Ras
As proteínas Ras são pequenas GTPases que atuam como interruptores moleculares na via de sinalização MAPK, controlando o crescimento, a diferenciação e a sobrevivência celular. Ras ativado inicia uma cascata de sinalização que inclui Raf, MEK e ERK, levando a várias respostas celulares. As mutações nos genes Ras são comuns em cânceres, tornando Ras um foco importante da pesquisa sobre o câncer. Na CymitQuimica, oferecemos uma variedade de moduladores de Ras para apoiar sua pesquisa em biologia do câncer, transdução de sinais e desenvolvimento terapêutico.
Foram encontrados 155 produtos de "Ras"
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ESI-08
CAS:<p>ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.</p>Fórmula:C20H23N3OSPureza:97.17%Cor e Forma:SolidPeso molecular:353.48KRAS inhibitor-6
CAS:<p>KRAS inhibitor-6 is a potent KRAS G12C inhibitor.</p>Fórmula:C27H30ClF2N5O3Pureza:98%Cor e Forma:SolidPeso molecular:546.01Methylophiopogonanone B
CAS:<p>1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.</p>Fórmula:C19H20O5Pureza:99.24% - 99.83%Cor e Forma:SolidPeso molecular:328.36MCP110
CAS:<p>MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.</p>Fórmula:C33H36N2O3Pureza:97.23%Cor e Forma:OilPeso molecular:508.65BI-2852
CAS:<p>BI-2852: nanomolar affinity KRAS switch I/II pocket inhibitor; blocks signaling, halts KRAS mutant cell growth.</p>Fórmula:C31H28N6O2Pureza:98.98%Cor e Forma:SolidPeso molecular:516.59PROTAC KRAS G12C degrader-3
CAS:<p>PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].</p>Fórmula:C63H75ClN14O6Pureza:98%Cor e Forma:SolidPeso molecular:1159.81KRAS G12C inhibitor 58
CAS:<p>KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].</p>Fórmula:C51H64ClF4N9O8SPureza:98%Cor e Forma:SolidPeso molecular:1074.62KRAS G12C inhibitor 5
CAS:<p>KRAS G12C inhibitor 5 is a KRas G12C inhibitor.</p>Fórmula:C32H37N7O2Pureza:98%Cor e Forma:SolidPeso molecular:551.68KRAS G12D modulator-1
CAS:<p>KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and is</p>Fórmula:C30H36FN5O4Pureza:98%Cor e Forma:SolidPeso molecular:549.64Rac1-IN-3
CAS:<p>Rac1-IN-3 (Compound 2) is a Rac1 inhibitor exhibiting an inhibitory concentration 50 (IC50) of 46.1 μM [1].</p>Fórmula:C21H23N7O2Pureza:98%Cor e Forma:SolidPeso molecular:405.45TH-Z827
CAS:<p>TH-Z827 is a mutant-selective inhibitor targeting KRAS(G12D) with an IC50 of 2.4 μM, demonstrating specificity by not binding to KRAS(WT) or KRAS(G12C).</p>Fórmula:C30H38N6OPureza:98%Cor e Forma:SolidPeso molecular:498.66KRAS G12C inhibitor 32
CAS:<p>KRAS G12C Inhibitor 32, an eight-membered heterocyclic compound with nitrogen, acts as a potent inhibitor of KRAS G12C [1].</p>Fórmula:C29H30Cl3FN6O3Pureza:98%Cor e Forma:SolidPeso molecular:635.94SOS1/KRAS-IN-1
CAS:<p>SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1].</p>Fórmula:C24H26F3N5OPureza:98%Cor e Forma:SolidPeso molecular:457.49pan-KRAS-IN-2
CAS:<p>Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12D</p>Fórmula:C34H34F2N4O3Pureza:98%Cor e Forma:SolidPeso molecular:584.66pan-KRAS-IN-3
CAS:<p>Pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor suitable for cancer research [1].</p>Fórmula:C33H32F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:587.63KRas G12C inhibitor 1
CAS:<p>KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.</p>Fórmula:C31H38N6O3Pureza:98%Cor e Forma:SolidPeso molecular:542.67XRP44X
CAS:<p>XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.</p>Fórmula:C21H21ClN4OPureza:99.67%Cor e Forma:SolidPeso molecular:380.87KRAS G12C inhibitor 59
CAS:<p>KRAS G12C Inhibitor 59 is a compound with anticancer properties.</p>Fórmula:C32H39F6N7O5Pureza:98%Cor e Forma:SolidPeso molecular:715.69RBC10
CAS:<p>RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-</p>Fórmula:C24H25ClN2O2Pureza:99.71%Cor e Forma:SolidPeso molecular:408.92KRAS G12C inhibitor 14
CAS:<p>KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].</p>Fórmula:C24H19ClF2N4O3Pureza:98%Cor e Forma:SolidPeso molecular:484.88
