Canal de cloreto
Os canais de cloreto são proteínas de membrana que controlam o movimento dos íons cloreto através das membranas celulares, desempenhando um papel vital na manutenção do volume celular, excitabilidade elétrica e equilíbrio ácido-base. A desregulação dos canais de cloreto está associada a doenças como fibrose cística, epilepsia e distúrbios renais. Na CymitQuimica, oferecemos uma variedade de moduladores de canais de cloreto para apoiar sua pesquisa em transporte de íons, homeostase celular e mecanismos de doenças.
Foram encontrados 53 produtos para "Canal de cloreto".
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Stepronin
CAS:Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.Fórmula:C10H11NO4S2Pureza:99.59%Cor e Forma:White SolidPeso molecular:273.33Ref: TM-T21433
5mg48,00€1mL*10mM (DMSO)48,00€10mg71,00€25mg111,00€50mg187,00€100mg290,00€200mg410,00€R(+)-IAA-94
CAS:R(+)-IAA-94 (Methylindazone) blocks epithelial chloride channels; inhibits Nef-sdAb19 binding.Fórmula:C17H18Cl2O4Pureza:98.95% - 99.17%Cor e Forma:White SolidPeso molecular:357.23Losigamone
CAS:Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.Fórmula:C12H11ClO4Pureza:99.98%Cor e Forma:SolidPeso molecular:254.67ANO1-IN-1
CAS:ANO1-IN-1 blocks ANO1/2 channels (IC50: 2.56/15.43 μM) and hinders glioma cell growth.Fórmula:C18H28N2O2SPureza:99.93%Cor e Forma:SolidPeso molecular:336.49Ani9
CAS:Ani9 selectively blocks ANO1/TMEM16A with a 77 nM IC50, useful for ANO1 research and treating cancer, hypertension, pain, diarrhea, asthma.Fórmula:C17H17ClN2O3Pureza:99.73%Cor e Forma:White SolidPeso molecular:332.78Ref: TM-T26630
1mg37,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg124,00€25mg255,00€50mg430,00€100mg620,00€500mg1.333,00€ARN 11391
CAS:ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ionFórmula:C22H29N3O3Cor e Forma:SolidPeso molecular:383.49DIOA
CAS:DIOA acts as a potent antagonist of acid-sensitive outwardly rectifying (ASOR) anion channels [1].Fórmula:C20H24Cl2O4Cor e Forma:SolidPeso molecular:399.31OADS
CAS:OADS is an inhibitor of ClC-ec1 with low micromolar affinity. OADS has no specific effect on a CLC channel (ClC-1).Fórmula:C30H42N2O8S2Cor e Forma:SolidPeso molecular:622.79PAT1inh-B01
CAS:PAT1inh-B01, a selective SLC26A6 inhibitor, impedes PAT1 (a Cl-/HCO3- exchanger) activity, with an IC50 of 350 nM, effectively inhibiting anion exchange.Fórmula:C22H18BrF3N6O2Cor e Forma:SolidPeso molecular:535.32PAT1inh-A0030
CAS:PAT1inh-A0030 is a selective inhibitor of PAT1 (SLC26A6) with an IC 50 value of 1.0 μM. It inhibits fluid absorption in the ileum of wild-type and cystic fibrosis (CF) mice (CftrdelF508/delF508) in a closed-loop model of intestinal fluid absorption and can be used in the study of intestinal diseases related to CF [1].Fórmula:C17H18N4O3Cor e Forma:SolidPeso molecular:326.35S9-A13
CAS:S9-A13 is a potent and selective inhibitor of SLC26A9, exhibiting an IC50 of 90.9 nM without inhibiting other members of the SLC26 family, such as SLC26A3, SLC26A4, and SLC26A6. It also inhibits the SLC26A9 Cl- current in cells lacking CFTR expression.Fórmula:C20H18ClN3O2SCor e Forma:SolidPeso molecular:399.89DFBTA
DFBTA inhibits ANO1 with IC50 of 24 nM, effectively treating inflammatory pain orally.Fórmula:C18H10ClF2NO3SCor e Forma:SolidPeso molecular:393.79NMD670
CAS:NMD670 is an orally active, partial inhibitor of the skeletal muscle-specific chloride channel ClC-1. It enhances muscle excitability and neuromuscular transmission, restoring muscle function and mobility. NMD670 has a favorable safety profile and improves muscle function in rats, particularly in an MG rat model [1].Fórmula:C12H10BrNO4Cor e Forma:SolidPeso molecular:312.12
