Receptor CGRP
Os receptores de CGRP estão envolvidos na transmissão da dor e na regulação do fluxo sanguíneo. O CGRP é um neuropeptídeo que desempenha um papel crítico na fisiopatologia da enxaqueca, dilatando os vasos sanguíneos e modulando as vias de sinalização da dor. Alvejar os receptores de CGRP tornou-se uma abordagem promissora no desenvolvimento de terapias para enxaqueca. Na CymitQuimica, oferecemos uma variedade de moduladores de receptores de CGRP para apoiar sua pesquisa em manejo da dor, neurobiologia e saúde vascular.
Foram encontrados 55 produtos para "Receptor CGRP".
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Erenumab
CAS:Erenumab: human antibody blocking CGRP receptors to prevent migraines.Pureza:99.43% (SEC-HPLC) - > 95%Cor e Forma:Transparent LiquidPeso molecular:146.2 kDaPHM-27 (human) acetate
PHM-27 (human) acetate is the endogenous peptide product of prepro-VIP (human), an agonist of the calcitonin receptor (EC 50 = 11 nM). enhanced insulin secretion.Fórmula:C137H215F3N34O42SPureza:99.20%Cor e Forma:SolidPeso molecular:3099.44β-CGRP (mouse)
β-CGRP (mouse), a calcitonin gene-related peptide, induces vasodilation and is applicable in research areas including cardiovascular, pro-inflammatory, migraine, and metabolic studies.Fórmula:C165H265N49O55S2Cor e Forma:SolidPeso molecular:3879.29Cagrilintide acetate
.Cagrilintide is a long-acting amylin analog,treat diabetes and obesity by reducing appetite through activation of the AMY3R and calcitonin receptor.Fórmula:C196H316N54O61S2Pureza:99.88%Cor e Forma:White SolidPeso molecular:4469.06MK-3207
CAS:MK-3207 is a potent, oral CGRP receptor antagonist with high selectivity for human and monkey receptors, inhibiting blood flow in vivo.Fórmula:C31H29F2N5O3Cor e Forma:White SolidPeso molecular:557.59CGRP antagonist 6
CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.Cor e Forma:Odour SolidAdrenomedullin (1-50), rat
CAS:Rat adrenomedullin (1-50) is a 50-AA peptide; induces arterial vasodilation by activating CGRP1 receptors.Fórmula:C248H381N77O75S5Pureza:98%Cor e Forma:SolidPeso molecular:5729.5Adrenomedullin (AM) (22-52), human
CAS:Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.Fórmula:C159H252N46O48Pureza:98%Cor e Forma:SolidPeso molecular:3576.04HCGRP-(8-37)
CAS:Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonistFórmula:C139H230N44O38Pureza:98%Cor e Forma:SolidPeso molecular:3125.59Olcegepant hydrochloride
CAS:Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a selective calcitonin gene-related peptide 1 (CGRP1) receptor antagonist.Fórmula:C38H48Br2ClN9O5Pureza:99.69%Cor e Forma:SolidPeso molecular:906.11CGRP 8-37 (rat)
CAS:CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.Fórmula:C138H224N42O41Pureza:99.28%Cor e Forma:SolidPeso molecular:3127.51α-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions andFórmula:C162H262N50O52S2·C2HF3O2Pureza:98%Cor e Forma:SolidAdrenomedullin (AM) (22-52), human acetate
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and anFórmula:C161H256N46O50Pureza:99.72%Cor e Forma:SolidPeso molecular:3636.09CRSP-1
CAS:Central CT receptor agonist, 350x stronger than CT, no CGRP or adrenomedullin action, inhibits osteoclasts, affects rat feeding, body temp, and calcium.Fórmula:C175H294N54O49S5Pureza:98%Cor e Forma:SolidPeso molecular:4098.88Calcitonin (human)
