Canal de Potássio
Os canais de potássio são um grupo diversificado de proteínas de membrana que facilitam o fluxo de íons de potássio (K+) através da membrana celular. Esses canais desempenham um papel crucial na manutenção do potencial de membrana em repouso, na regulação do volume celular e no controle da excitabilidade de neurônios e células musculares. Os canais de potássio estão envolvidos em vários processos fisiológicos, incluindo a regulação do ritmo cardíaco, a secreção de insulina e a liberação de neurotransmissores. A desregulação dos canais de potássio está associada a condições como arritmias, epilepsia e hipertensão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de canais de potássio para apoiar sua pesquisa em eletrofisiologia, saúde cardiovascular e neurobiologia.
Foram encontrados 280 produtos de "Canal de Potássio"
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Oxybutynin
CAS:Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.Fórmula:C22H31NO3Pureza:97.81% - 99.57%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:357.49Clofilium tosylate
CAS:<p>Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.</p>Fórmula:C28H44ClNO3SPureza:99.68%Cor e Forma:SolidPeso molecular:510.174-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Fórmula:C5H6N2Pureza:91.61%Cor e Forma:SolidPeso molecular:94.11Glipizide
CAS:Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.Fórmula:C21H27N5O4SPureza:99.67% - 99.75%Cor e Forma:SolidPeso molecular:445.54NS13001
CAS:<p>NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).</p>Fórmula:C17H16ClN7Pureza:99.55%Cor e Forma:SolidPeso molecular:353.81Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Fórmula:C17H17ClF6N2OPureza:99% - 99.99%Cor e Forma:Off-White To Yellow SolidPeso molecular:414.77Dronedarone hydrochloride
CAS:Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Fórmula:C31H44N2O5S·HClPureza:99.61%Cor e Forma:SolidPeso molecular:593.22VU591 hydrochloride
CAS:VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.Fórmula:C16H13ClN6O5Pureza:98.93% - 99.22%Cor e Forma:SolidPeso molecular:404.76IK1 inhibitor PA-6
CAS:IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFórmula:C31H32N4O2Pureza:98.9%Cor e Forma:SolidPeso molecular:492.61Astemizole
CAS:Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.Fórmula:C28H31FN4OPureza:98.24% - 99.67%Cor e Forma:White Crystals SolidPeso molecular:458.57Eleclazine hydrochloride
CAS:Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Fórmula:C21H17ClF3N3O3Pureza:99.86%Cor e Forma:SolidPeso molecular:451.83Hydroxyhexamide
CAS:Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.Fórmula:C15H22N2O4SPureza:98.91%Cor e Forma:SolidPeso molecular:326.41Ropivacaine
CAS:Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Fórmula:C17H26N2OPureza:97.75% - >99.99%Cor e Forma:SolidPeso molecular:274.40ML418
CAS:ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Fórmula:C19H24ClN3O3Pureza:99.3%Cor e Forma:SolidPeso molecular:377.87BMS-394136
CAS:BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.Fórmula:C24H21Cl2FN4OPureza:98.59% - 99.95%Cor e Forma:SolidPeso molecular:471.35VU0134992 hydrochloride
CAS:VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).Fórmula:C20H32BrClN2O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:447.84Tannic acid
CAS:Tannic acid (Gallotannic acid) is a novel hERG channel blocker.Fórmula:C76H52O46Pureza:AR - ARCor e Forma:Light Yellow To Light Brown Solid Solid Particulate/PowderPeso molecular:1701.2Repaglinide
CAS:Repaglinide, a benzoic acid derivative, stimulates insulin, treats type 2 diabetes, and may rarely cause acute liver injury.Fórmula:C27H36N2O4Pureza:99.73% - >99.99%Cor e Forma:White To Off-White SolidPeso molecular:452.59Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Cor e Forma:SolidPeso molecular:494.00NS3623
CAS:NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Fórmula:C15H10BrF3N6OPureza:97.06%Cor e Forma:SolidPeso molecular:427.18
