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Receptor CGRP

Receptor CGRP

Os receptores de CGRP estão envolvidos na transmissão da dor e na regulação do fluxo sanguíneo. O CGRP é um neuropeptídeo que desempenha um papel crítico na fisiopatologia da enxaqueca, dilatando os vasos sanguíneos e modulando as vias de sinalização da dor. Alvejar os receptores de CGRP tornou-se uma abordagem promissora no desenvolvimento de terapias para enxaqueca. Na CymitQuimica, oferecemos uma variedade de moduladores de receptores de CGRP para apoiar sua pesquisa em manejo da dor, neurobiologia e saúde vascular.

Foram encontrados 51 produtos de "Receptor CGRP"

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  • Adrenomedullin (AM) (22-52), human acetate


    <p>Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and an</p>
    Fórmula:C161H256N46O50
    Pureza:99.42%
    Cor e Forma:Solid
    Peso molecular:3636.09
  • α-CGRP (mouse, rat) TFA


    <p>α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and</p>
    Fórmula:C162H262N50O52S2·C2HF3O2
    Pureza:98%
    Cor e Forma:Solid
  • Calcitonin-13C6,15N4 TFA


    <p>Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.</p>
    Fórmula:C1401C5H240N4315NO48S2·5C2HF3O2
    Cor e Forma:Solid
    Peso molecular:4007.93
  • Galcanezumab

    CAS:
    <p>Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.</p>
    Pureza:> 95%
    Cor e Forma:Liquid
    Peso molecular:144.08 kDa
  • CGRP antagonist 6


    <p>CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.</p>
    Cor e Forma:Odour Solid
  • Adrenomedullin (1-50), rat

    CAS:
    <p>Rat adrenomedullin (1-50) is a 50-AA peptide; induces arterial vasodilation by activating CGRP1 receptors.</p>
    Fórmula:C248H381N77O75S5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:5729.5
  • Adrenomedullin (AM) (22-52), human

    CAS:
    <p>Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.</p>
    Fórmula:C159H252N46O48
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3576.04
  • HCGRP-(8-37)

    CAS:
    <p>Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist</p>
    Fórmula:C139H230N44O38
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3125.59
  • Calcitonin (human)

    CAS:
    <p>Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.</p>
    Fórmula:C151H226N40O45S3
    Pureza:98%
    Cor e Forma:White Lyophilized Powder
    Peso molecular:3417.87
  • α-CGRP, rat

    CAS:
    <p>Endogenous neuropeptide, potent vasodilator</p>
    Fórmula:C162H262N50O52S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3806.25
  • β-CGRP, human

    CAS:
    <p>β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular</p>
    Fórmula:C162H267N51O48S3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3793.41
  • SUN B8155

    CAS:
    <p>SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.</p>
    Fórmula:C14H15N3O3
    Pureza:99.38% - 99.38%
    Cor e Forma:Solid
    Peso molecular:273.29
  • Telcagepant

    CAS:
    <p>Telcagepant (MK-0974) is an oral calcitonin gene-related peptide receptor (CGRP) antagonist that blocks CGRP receptors, migraines and for pain relief.</p>
    Fórmula:C26H27F5N6O3
    Pureza:98.98% - 98.98%
    Cor e Forma:Solid
    Peso molecular:566.52
  • Calcitonin (salmon)

    CAS:
    <p>Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.</p>
    Fórmula:C145H240N44O48S2
    Pureza:99.41% - 99.80%
    Cor e Forma:Powder
    Peso molecular:3431.85
  • Rimegepant

    CAS:
    <p>View and buy Rimegepant from TargetMol.BMS-927711 is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.Cited in 1 publications.</p>
    Fórmula:C28H28F2N6O3
    Pureza:99.1% - 99.99%
    Cor e Forma:Solid
    Peso molecular:534.56
  • BCTC

    CAS:
    <p>BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)</p>
    Fórmula:C20H25ClN4O
    Pureza:99.21%
    Cor e Forma:Solid
    Peso molecular:372.89
  • Calcitonin(salmon) Acetate(47931-85-1(free base))


    <p>Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5</p>
    Fórmula:C145H240N44O48S2
    Pureza:99.29%
    Cor e Forma:Solid
    Peso molecular:3431.85
  • Olcegepant

    CAS:
    <p>Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4</p>
    Fórmula:C38H47Br2N9O5
    Pureza:96.08% - 97.24%
    Cor e Forma:Solid
    Peso molecular:869.65
  • HCGRP-(8-37) acetate


    <p>HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.</p>
    Fórmula:C141H234N44O40
    Pureza:99.29%
    Cor e Forma:Solid
    Peso molecular:3185.64
  • Vazegepant hydrochloride

    CAS:
    <p>Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.</p>
    Fórmula:C36H47ClN8O3
    Pureza:98.93%
    Cor e Forma:Solid
    Peso molecular:675.3