CAS:Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.Fórmula:C151H226N40O45S3Pureza:98%Cor e Forma:White Lyophilized PowderPeso molecular:3417.87Vazegepant
CAS:Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research.Fórmula:C36H46N8O3Pureza:98.61% - 99.98%Cor e Forma:White SolidPeso molecular:638.80Ref: TM-T38734
1mg90,00€5mg215,00€1mL*10mM (DMSO)289,00€10mg318,00€25mg537,00€50mg767,00€100mg1.054,00€α-CGRP, rat
CAS:Endogenous neuropeptide, potent vasodilatorFórmula:C162H262N50O52S2Pureza:98%Cor e Forma:SolidPeso molecular:3806.25β-CGRP, human
CAS:β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascularFórmula:C162H267N51O48S3Pureza:98%Cor e Forma:SolidPeso molecular:3793.41(3R,5R,6S)-Atogepant
(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.Fórmula:C29H23F6N5O3Cor e Forma:SolidPeso molecular:603.52PHM-27 (human)
CAS:Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.Fórmula:C135H214N34O40SPureza:98%Cor e Forma:SolidPeso molecular:2985.44Adrenomedullin (AM) (22-52), human TFA
Adrenomedullin (AM) human (22-52) is a truncated NH2 TFA-modified adrenal medullary receptor antagonist.Fórmula:C161H253N46F3O50Pureza:98%Cor e Forma:SolidPeso molecular:3690.06Calcitonin (human) acetate
CAS:Calcitonin (human) acetate (21215-62-3, free base) is a synthetic polypeptide hormone composed of 32 amino acids.Fórmula:C153H230N40O47S3Pureza:99.46%Cor e Forma:White SolidPeso molecular:3477.91MK-8825
CAS:MK-8825 is a CGRP receptor antagonist.Fórmula:C31H30F2N6O3Cor e Forma:SolidPeso molecular:572.61Calcitonin Gene Related Peptide (CGRP) II, rat
CAS:CGRP II is a potent vasodilator that boosts pancreatic enzyme levels by activating β-cell receptors.Fórmula:C163H267N51O50S2Pureza:98%Cor e Forma:SolidPeso molecular:3805.31Adrenomedullin (11-50), rat
CAS:Adrenomedullin 11-50 rat is a peptide, stimulates CGRP1 receptor for vasodilation, used in bone growth research.Fórmula:C194H304N58O59S4Pureza:98%Cor e Forma:SolidPeso molecular:4521.17Ubrogepant-D5
Ubrogepant-D5 is the deuterium-labeled version of Ubrogepant. It is an orally active and selective antagonist of the calcitonin gene-related peptide receptor (CGRP). Ubrogepant (T17194) exhibits high affinity for CGRP receptors in humans and rhesus monkeys, effectively blocking the cAMP response induced by α-CGRP stimulation. This compound is utilized in studies focused on acute migraine.Cor e Forma:Odour Solidα-CGRP(human)
CAS:Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.Fórmula:C163H267N51O49S2Pureza:98%Cor e Forma:SolidPeso molecular:3789.33Adrenomedullin (16-31), human
CAS:Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).Fórmula:C82H129N25O21S2Pureza:98%Cor e Forma:SolidPeso molecular:1865.19Galcanezumab
CAS:Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.Pureza:> 95%Cor e Forma:Transparent LiquidPeso molecular:144.08 kDaα-CGRP(human) TFA
α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as aFórmula:C165H268F3N51O51S2Cor e Forma:SolidPeso molecular:3903.33Adrenomedullin (16-31), human TFA
Human adrenomedullin (16-31) TFA, fragment 16-31, binds CGRP1 receptor, raises rat blood pressure, not cats’.Fórmula:C84H130F3N25O23S2Cor e Forma:SolidPeso molecular:1979.21Adrenotensin (human)
CAS:Adrenotensin: human 153-185 fragment of Adrenomedullin precursor, a 52-amino acid peptide in CGRP hormone family.Fórmula:C143H224N42O43Cor e Forma:SolidPeso molecular:3219.56Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Rat CGRP II TFA: potent vasodilator and CGRP receptor activator for cardiovascular research.Fórmula:C165H268F3N51O52S2Cor e Forma:SolidPeso molecular:3919.33Telcagepant
