MAPK
As MAPKs são uma família de proteínas quinases envolvidas em uma variedade de processos celulares, incluindo crescimento, proliferação, diferenciação e respostas ao estresse. A via de sinalização MAPK consiste em várias camadas, incluindo ERK, JNK e p38 MAPKs, cada uma desempenhando papéis distintos na função celular. A desregulação da sinalização MAPK está ligada ao câncer, doenças inflamatórias e distúrbios metabólicos. Na CymitQuimica, oferecemos uma ampla gama de inibidores e ativadores de MAPK para apoiar sua pesquisa em biologia celular, transdução de sinais e mecanismos de doenças.
Foram encontrados 890 produtos de "MAPK"
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HPK1-IN-4
CAS:HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.Fórmula:C23H26N6O3Pureza:97.06%Cor e Forma:SolidPeso molecular:434.49Ref: TM-T40350
1mg123,00€5mg295,00€10mg447,00€25mg782,00€50mg1.071,00€100mg1.468,00€1mL*10mM (DMSO)326,00€TAK1-IN-3
CAS:TAK1-IN-3 is a novel ATP-competitive TAK1 inhibitor for the study of cancer.Fórmula:C16H19N3O2SPureza:98.88%Cor e Forma:SolidPeso molecular:317.41S6K1-IN-DG2
CAS:S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.Fórmula:C16H17BrN6OPureza:99.99%Cor e Forma:SolidPeso molecular:389.25Enniatin B1
CAS:Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier and modulates ERK, NF-κB, and ACAT with an IC50 of 73 μM.Fórmula:C34H59N3O9Pureza:98%Cor e Forma:SolidPeso molecular:653.858LC-2
CAS:LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is aFórmula:C59H71ClFN11O7SPureza:98%Cor e Forma:SolidPeso molecular:1132.78RAS GTPase inhibitor 1
CAS:RAS GTPase inhibitor 1 is a RAS GTPase inhibitor with potential antitumor activity.Fórmula:C27H28ClF4N5O2Pureza:98.43%Cor e Forma:SolidPeso molecular:565.99Anti-ERK2 Antibody (5V598)
Anti-ERK2 Antibody (5V598) is a Rabbit antibody targeting ERK2. Anti-ERK2 Antibody (5V598) can be used in ELISA.Cor e Forma:Odour LiquidAnti-ERK2 Antibody (4F551)
Anti-ERK2 Antibody (4F551) is a Rabbit antibody targeting ERK2. Anti-ERK2 Antibody (4F551) can be used in ELISA,FCM.Cor e Forma:Odour LiquidAnti-ERK2 Antibody (9C922)
Anti-ERK2 Antibody (9C922) is a Mouse antibody targeting ERK2. Anti-ERK2 Antibody (9C922) can be used in WB,ELISA.Cor e Forma:Odour LiquidTunlametinib
CAS:Tunlametinib is a MEK1/2 inhibitor (IC50=1.9 nM) for treating RAS/RAF-driven cancers.Fórmula:C16H12F2IN3O3SPureza:98.72%Cor e Forma:SolidPeso molecular:491.25Enniatin B
CAS:Enniatins B decreases the activation of ERK (p44/p42).Fórmula:C33H57N3O9Pureza:98%Cor e Forma:SolidPeso molecular:639.831CE3F4 analog 1
CAS:CE3F4 analog 1 is an analogue of CE3F4.Fórmula:C11H9Br3FNOCor e Forma:SolidPeso molecular:429.909TRPM4 inhibitor 8
CAS:TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.Fórmula:C11H17BrN2Pureza:99.84%Cor e Forma:SolidPeso molecular:257.17Ref: TM-T9776
5mg44,00€10mg62,00€25mg90,00€50mg170,00€100mg268,00€200mg403,00€500mg660,00€1mL*10mM (DMSO)48,00€Cephradine (Standard)
CAS:Cephradine (Standard) is the standard substance of Cephradine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.Fórmula:C16H19N3O4SPeso molecular:349.40PD0325901-O-C2-dioxolane
CAS:The main body of PD0325901-O-C2-dioxolane is PD0325901, a non-ATP-competitive MEK1/2 inhibitor, with anticancer effects of decreasing ERK phosphorylation.Fórmula:C18H16F3IN2O4Cor e Forma:SolidPeso molecular:508.23JH295
CAS:JH295: potent, selective Nek2 inhibitor (IC50 = 770 nM), irreversibly targets Cys22, no effect on Cdk1, Aurora B, Plk1, or spindle mechanisms.Fórmula:C18H16N4O2Cor e Forma:SolidPeso molecular:320.352MLK-IN-1
CAS:MLK-IN-1 is a potent and selective mixed-lineage kinase 3 (MLK-3) inhibitor, showing excellent brain penetration and high specificity for MLK-3. MLK-IN-1 at 100 nM supports sustained axonogenesis in cultures challenged with HIV-1 Tat-activated microglia and protects neuronal cells from Tat-induced damage, establishing it as a valuable probe for neuroinflammation and neurodegeneration research.Fórmula:C23H20N4O3SPureza:99.74%Cor e Forma:SolidPeso molecular:432.5Ref: TM-T39102
1mg54,00€5mg114,00€10mg178,00€25mg394,00€50mg620,00€100mg982,00€1mL*10mM (DMSO)126,00€Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Fórmula:C15H12O5Pureza:98.76% - >99.99%Cor e Forma:SolidPeso molecular:272.25Ref: TM-T6427
1mg40,00€2mg52,00€5mg84,00€10mg101,00€25mg202,00€50mg326,00€100mg520,00€1mL*10mM (DMSO)82,00€L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Fórmula:C20H14ClN3OPureza:≥95%Cor e Forma:SolidPeso molecular:347.8CC-90001
CAS:CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.Fórmula:C16H27N5O2Pureza:99.96%Cor e Forma:SolidPeso molecular:321.42
