Canal de Potássio
Os canais de potássio são um grupo diversificado de proteínas de membrana que facilitam o fluxo de íons de potássio (K+) através da membrana celular. Esses canais desempenham um papel crucial na manutenção do potencial de membrana em repouso, na regulação do volume celular e no controle da excitabilidade de neurônios e células musculares. Os canais de potássio estão envolvidos em vários processos fisiológicos, incluindo a regulação do ritmo cardíaco, a secreção de insulina e a liberação de neurotransmissores. A desregulação dos canais de potássio está associada a condições como arritmias, epilepsia e hipertensão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de canais de potássio para apoiar sua pesquisa em eletrofisiologia, saúde cardiovascular e neurobiologia.
Foram encontrados 323 produtos para "Canal de Potássio".
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Linoleoyl glycine
CAS:Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.Fórmula:C20H35NO3Pureza:97.04%Cor e Forma:White SolidPeso molecular:337.5VU0134992 hydrochloride
CAS:VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).Fórmula:C20H32BrClN2O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:447.84Linopirdine
CAS:Linopirdine (DuP 996) is a TRPV1 agonist.Fórmula:C26H21N3OPureza:99.45% - 99.78%Cor e Forma:SolidPeso molecular:391.46Ref: TM-T15758
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg119,00€25mg215,00€50mg371,00€100mg532,00€200mg767,00€500mg1.144,00€Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Fórmula:C21H29N3OPureza:99.62%Cor e Forma:White SolidPeso molecular:339.47Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Cor e Forma:White SolidPeso molecular:494Gliclazide
CAS:Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of theFórmula:C15H21N3O3SPureza:99.58% - 99.63%Cor e Forma:White SolidPeso molecular:323.41Doxapram hydrochloride hydrate
CAS:Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.Fórmula:C24H33ClN2O3C24H30N2O2·ClH·H2OPureza:99.64% - >99.99%Cor e Forma:SolidPeso molecular:432.99NS8593 hydrochloride
CAS:NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .Fórmula:C17H18ClN3Pureza:99.77%Cor e Forma:SolidPeso molecular:299.8Ref: TM-T12256
1mg43,00€2mg56,00€5mg88,00€1mL*10mM (DMSO)92,00€10mg150,00€25mg333,00€50mg497,00€100mg717,00€DCPIB
CAS:DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFórmula:C22H28Cl2O4Pureza:99.77% - 99.79%Cor e Forma:SolidPeso molecular:427.36Ref: TM-T10979
2mg39,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg87,00€25mg177,00€50mg301,00€100mg485,00€200mg690,00€VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuitFórmula:C20H22ClFN4O2SPureza:98.1%Cor e Forma:SolidPeso molecular:436.93Tipepidine hydrochloride
CAS:Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.Fórmula:C15H18ClNS2Pureza:99.97%Cor e Forma:White SolidPeso molecular:311.89Tannic acid
CAS:Tannic acid (Gallotannic acid) is a novel hERG channel blocker.Fórmula:C76H52O46Pureza:AR - ARCor e Forma:SolidPeso molecular:1701.206Oxybutynin chloride
CAS:Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties.Fórmula:C22H32ClNO3Pureza:99.27% - >99.99%Cor e Forma:White SolidPeso molecular:393.96BMS-394136
CAS:BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.Fórmula:C24H21Cl2FN4OPureza:98.59% - 99.95%Cor e Forma:White SolidPeso molecular:471.354-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Fórmula:C5H6N2Pureza:91.61%Cor e Forma:SolidPeso molecular:94.11Glipizide
CAS:Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.Fórmula:C21H27N5O4SPureza:99.67% - 99.75%Cor e Forma:SolidPeso molecular:445.54Ropivacaine hydrochloride
CAS:Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activityFórmula:C17H26N2O·HClPureza:99.85% - 99.95%Cor e Forma:SolidPeso molecular:310.86Indapamide
CAS:Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Fórmula:C16H16ClN3O3SPureza:98.97% - 99.83%Cor e Forma:SolidPeso molecular:365.83NS13001
CAS:NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Fórmula:C17H16ClN7Pureza:99.55%Cor e Forma:White SolidPeso molecular:353.81NS19504
CAS:NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM.Fórmula:C10H9BrN2SPureza:99.87%Cor e Forma:White SolidPeso molecular:269.16Ref: TM-T12255
5mg50,00€1mL*10mM (DMSO)52,00€10mg84,00€25mg166,00€50mg280,00€100mg420,00€500mg888,00€