CAS:Telcagepant (MK-0974) is an oral calcitonin gene-related peptide receptor (CGRP) antagonist that blocks CGRP receptors, migraines and for pain relief.Fórmula:C26H27F5N6O3Pureza:98.98% - 98.98%Cor e Forma:SolidPeso molecular:566.52Calcitonin (salmon)
CAS:Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.Fórmula:C145H240N44O48S2Pureza:99.41% - 99.80%Cor e Forma:SolidPeso molecular:3431.85SUN B8155
CAS:SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.Fórmula:C14H15N3O3Pureza:99.38% - 99.99%Cor e Forma:Yellow SolidPeso molecular:273.29Rimegepant
CAS:View and buy Rimegepant from TargetMol.BMS-927711 is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.Cited in 1 publications.Fórmula:C28H28F2N6O3Pureza:99.1% - 99.99%Cor e Forma:White SolidPeso molecular:534.56Ref: TM-T4610
10mgA consultar25mgA consultar50mgA consultar100mgA consultar200mgA consultar1mg52,00€5mg92,00€1mL*10mM (DMSO)105,00€β-CGRP, human acetate
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptorFórmula:C164H271N51O50S3Pureza:99.35%Cor e Forma:SolidPeso molecular:3853.46Olcegepant
CAS:Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4Fórmula:C38H47Br2N9O5Pureza:96.08% - 97.24%Cor e Forma:SolidPeso molecular:869.65BCTC
CAS:BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)Fórmula:C20H25ClN4OPureza:99.21% - 99.74%Cor e Forma:White SolidPeso molecular:372.89Vazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Fórmula:C36H47ClN8O3Pureza:98.93%Cor e Forma:White SolidPeso molecular:675.3Calcitonin(salmon) Acetate(47931-85-1(free base))
Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5Fórmula:C147H243N44O50S2Pureza:99.29% - 99.63%Cor e Forma:White SolidPeso molecular:3490.94HCGRP-(8-37) acetate
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.Fórmula:C141H234N44O40Pureza:99.53%Cor e Forma:SolidPeso molecular:3185.64Atogepant
CAS:Atogepant (MK-8031) is an orally available, selective and potent calcitonin gene-related peptide receptor (CGRP) antagonist for the study of migraine.Fórmula:C29H23F6N5O3Pureza:99.66%Cor e Forma:SolidPeso molecular:603.52Ref: TM-T26682
1mg147,00€5mg250,00€10mg313,00€1mL*10mM (DMSO)334,00€25mg620,00€50mg1.108,00€100mg1.611,00€200mg2.178,00€Eptinezumab
CAS:Eptinezumab is a humanised monoclonal antibody targeting CGRP (calcitonin gene-related peptide), which prevents CGRP binding to its receptor, migraine.Pureza:95% - 96.9% (SDS-PAGE); 99.8% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:143.27 kDaFremanezumab
CAS:Fremanezumab (TEV-48125) is a humanised monoclonal antibody targeting CGRP, capable of neutralising human, mouse and rat CGRP, migraine.Pureza:95% - 97.6% (SDS-PAGE); 95.9% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.49 kDaCGRP antagonist 1
CAS:CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for theFórmula:C29H26N4O4Pureza:99.55%Cor e Forma:SolidPeso molecular:494.54Ubrogepant
CAS:Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Fórmula:C29H26F3N5O3Pureza:99.45% - 99.78%Cor e Forma:Yellow SolidPeso molecular:549.54Ref: TM-T17194
1mg144,00€5mg358,00€1mL*10mM (DMSO)432,00€10mg565,00€25mg880,00€50mg1.161,00€100mg1.594,00€Rimegepant sulfate hydrate
CAS:Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.Fórmula:C56H64F4N12O13SCor e Forma:SolidPeso molecular:1221.2526
