Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 543 produtos de "Canais de Cálcio"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Mast cell degranulating peptide (28-49)
CAS:<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Fórmula:C110H196N40O24S4Pureza:98%Cor e Forma:SolidPeso molecular:2591.25O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine
CAS:O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine is a major metabolite of the calcium channel inhibitor amlodipine .1Fórmula:C20H20ClNO7Cor e Forma:SolidPeso molecular:421.83Nesiritide acetate
CAS:Nesiritide, a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide, enhances vasorelaxation ex vivo in porcine hearts from an acute coronary occlusion model when given as a 2 µg/kg bolus dose followed by a 0.01 µg/kg per minute infusion, facilitated by the calcium ionophore A23187. Formulations containing nesiritide have been utilized in managing congestive heart failure.Fórmula:C143H244N50O42S4C2H4O2Cor e Forma:SolidPeso molecular:3524.1Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.Cor e Forma:LiquidChlorocresol
CAS:Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Fórmula:C7H7ClOCor e Forma:SolidPeso molecular:142.58ω-Agatoxin TK
CAS:<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Fórmula:C215H337N65O70S10Pureza:98%Cor e Forma:SolidPeso molecular:5273.02PACAP-38 (31-38), human, mouse, rat
CAS:PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine productionFórmula:C47H83N17O11Pureza:98%Cor e Forma:SolidPeso molecular:1062.27Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Fórmula:C153H266N38O38S2Cor e Forma:SolidPeso molecular:3310.11sFTX-3.3
CAS:sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.Fórmula:C12H29N7OCor e Forma:SolidPeso molecular:287.412MMK 1
CAS:Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Fórmula:C75H123N19O18SPureza:98%Cor e Forma:SolidPeso molecular:1610.972-Nitrobenzoic acid
CAS:2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.Fórmula:C7H5NO4Pureza:99.97%Cor e Forma:SoildPeso molecular:167.12Kurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)Fórmula:C324H478N94O90S8Pureza:98%Cor e Forma:SolidPeso molecular:7386.36SG-094
CAS:<p>SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.</p>Fórmula:C30H29NO3Pureza:97.06%Cor e Forma:SoildPeso molecular:451.56(±)5(6)-DiHETE
CAS:Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.472Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Fórmula:C24H35Cl2N3O4SPureza:99.33% - 99.76%Cor e Forma:SoildPeso molecular:532.523Ethacrynic acid D5
CAS:Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.Fórmula:C13H12Cl2O4Pureza:98%Cor e Forma:SolidPeso molecular:308.17Triphenylethylene
CAS:Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C20H16Cor e Forma:White PowderPeso molecular:256.34UK-59811 hydrochloride
CAS:UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.Fórmula:C22H30BrClN2O5Cor e Forma:SolidPeso molecular:517.85ω-Conotoxin GVIA
CAS:Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.Fórmula:C120H182N38O43S6Pureza:98%Cor e Forma:SolidPeso molecular:3037Ziconotide
CAS:Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.Fórmula:C102H172N36O32S7Pureza:98%Cor e Forma:White PowderPeso molecular:2639.13
![O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT35602.webp&w=3840&q=75)
