Canal de cloreto
Os canais de cloreto são proteínas de membrana que controlam o movimento dos íons cloreto através das membranas celulares, desempenhando um papel vital na manutenção do volume celular, excitabilidade elétrica e equilíbrio ácido-base. A desregulação dos canais de cloreto está associada a doenças como fibrose cística, epilepsia e distúrbios renais. Na CymitQuimica, oferecemos uma variedade de moduladores de canais de cloreto para apoiar sua pesquisa em transporte de íons, homeostase celular e mecanismos de doenças.
Foram encontrados 53 produtos para "Canal de cloreto".
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Adjudin
CAS:Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.Fórmula:C15H12Cl2N4OPureza:96.51% - ≥95%Cor e Forma:SolidPeso molecular:335.19Selamectin
CAS:Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening inFórmula:C43H63NO11Pureza:99.84%Cor e Forma:Yellow SolidPeso molecular:769.96Irisolidone
CAS:Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.Fórmula:C17H14O6Pureza:99.41% - 99.87%Cor e Forma:SolidPeso molecular:314.29Ref: TM-TN1035
1mg105,00€5mg250,00€1mL*10mM (DMSO)255,00€10mg378,00€25mg618,00€50mg859,00€100mg1.153,00€Fenamic acid
CAS:Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats.Fórmula:C13H11NO2Pureza:99.6%Cor e Forma:SolidPeso molecular:213.2319Anthracene-9-carboxylic acid
CAS:Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.Fórmula:C15H10O2Pureza:99.05%Cor e Forma:SolidPeso molecular:222.24Phenyl benzoate
CAS:Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid.It is an important organic synthesis intermediate.Fórmula:C13H10O2Pureza:99.63%Cor e Forma:White SolidPeso molecular:198.22Talniflumate
CAS:Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cellFórmula:C21H13F3N2O4Pureza:98% - 99.81%Cor e Forma:Yellow SolidPeso molecular:414.33NPPB
CAS:NPPB is a chloride channel blocker with IC50 of 80 nM .Fórmula:C16H16N2O4Pureza:99.95%Cor e Forma:White SolidPeso molecular:300.31MONNA
CAS:MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.Fórmula:C18H14N2O5Pureza:98.29%Cor e Forma:SolidPeso molecular:338.31CaCCinh-A01
CAS:CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).Fórmula:C18H21NO4SPureza:99.36% - >99.99%Cor e Forma:White SolidPeso molecular:347.43Org 25543
CAS:Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.Fórmula:C24H32N2O4Pureza:99.31%Cor e Forma:SolidPeso molecular:412.52Ref: TM-T50082
1mg55,00€5mg114,00€1mL*10mM (DMSO)129,00€10mg170,00€25mg274,00€50mg371,00€100mg522,00€200mg687,00€Guanidinoethyl sulfonate
CAS:Guanidinoethyl sulfonate (Taurocyamine) is a competitive glycine receptor antagonist.Fórmula:C3H9N3O3SPureza:99.43% - 99.47%Cor e Forma:White SolidPeso molecular:167.19H100
CAS:H100 inhibits Cl- transport, mildly affects NaK2Cl cotransporter and Band 3 anion exchanger, not KCl cotransporter.Fórmula:C18H16N2O6SPureza:98%Cor e Forma:SolidPeso molecular:388.4Bts 39542
CAS:Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.Fórmula:C16H11ClN4O3SCor e Forma:SolidPeso molecular:374.8BTG-1640
CAS:BTG-1640 is used potentially for the treatment of anxiety and panic disorder.Fórmula:C15H19NO2Cor e Forma:SolidPeso molecular:245.32NS-3736
CAS:NS-3736 is a chloride channel inhibitor that has been shown to prevent osteoclastic acidification and resorption.Fórmula:C15H9BrClF3N6OCor e Forma:SolidPeso molecular:461.62ANO1-IN-2
CAS:ANO1-IN-2: potent ANO1 blocker (IC50: 1.75 μM), less effective on ANO2 (IC50: 7.43 μM), inhibits glioblastoma cell growth.Fórmula:C16H14ClN3O2S2Cor e Forma:SolidPeso molecular:379.88IAA-94
CAS:IAA-94 is an inhibitor of chloride channels, it binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM.Fórmula:C17H18Cl2O4Cor e Forma:SolidPeso molecular:357.23Alilusem
CAS:Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.Fórmula:C17H15ClKN2O5SCor e Forma:SolidPeso molecular:433.92
