Receptor IL
Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.
Foram encontrados 110 produtos de "Receptor IL"
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Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePureza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Cor e Forma:LiquidPeso molecular:147.93 kDaSuplatast (Tosilate)
CAS:Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.Fórmula:C23H33NO7S2Pureza:99.34% - 99.65%Cor e Forma:White Or Off-White CrystalsPeso molecular:499.64RO2959 Hydrochloride
CAS:RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.Fórmula:C21H20ClF2N5OSPureza:99.24%Cor e Forma:SolidPeso molecular:463.93GSK717
CAS:<p>GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.</p>Fórmula:C28H28N4O2Pureza:97.34% - 99.01%Cor e Forma:SolidPeso molecular:452.55Apilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Fórmula:C25H34N6O8S2Pureza:99.51% - ≥95%Cor e Forma:SolidPeso molecular:610.7CP 424174
CAS:CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.Fórmula:C22H29ClN2O4SPureza:>99.99%Cor e Forma:SolidPeso molecular:452.99YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Fórmula:C22H21N3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:359.42Clodronate disodium tetrahydrate
CAS:<p>Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.</p>Fórmula:CH10Cl2Na2O10P2Pureza:98%Cor e Forma:SolidPeso molecular:360.92Sirukumab
CAS:<p>Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.</p>Pureza:>95%Cor e Forma:LiquidPeso molecular:144.6 (kDa)Satralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Pureza:95%Cor e Forma:LiquidBrazikumab
CAS:Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.Pureza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:LiquidPicankibart
CAS:Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.Pureza:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidBempikibart
CAS:Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.Pureza:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)Cor e Forma:LiquidAnti-Mouse IL-6R Antibody (15A7)
Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experimentsPureza:99% - 99%Cor e Forma:Odour LiquidSapelizumab
Sapelizumab is a humanised antibody targeting IL-6Ra/CD126, huIgG2-type heavy chains and huκ-type light chains, IL-6 antagonist NMOSD.Lebrikizumab
CAS:Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.Pureza:95%Cor e Forma:LiquidAnrukinzumab
CAS:<p>Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.</p>Pureza:95%Cor e Forma:LiquidAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Pureza:95%Cor e Forma:LiquidGevokizumab
CAS:Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.Pureza:95%Cor e Forma:LiquidEbdarokimab
CAS:Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.Pureza:95%Cor e Forma:Liquid
