macrophage-activating lipopeptide 2 TFA


    Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist activates immune cell responses macrophages,
    Fórmula:C99H167N19O30S·xC2HF3O2
    Pureza:97.56%
    Cor e Forma:Solid
    Peso molecular:2135.56 (free base)
  • Reslizumab

    CAS:
    Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.
    Pureza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)
    Cor e Forma:Liquid
    Peso molecular:N/A
  • Stapokibart

    CAS:
    <p>Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα, blocking IL-4Rα-mediated signaling. It is used in studies of atopic dermatitis.</p>
    Pureza:96.09% (SEC-HPLC) - 96.09% (SEC-HPLC)
    Cor e Forma:Liquid
  • CNTO 607


    <p>CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.</p>
    Pureza:98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)
    Cor e Forma:Odour Liquid
  • Y13g dihydrochloride


    <p>Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are</p>
    Fórmula:C16H25ClN2O4
    Pureza:97.81%
    Cor e Forma:Soild
    Peso molecular:344.83
  • ABzOH

    CAS:
    <p>2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.</p>
    Fórmula:C12H10O2
    Pureza:99.43%
    Cor e Forma:Solid
    Peso molecular:186.21
  • Anakinra

    CAS:
    Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.
    Fórmula:C759H1186N208O232S10
    Pureza:95% - ≥95%
    Cor e Forma:Solid
    Peso molecular:17257.6
  • Anti-Mouse IL-4 Antibody (11B11)


    Anti-Mouse IL-4 Antibody (11B11) is an inhibitory antibody targeting mouse IL-4, with the clone number 11B11.
    Pureza:99%
    Cor e Forma:Odour Liquid
  • Anti-Human IL-17A

    CAS:
    <p>Anti-Human IL-17A (Secukinumab H chain) is a human monoclonal antibody targeting IL-17A, offering high affinity and low immunogenicity for psoriasis.</p>
    Pureza:98%
    Cor e Forma:Liquid
    Peso molecular:151 kDa
  • IL-17A antagonist 1

    CAS:
    IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.
    Fórmula:C33H41FN6O4
    Pureza:99.46%
    Cor e Forma:Solid
    Peso molecular:604.71
  • IL-17A inhibitor 1

    CAS:
    <p>IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of &lt;9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.</p>
    Fórmula:C24H27F5N8O4
    Pureza:99.37% - 99.37%
    Cor e Forma:Solid
    Peso molecular:586.51
  • Apilimod 2HCl

    CAS:
    Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.
    Fórmula:C23H28Cl2N6O2
    Pureza:98.41%
    Cor e Forma:Solid
    Peso molecular:491.41
  • CP 424174

    CAS:
    CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.
    Fórmula:C22H29ClN2O4S
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:452.99
  • GIBH-130

    CAS:
    GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
    Fórmula:C20H20N6O
    Pureza:99.52%
    Cor e Forma:Solid
    Peso molecular:360.41
  • VGX-1027

    CAS:
    VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.
    Fórmula:C11H11NO3
    Pureza:99.54% - 99.86%
    Cor e Forma:Solid
    Peso molecular:205.21
  • Apilimod

    CAS:
    <p>Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.</p>
    Fórmula:C23H26N6O2
    Pureza:99.38% - 99.89%
    Cor e Forma:Solid
    Peso molecular:418.49
  • Esonarimod

    CAS:
    Esonarimod (KE-298) is an antirheumatic drug.
    Fórmula:C14H16O4S
    Pureza:97.44%
    Cor e Forma:Solid
    Peso molecular:280.34
  • Secukinumab

    CAS:
    Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for the
    Pureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%
    Cor e Forma:Liquid
    Peso molecular:147.93 kDa
  • RO2959 Hydrochloride

    CAS:
    RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
    Fórmula:C21H20ClF2N5OS
    Pureza:99.24%
    Cor e Forma:Solid
    Peso molecular:463.93
  • Apilimod mesylate

    CAS:
    Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.
    Fórmula:C25H34N6O8S2
    Pureza:99.51% - ≥95%
    Cor e Forma:Solid
    Peso molecular:610.7
  • GSK717

    CAS:
    <p>GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.</p>
    Fórmula:C28H28N4O2
    Pureza:97.34% - 99.01%
    Cor e Forma:Solid
    Peso molecular:452.55
  • Ossirene

    CAS:
    Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
    Fórmula:C2H4Cl3O2Te·H4N
    Pureza:≥98%
    Cor e Forma:Solid
    Peso molecular:312.05
  • YM-90709

    CAS:
    YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.
    Fórmula:C22H21N3O2
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:359.42
  • Suplatast (Tosilate)

