Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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BX430
CAS:BX430 is used for chronic pain and cardiovascular disease and it is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonistFórmula:C15H15Br2N3OPureza:97.34%Cor e Forma:SolidPeso molecular:413.115,5-Dimethyloxazolidine-2,4-dione
CAS:5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE.Fórmula:C5H7NO3Pureza:99.12%Cor e Forma:Drypowder PelletslargecrystalsPeso molecular:129.11CRAC intermediate 2
CAS:CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis.Fórmula:C11H7F6N3Pureza:99.69%Cor e Forma:SolidPeso molecular:295.18GSK-7975A
CAS:GSK-7975A is a potent and orally available inhibitor of CRAC channel.Fórmula:C18H12F5N3O2Pureza:98.92%Cor e Forma:SolidPeso molecular:397.3Ref: TM-T15423
1mg44,00€2mg58,00€5mg93,00€10mg137,00€25mg264,00€50mg399,00€100mg602,00€500mg1.254,00€1mL*10mM (DMSO)93,00€Bupivacaine hydrochloride
CAS:Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Fórmula:C18H28N2O·HClPureza:99.89% - 99.9%Cor e Forma:SolidPeso molecular:324.89Caloxin 2A1 TFA
<p>Caloxin 2A1 TFA is a PM Ca2+ pump inhibitor that inhibits human red blood cell Ca2+-Mg2+-ATPase leakage.</p>Fórmula:C66H92F3N19O24Pureza:99.89%Cor e Forma:SolidPeso molecular:1592.55Strontium ranelate
CAS:Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.Fórmula:C12H6N2O8S·2SrPureza:98.97%Cor e Forma:Crystalline SolidPeso molecular:513.49Nimodipine
CAS:Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.Fórmula:C21H26N2O7Pureza:99.64% - 99.79%Cor e Forma:SolidPeso molecular:418.44GV-58
CAS:GV-58 agonizes N/P-Q-type Ca2+ channels (EC50: 7.21/8.81 μM) with 20x less inhibition on CDK kinases.Fórmula:C18H26N6OSPureza:97.36%Cor e Forma:SolidPeso molecular:374.5Ref: TM-T11517
1mg51,00€5mg144,00€10mg216,00€25mg432,00€50mg625,00€100mg873,00€500mg1.738,00€1mL*10mM (DMSO)159,00€Penfluridol
CAS:Penfluridol (TLP-607) is a highly potent antipsychotic.Fórmula:C28H27ClF5NOPureza:98.9% - 99.87%Cor e Forma:Off-White To White Crystalline PowderPeso molecular:523.97Catharanthine tartrate
CAS:Catharanthine tartrate (Catharanthine hemitartrate) is an alkaloid from periwinkle that inhibits voltage-gated L-type calcium channels and has antitumor effect.Fórmula:C25H30N2O8Pureza:99.91%Cor e Forma:SolidPeso molecular:486.51Nifedipine
CAS:Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent.Fórmula:C17H18N2O6Pureza:99.39% - 99.49%Cor e Forma:Yellow Crystals Physical Description Odorless Yellow Crystals Or Powder Tasteless (Ntp 1992)Peso molecular:346.33PACAP-38 (31-38), human, mouse, rat TFA
PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.Fórmula:C49H84F3N17O13Pureza:98%Cor e Forma:SolidPeso molecular:1176.29Isotachysterol 3
CAS:Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.Fórmula:C27H44OCor e Forma:SolidPeso molecular:384.64D-myo-Inositol-1,3-diphosphate (sodium salt)
CAS:<p>D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is an inositol phosphate involved in cellular signal transduction.</p>Fórmula:C6H12Na2O12P2Cor e Forma:SolidPeso molecular:384.08NSC156529
CAS:NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.Fórmula:C28H21ClS2Pureza:98%Cor e Forma:SolidPeso molecular:457.05Nesiritide
CAS:Nesiritide, recombinant human B-type natriuretic peptide, binds NPR-A/C with Kd 7.3/13 pM.Fórmula:C143H244N50O42S4Pureza:98%Cor e Forma:SolidPeso molecular:3464.04NAADP tetrasodium salt
CAS:Ca2+ mobilizing agentFórmula:C21H27N6O18P3Pureza:98%Cor e Forma:SolidPeso molecular:744.39D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
CAS:Ins(1,3,4,5)-P4, made via Ins(1,4,5)P3 phosphorylation, boosts calcium by opening ER and plasma membrane channels.Fórmula:C6H8Na8O18P4Cor e Forma:SolidPeso molecular:675.93Elgodipine
CAS:Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.Fórmula:C29H33FN2O6Pureza:99.84% - 99.98%Cor e Forma:SolidPeso molecular:524.58G-Glu-Ser
CAS:G-Glu-Ser is a calcium receptor activator and Flavor-enriching agent.Fórmula:C8H14N2O6Cor e Forma:SolidPeso molecular:234.21Ryanodine
CAS:Ryanodine: a diterpenoid modulating Ca2+ release via ryanodine receptors; concentration-dependent effects; found in Ryania speciosa; toxic.Fórmula:C25H35NO9Pureza:98%Cor e Forma:White SolidPeso molecular:493.553Cd1a
