Canal de Sódio
Os canais de sódio são proteínas de membrana essenciais que permitem a passagem de íons de sódio (Na+) através da membrana celular, gerando e propagando sinais elétricos em neurônios, células musculares e outros tecidos excitáveis. Esses canais são vitais para a iniciação e condução de potenciais de ação, sendo cruciais em processos como a transmissão de impulsos nervosos, contração muscular e função cardíaca. A desregulação dos canais de sódio pode levar a distúrbios neurológicos, arritmias e condições de dor crônica. Na CymitQuimica, oferecemos uma variedade de moduladores de canais de sódio para apoiar sua pesquisa em neurobiologia, cardiologia e manejo da dor.
Foram encontrados 202 produtos de "Canal de Sódio"
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Disopyramide
CAS:<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Fórmula:C21H29N3OPureza:99.62%Cor e Forma:SolidPeso molecular:339.47LTGO-33
CAS:<p>LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.</p>Fórmula:C21H17F4N3O3SPureza:97.6%Cor e Forma:SoildPeso molecular:467.44Veratridine
CAS:<p>Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.</p>Fórmula:C36H51NO11Pureza:98.07% - 99.27%Cor e Forma:Yellowish-White Amorphous Powder PowderPeso molecular:673.79GpTx-1 TFA
<p>GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.</p>Cor e Forma:Odour SolidLifarizine FA
<p>Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.</p>Fórmula:C30H34N4O2Pureza:99.55%Cor e Forma:SolidPeso molecular:482.62Indenebart
<p>Indenebart is a humanized IgG1λ2 monoclonal antibody targeting SNCA, with HumanIgG1lambda2, Isotype Control serving as the corresponding isotype control.</p>Cor e Forma:Odour LiquidPF-06456384 trihydrochloride
CAS:<p>PF-06456384 trihydrochloride is a selective NaV1.7 inhibitor acting through protein-ligand binding. intravenous infusion and pain research.</p>Fórmula:C35H35Cl3F3N7O3S2Pureza:99.16%Cor e Forma:SolidPeso molecular:829.18Huwentoxin-IV
CAS:<p>Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.</p>Fórmula:C174H278N52O51S6Pureza:98%Cor e Forma:SolidPeso molecular:4106.79Halazone
CAS:<p>Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.</p>Fórmula:C7H5Cl2NO4SPureza:98.64%Cor e Forma:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Peso molecular:270.09SLC26A3-IN-2
CAS:<p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>Fórmula:C19H13ClN2O2SPureza:99.86%Cor e Forma:SolidPeso molecular:368.84Zandatrigine
CAS:<p>Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy</p>Fórmula:C22H25FN4O2S2Pureza:99.98%Cor e Forma:SolidPeso molecular:460.59Amlenetug
<p>Amlenetug is a humanized IgG1κ antibody targeting SNCA, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.</p>Cor e Forma:Odour LiquidMepivacaine hydrochloride
CAS:<p>Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.</p>Fórmula:C15H22N2O·HClPureza:98.76% - 99.94%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:282.81Trapencaine
CAS:<p>Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.</p>Fórmula:C22H34N2O3Pureza:98.96%Cor e Forma:SolidPeso molecular:374.52Zoniporide
CAS:<p>Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits platelet swelling and can be used in the study of cardiovascular diseases.</p>Fórmula:C17H16N6OPureza:99.74%Cor e Forma:SolidPeso molecular:320.351-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS:<p>1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.</p>Fórmula:C6H8N2OPureza:99.92%Cor e Forma:SolidPeso molecular:124.14Benzonatate (PEGn)
CAS:<p>Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.</p>Fórmula:(C2H4O)nC12H17NO2Cor e Forma:Solid5-Tridecanol
CAS:<p>5-Tridecanol blocks ion flux in sodium channels.</p>Fórmula:C13H28OPureza:97.87%Cor e Forma:SolidPeso molecular:200.36APETx2
CAS:<p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>Fórmula:C196H280N54O61S6Pureza:98%Cor e Forma:SolidPeso molecular:4561.06Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Fórmula:C272H429N85O84S10Pureza:98%Cor e Forma:SolidPeso molecular:6554.51
