Canal de cloreto
Os canais de cloreto são proteínas de membrana que controlam o movimento dos íons cloreto através das membranas celulares, desempenhando um papel vital na manutenção do volume celular, excitabilidade elétrica e equilíbrio ácido-base. A desregulação dos canais de cloreto está associada a doenças como fibrose cística, epilepsia e distúrbios renais. Na CymitQuimica, oferecemos uma variedade de moduladores de canais de cloreto para apoiar sua pesquisa em transporte de íons, homeostase celular e mecanismos de doenças.
Foram encontrados 54 produtos de "Canal de cloreto"
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Phenyl benzoate
CAS:Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid.It is an important organic synthesis intermediate.Fórmula:C13H10O2Pureza:99.63%Cor e Forma:White Crystalline PowderPeso molecular:198.22Irisolidone
CAS:Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
Fórmula:C17H14O6Pureza:99.41% - 99.87%Cor e Forma:SolidPeso molecular:314.29Anthracene-9-carboxylic acid
CAS:Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.Fórmula:C15H10O2Pureza:99.05%Cor e Forma:Yellow Cystalline PowderPeso molecular:222.24Selamectin
CAS:Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening inFórmula:C43H63NO11Pureza:99.84%Cor e Forma:SolidPeso molecular:769.96MONNA
CAS:MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.Fórmula:C18H14N2O5Pureza:98.29%Cor e Forma:SolidPeso molecular:338.31Lubiprostone
CAS:Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.Fórmula:C20H32F2O5Pureza:97.31% - 98.54%Cor e Forma:White Odorless Crystals Or Crystalline PowderPeso molecular:390.46Talniflumate
CAS:Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell
Fórmula:C21H13F3N2O4Pureza:98% - 99.81%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:414.33NPPB
CAS:NPPB is a chloride channel blocker with IC50 of 80 nM .Fórmula:C16H16N2O4Pureza:99.95%Cor e Forma:Light Yellow To Yellow SolidPeso molecular:300.31Guanidinoethyl sulfonate
CAS:Guanidinoethyl sulfonate (Taurocyamine) is a competitive glycine receptor antagonist.Fórmula:C3H9N3O3SPureza:99.43% - 99.47%Cor e Forma:SolidPeso molecular:167.19Org 25543
CAS:Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.Fórmula:C24H32N2O4Pureza:99.13%Cor e Forma:SolidPeso molecular:412.52Ref: TM-T50082
1mg55,00€5mg114,00€1mL*10mM (DMSO)129,00€10mg170,00€25mg274,00€50mg371,00€100mg522,00€200mg687,00€CaCCinh-A01
CAS:CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).Fórmula:C18H21NO4SPureza:99.36% - >99.99%Cor e Forma:SolidPeso molecular:347.43Adjudin
CAS:Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.Fórmula:C15H12Cl2N4OPureza:96.51% - ≥95%Cor e Forma:SolidPeso molecular:335.19Hydroflumethiazide
CAS:Hydroflumethiazide is a thiazide diuretic. It has also shown the activity of anti-hypertensive.Fórmula:C8H8F3N3O4S2Cor e Forma:Crystals SolidPeso molecular:331.29Bts 39542
CAS:Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.Fórmula:C16H11ClN4O3SCor e Forma:SolidPeso molecular:374.8Alilusem
CAS:Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.Fórmula:C17H15ClKN2O5SCor e Forma:SolidPeso molecular:433.92H100
CAS:H100 inhibits Cl- transport, mildly affects NaK2Cl cotransporter and Band 3 anion exchanger, not KCl cotransporter.Fórmula:C18H16N2O6SPureza:98%Cor e Forma:SolidPeso molecular:388.4BTG-1640
CAS:BTG-1640 is used potentially for the treatment of anxiety and panic disorder.Fórmula:C15H19NO2Cor e Forma:SolidPeso molecular:245.32NS-3736
CAS:NS-3736 is a chloride channel inhibitor that has been shown to prevent osteoclastic acidification and resorption.Fórmula:C15H9BrClF3N6OCor e Forma:SolidPeso molecular:461.62IAA-94
CAS:IAA-94 is an inhibitor of chloride channels, it binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM.Fórmula:C17H18Cl2O4Cor e Forma:SolidPeso molecular:357.23