Cd1a, a β-toxin from the African spider Ceratogyrus darlingi, modulates calcium ion channels and inhibits human calcium ion channels (Ca v 2.2)(IC 50 2.6 μM) asCor e Forma:Odour SolidBTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Fórmula:C34H28N4O4Pureza:98.34%Cor e Forma:SolidPeso molecular:556.61Amlodipine aspartic acid impurity
CAS:Amlodipine aspartic acid: a calcium blocker with antihypertensive effects; contains specific impurities.Fórmula:C24H29ClN2O9Pureza:98%Cor e Forma:SolidPeso molecular:524.95ω-Conotoxin MVIIC
CAS:Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.Fórmula:C106H178N40O32S7Pureza:98%Cor e Forma:White Lyophilised SolidPeso molecular:2749Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Fórmula:C14H17N3O2SPureza:99.79% - 99.84%Cor e Forma:SolidPeso molecular:291.37Cavα2δ-IN-1
CAS:Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a KiFórmula:C18H27N5OCor e Forma:SolidPeso molecular:329.448Huwentoxin I
CAS:Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.Fórmula:C161H246N48O44S6Pureza:98%Cor e Forma:SolidPeso molecular:3750.36Mast cell degranulating peptide (28-49)
CAS:<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Fórmula:C110H196N40O24S4Pureza:98%Cor e Forma:SolidPeso molecular:2591.25O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine
CAS:O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine is a major metabolite of the calcium channel inhibitor amlodipine .1Fórmula:C20H20ClNO7Cor e Forma:SolidPeso molecular:421.83Nesiritide acetate
CAS:Nesiritide, a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide, enhances vasorelaxation ex vivo in porcine hearts from an acute coronary occlusion model when given as a 2 µg/kg bolus dose followed by a 0.01 µg/kg per minute infusion, facilitated by the calcium ionophore A23187. Formulations containing nesiritide have been utilized in managing congestive heart failure.Fórmula:C143H244N50O42S4C2H4O2Cor e Forma:SolidPeso molecular:3524.1Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.Cor e Forma:LiquidChlorocresol
CAS:Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Fórmula:C7H7ClOCor e Forma:SolidPeso molecular:142.58ω-Agatoxin TK
CAS:<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Fórmula:C215H337N65O70S10Pureza:98%Cor e Forma:SolidPeso molecular:5273.02PACAP-38 (31-38), human, mouse, rat
CAS:PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine productionFórmula:C47H83N17O11Pureza:98%Cor e Forma:SolidPeso molecular:1062.27Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Fórmula:C153H266N38O38S2Cor e Forma:SolidPeso molecular:3310.11sFTX-3.3
CAS:sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.Fórmula:C12H29N7OCor e Forma:SolidPeso molecular:287.412MMK 1
CAS:Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Fórmula:C75H123N19O18SPureza:98%Cor e Forma:SolidPeso molecular:1610.972-Nitrobenzoic acid
CAS:2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.Fórmula:C7H5NO4Pureza:99.97%Cor e Forma:SoildPeso molecular:167.12Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Fórmula:C24H35Cl2N3O4SPureza:99.33% - 99.76%Cor e Forma:SoildPeso molecular:532.523Kurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)Fórmula:C324H478N94O90S8Pureza:98%Cor e Forma:SolidPeso molecular:7386.36SG-094
CAS:<p>SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.</p>Fórmula:C30H29NO3Pureza:97.06%Cor e Forma:SoildPeso molecular:451.56(±)5(6)-DiHETE
CAS:Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.472Ethacrynic acid D5
CAS:Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.Fórmula:C13H12Cl2O4Pureza:98%Cor e Forma:SolidPeso molecular:308.17ω-Conotoxin GVIA
CAS:Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.Fórmula:C120H182N38O43S6Pureza:98%Cor e Forma:SolidPeso molecular:3037Triphenylethylene
CAS:Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C20H16Cor e Forma:White PowderPeso molecular:256.34UK-59811 hydrochloride
CAS:UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.Fórmula:C22H30BrClN2O5Cor e Forma:SolidPeso molecular:517.85Ziconotide
CAS:Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.Fórmula:C102H172N36O32S7Pureza:98%Cor e Forma:White PowderPeso molecular:2639.131-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS:<p>1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(</p>Fórmula:C5H10ClNO2Pureza:>99.99%Cor e Forma:SolidPeso molecular:151.59
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