Receptor IL
Os receptores de interleucina (receptores IL) são um grupo de receptores que se ligam às interleucinas, uma família de citocinas que desempenham papéis essenciais na regulação do sistema imunológico, inflamação e hematopoiese. A desregulação da sinalização de interleucina está associada a várias doenças inflamatórias e autoimunes, tornando os receptores IL alvos críticos para a intervenção terapêutica. Antagonistas dos receptores IL estão sendo explorados para o tratamento de condições como artrite reumatoide, psoríase e doenças inflamatórias intestinais. Na CymitQuimica, oferecemos uma gama de moduladores de receptores IL de alta qualidade para apoiar sua pesquisa em sinalização de citocinas, imunologia e terapia de doenças inflamatórias.
Foram encontrados 110 produtos de "Receptor IL"
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Ziralimumab
CAS:Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.Pureza:95%Cor e Forma:LiquidRademikibart
CAS:Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, withoutPureza:95%Cor e Forma:LiquidGumokimab
CAS:Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.Pureza:95%Cor e Forma:LiquidBimekizumab
CAS:Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.Pureza:>99.99%Cor e Forma:LiquidInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Pureza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Cor e Forma:LiquidManfidokimab
CAS:Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.Pureza:95%Cor e Forma:LiquidCasdozokitug
CAS:Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.Pureza:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)Cor e Forma:LiquidTirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Pureza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Cor e Forma:LiquidLusvertikimab
CAS:Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.Pureza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:LiquidD228
CAS:<p>D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).</p>Fórmula:C22H28O12Pureza:99.91%Cor e Forma:SolidPeso molecular:484.45Vopikitug
CAS:Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.Pureza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Cor e Forma:LiquidEtokimab
CAS:<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Pureza:95%Cor e Forma:LiquidA-802715
CAS:<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Fórmula:C16H26N4O3Pureza:96.29%Cor e Forma:SolidPeso molecular:322.4BI605906
CAS:<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Fórmula:C17H22F2N4O3S2Pureza:97.14%Cor e Forma:SolidPeso molecular:432.51IL-4-inhibitor-1
CAS:IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).Fórmula:C18H12FN3O2Pureza:99.53% - 99.89%Cor e Forma:SolidPeso molecular:321.31BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Fórmula:C18H15BrCl2N2O2Pureza:99.93%Cor e Forma:SolidPeso molecular:442.13Dersalazine
CAS:<p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>Fórmula:C35H32N6O4Pureza:99.62%Cor e Forma:SolidPeso molecular:600.67NO-prednisolone
CAS:NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.Fórmula:C29H33NO9Pureza:98.65%Cor e Forma:SolidPeso molecular:539.57NFAT Transcription Factor Regulator-1
CAS:NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).Fórmula:C17H10F6N4O2Pureza:99.90%Cor e Forma:SolidPeso molecular:416.28Resiniferatoxin
CAS:Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.Fórmula:C37H40O9Pureza:93.08% - 99.34%Cor e Forma:SolidPeso molecular:628.71
