ATPase
As ATPases são enzimas que catalisam a decomposição do ATP em ADP e um íon fosfato livre, uma reação que libera energia usada para impulsionar muitos processos dentro da célula, incluindo o transporte ativo através das membranas. As ATPases desempenham papéis cruciais na manutenção da homeostase celular, equilíbrio de pH e gradientes iônicos. Disfunções na atividade da ATPase estão associadas a doenças como insuficiência cardíaca, hipertensão e neurodegeneração. Na CymitQuimica, fornecemos inibidores e moduladores de ATPase de alta qualidade para apoiar sua pesquisa em energética celular, transporte de membranas e patologia de doenças.
Foram encontrados 100 produtos de "ATPase"
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Dicirenone
CAS:Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renalFórmula:C26H36O5Pureza:99.1%Cor e Forma:SolidPeso molecular:428.56ATPase-IN-2
CAS:ATPase-IN-2: ATPase inhibitor (IC50 = 0.9μM), also blocks C. difficile toxin B (AC50 = 30.91μM). Used in ATP research.Fórmula:C22H20N2O4Cor e Forma:SolidPeso molecular:376.41Istaroxime hydrochloride
CAS:Istaroxime hydrochloride (PST2744 hydrochloride) is a Na+/K+-ATPase inhibitor and SERCA 2 activator, and is a novel positive inotropic compound.Fórmula:C21H33ClN2O3Cor e Forma:SolidPeso molecular:396.95FSBA hydrochloride
CAS:FSBA hydrochloride(5'-p-Fluorosulfonylbenzoyladenosine) is an ATP analogue serving as an affinity probe for the ATP site of Na/K-ATPase.Fórmula:C17H17ClFN5O7SPureza:97.96%Cor e Forma:SolidPeso molecular:489.86Istaroxime
CAS:Istaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM).Fórmula:C21H32N2O3Pureza:98%Cor e Forma:SolidPeso molecular:360.49Leminoprazole
CAS:<p>Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.</p>Fórmula:C19H23N3OSPureza:99.08% - 99.56%Cor e Forma:SolidPeso molecular:341.47Tiludronate disodium
CAS:Tiludronate disodium: osteoclast inhibitor for metabolic bone disorder research.Fórmula:C7H7ClNa2O6P2SPureza:>99.99% - >99.99%Cor e Forma:Fine White To Off-White Crystalline PowderPeso molecular:362.57SCH28080
CAS:SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potentFórmula:C17H15N3OPureza:99.24%Cor e Forma:SolidPeso molecular:277.32FR-167356
CAS:<p>FR-167356 inhibits a3 isoform H⁺-ATPase (IC50: 170-370 nM), targeting osteoclasts, kidneys, macrophages; reduces B16-F10 bone metastasis.</p>Fórmula:C19H17Cl2NO3Pureza:98.44% - 99.74%Cor e Forma:SolidPeso molecular:378.25AGN-201904
CAS:AGN-201904 is a proton pump inhibitor, an omeprazole prodrug, which delays aging and may be used for the prevention and treatment of peptic ulcers.Fórmula:C25H25N3O8S2Pureza:97.32%Cor e Forma:SolidPeso molecular:559.61SKF96067
CAS:SKF96067 is a reversible gastric H+/K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.Fórmula:C21H22N2O2Pureza:99.89%Cor e Forma:SolidPeso molecular:334.41NC-1300-B
CAS:NC-1300-B inhibits H(+)-K(+)-ATPase and is used in the study of gastric ulcers.Fórmula:C17H19N3OSPureza:99.50%Cor e Forma:SolidPeso molecular:313.42BMS-199264 hydrochloride
CAS:<p>BMS-199264 hydrochloride is selective inhibitor of mitochondrial F1F0 ATP hydrolase,inhibit decline of ATP and myocardial necrosis during myocardial ischemia.</p>Fórmula:C26H32Cl2N4O4SPureza:99.86%Cor e Forma:SolidPeso molecular:567.53Ro 18-5364
CAS:Ro 18-5364 is a potent inhibitor of the gastric (H+ + K+)-ATPase with an apparent Ki of 0.1 μM at pH 6.Fórmula:C22H25N3O3SPureza:98%Cor e Forma:SolidPeso molecular:411.523′-Acetate-ATP
CAS:3’-Acetate-ATP, an analogue of ATP and its acetylation product, exhibits maximum ultraviolet absorption at 259 nm in neutral aqueous solutions.Fórmula:C12H18N5O14P3Cor e Forma:SolidPeso molecular:549.22ATP synthase inhibitor 2
CAS:<p>ATP synthase inhibitor 2 blocks P. aeruginosa ATP synthase; IC50=10 μg/mL, fully inhibits at 128 μg/mL.</p>Fórmula:C21H22N2O3SCor e Forma:SolidPeso molecular:382.48Hsp90-IN-38
CAS:<p>Hsp90-IN-38 (compound 20m) is an inhibitor of HSP90 (heat shock protein). It demonstrates a strong binding affinity to HSP90 with a Kd of 87 nM. The compound inhibits ATPase activity with an IC50 of 0.13 μM. Hsp90-IN-38 also shows inhibitory effects on HCT116, MCF-7, SKBr3, K562, and A549 cells with IC50 values of 0.187, 0.072, 0.105, 0.403, and 0.031 μM, respectively.</p>Fórmula:C28H35N3O5Cor e Forma:SolidPeso molecular:493.595Suloctidil HCl
CAS:Suloctidil HCl is a peripheral vascular dilator.Fórmula:C20H36ClNOSCor e Forma:SolidPeso molecular:374.02Antimalarial agent 7
Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.Fórmula:C23H22F2N4O3Cor e Forma:SolidPeso molecular:440.44Vonoprazan fumarate
CAS:<p>Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.</p>Fórmula:C17H16FN3O2S·C4H4O4Pureza:99.16% - 99.98%Cor e Forma:SolidPeso molecular:461.46