    CAS:
    Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
    Fórmula:C23H33NO7S2
    Pureza:99.34% - 99.65%
    Cor e Forma:White Or Off-White Crystals
    Peso molecular:499.64
  • Clodronate disodium tetrahydrate

    CAS:
    <p>Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.</p>
    Fórmula:CH10Cl2Na2O10P2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:360.92
  • Satralizumab

    CAS:
    Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).
    Pureza:95%
    Cor e Forma:Liquid
  • Brazikumab

    CAS:
    Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.
    Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)
    Cor e Forma:Liquid
  • Sirukumab

    CAS:
    <p>Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.</p>
    Pureza:>95%
    Cor e Forma:Liquid
    Peso molecular:144.6 (kDa)
  • Picankibart

    CAS:
    Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.
    Pureza:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)
    Cor e Forma:Liquid
  • Bempikibart

    CAS:
    Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.
    Pureza:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)
    Cor e Forma:Liquid
  • Anti-Mouse IL-6R Antibody (15A7)


    Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experiments
    Pureza:99% - 99%
    Cor e Forma:Odour Liquid
  • Lebrikizumab

    CAS:
    Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.
    Pureza:95%
    Cor e Forma:Liquid
  • Anrukinzumab

    CAS:
    <p>Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.</p>
    Pureza:95%
    Cor e Forma:Liquid
  • Afasevikumab

    CAS:
    Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.
    Pureza:95%
    Cor e Forma:Liquid
  • Gevokizumab

    CAS:
    Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.
    Pureza:95%
    Cor e Forma:Liquid
  • Ebdarokimab

    CAS:
    Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.
    Pureza:95%
    Cor e Forma:Liquid
  • Ziralimumab

    CAS:
    Ziralimumab(ABX-RB2) is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.
    Pureza:95%
    Cor e Forma:Liquid
  • Rademikibart

    CAS:
    Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without
    Pureza:95%
    Cor e Forma:Liquid
  • Gumokimab

    CAS:
    Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.
    Pureza:95%
    Cor e Forma:Liquid
  • Bimekizumab

    CAS:
    <p>Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.</p>
    Pureza:>99.99%
    Cor e Forma:Liquid
  • Inolimomab

    CAS:
    Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).
    Pureza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)
    Cor e Forma:Liquid
  • Manfidokimab

    CAS:
    <p>Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.</p>
    Pureza:95%
    Cor e Forma:Liquid
  • Casdozokitug

    CAS:
    Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.
    Pureza:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)
    Cor e Forma:Liquid
  • Tirnovetmab

    CAS:
    Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.
    Pureza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)
    Cor e Forma:Liquid
  • Lusvertikimab

    CAS:
    <p>Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.</p>
    Pureza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)
    Cor e Forma:Liquid
  • D228

    CAS:
    <p>D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).</p>
    Fórmula:C22H28O12
    Pureza:99.91%
    Cor e Forma:Solid
    Peso molecular:484.45
  • Vopikitug

    CAS:
    <p>Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.</p>
    Pureza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)
    Cor e Forma:Liquid
  • Etokimab

    CAS:
    <p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>
    Pureza:95%
    Cor e Forma:Liquid
  • A-802715

    CAS:
    <p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>
    Fórmula:C16H26N4O3
    Pureza:96.29%
    Cor e Forma:Solid
    Peso molecular:322.4
  • BI605906

    CAS:
    <p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>
    Fórmula:C17H22F2N4O3S2
    Pureza:97.14%
    Cor e Forma:Solid
    Peso molecular:432.51
  • IL-4-inhibitor-1

    CAS:
    <p>IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).</p>
    Fórmula:C18H12FN3O2
    Pureza:98.78% - 99.53%
    Cor e Forma:Solid
    Peso molecular:321.31
  • BIRT-377

    CAS:
    BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).
    Fórmula:C18H15BrCl2N2O2
    Pureza:99.93%
    Cor e Forma:Solid
    Peso molecular:442.13
  • Dersalazine

    CAS:
    <p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>
    Fórmula:C35H32N6O4
    Pureza:99.62%
    Cor e Forma:Solid
    Peso molecular:600.67
  • NO-prednisolone

    CAS:
    NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.
    Fórmula:C29H33NO9
    Pureza:98.65%
    Cor e Forma:Solid
    Peso molecular:539.57
  • NFAT Transcription Factor Regulator-1

    CAS:
    NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).
    Fórmula:C17H10F6N4O2
    Pureza:99.90%
    Cor e Forma:Solid
    Peso molecular:416.28
  • Resiniferatoxin

    CAS:
    <p>Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.</p>
    Fórmula:C37H40O9
    Pureza:93.08% - 99.34%
    Cor e Forma:Solid
    Peso molecular:628.71
  • LMT-28

    CAS:
    <p>LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.</p>
    Fórmula:C17H29NO4
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:311.42