Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 543 produtos de "Canais de Cálcio"
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KT-362 free base
CAS:KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.Fórmula:C22H28N2O3SPureza:99.91%Cor e Forma:SoildPeso molecular:400.53MMK 1
CAS:Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Fórmula:C75H123N19O18SPureza:98%Cor e Forma:SolidPeso molecular:1610.97Glutarimide
CAS:Compound PDK0025, with CAS No. 1121-89-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0025 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C5H7NO2Peso molecular:113.11Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Fórmula:C153H266N38O38S2Cor e Forma:SolidPeso molecular:3310.11Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Fórmula:C14H17N3O2SPureza:99.79% - 99.84%Cor e Forma:SolidPeso molecular:291.37Lnd 796
CAS:Lnd 796 is an aminosteroid related to LND 623.Fórmula:C27H45NO7Cor e Forma:SolidPeso molecular:495.65N-Palmitoyl Glycine
CAS:Acyl amides like AEA modulate pain/inflammation. PalGly, similar to N-acyl ethanolamines, inhibits nociception and induces calcium influx in cells.Fórmula:C18H35NO3Cor e Forma:SolidPeso molecular:313.48Catharanthine
CAS:Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).Fórmula:C21H24N2O2Pureza:99.11%Cor e Forma:White PowderPeso molecular:336.43CCT129957
CAS:CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity andFórmula:C17H15N3O3Pureza:99.69%Cor e Forma:SolidPeso molecular:309.32Ref: TM-T14903
1mg47,00€5mg87,00€10mg133,00€25mg233,00€50mg349,00€100mg525,00€500mg1.111,00€1mL*10mM (DMSO)97,00€(R)-(+)-Bay-K-8644
CAS:<p>(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.</p>Fórmula:C16H15F3N2O4Pureza:96.51% - 96.51%Cor e Forma:SolidPeso molecular:356.3TPC2-A1-N
CAS:TPC2-A1-N is a TPC2 small molecule agonist that can be used to detect different functions of TPC2 channels in intact cells.Fórmula:C17H9Cl2F3N2O2Pureza:99.86%Cor e Forma:SolidPeso molecular:401.17Norverapamil-d7 HCl
CAS:Norverapamil-d7 HCl (D591-d7 HCl) is a 2H-labeled Norverapamil HCl, a calcium channel blocker and P-gp inhibitor, also a coronary vasodilator.Fórmula:C26H37ClN2O4Cor e Forma:SolidPeso molecular:484.08(S)-Lercanidipine D3 hydrochloride
CAS:(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:651.21(R)-Nicardipine
CAS:(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Fórmula:C26H29N3O6Cor e Forma:SolidPeso molecular:479.53MRS1845
CAS:MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).Fórmula:C21H22N2O6Pureza:99.69%Cor e Forma:SolidPeso molecular:398.41Almorexant hydrochloride
CAS:Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Fórmula:C29H32ClF3N2O3Pureza:99.85%Cor e Forma:SolidPeso molecular:549.02β-Cyfluthrin
CAS:β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products.Fórmula:C22H18Cl2FNO3Cor e Forma:SolidPeso molecular:434.29YM-244769
CAS:YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3)Fórmula:C26H22FN3O3Pureza:95.62%Cor e Forma:SolidPeso molecular:443.47(R)-Lercanidipine-d3 hydrochloride
CAS:(R)-lercanidipine D3 hydrochloride is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride) is a calcium channel blocker.Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:651.21YM-244769 dihydrochloride
CAS:YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.Fórmula:C26H24Cl2FN3O3Pureza:98%Cor e Forma:SolidPeso molecular:516.39Nicardipine-d3 hydrochloride
CAS:Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.Fórmula:C26H30ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:519HSK16149
CAS:HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.Fórmula:C12H19NO2Cor e Forma:SolidPeso molecular:209.28(S)-Nicardipine
CAS:(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Fórmula:C26H29N3O6Cor e Forma:SolidPeso molecular:479.53Norverapamil-d7
CAS:Norverapamil D7 is a deuterium labeled Norverapamil . Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .Fórmula:C26H36N2O4Pureza:98%Cor e Forma:SolidPeso molecular:447.62Hexadecylphosphoserine TFA
Hexadecylphosphoserine is a type of phospholipid molecule that incorporates a long-chain alkyl group (hexadecyl) and a phosphatidylserine group, granting it high affinity for cell membranes. This compound exhibits antitumor activity by modulating [Ca++]i and related signaling pathways, making it useful for breast cancer research.Fórmula:C21H41F3NO8PCor e Forma:SolidPeso molecular:523.52Magnesium sulfate
CAS:Magnesium sulfate: anticonvulsant for eclampsia, tocolytic agent.Fórmula:MgSO4Pureza:98%Cor e Forma:SolidPeso molecular:120.37Etripamil
CAS:Etripamil is a fast-acting intranasal L-type calcium-channel blocker for Paroxysmal Supraventricular Tachycardia.Fórmula:C27H36N2O4Pureza:99.47% - 99.83%Cor e Forma:SolidPeso molecular:452.59Ref: TM-T15257
1mg55,00€2mg79,00€5mg116,00€10mg172,00€25mg311,00€50mg472,00€100mg707,00€200mg1.111,00€Dronedarone
CAS:Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Fórmula:C31H44N2O5SPureza:98.85% - 99.99%Cor e Forma:SolidPeso molecular:556.76HA-1004 HCl
CAS:HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.Fórmula:C12H17Cl2N5O2SCor e Forma:SolidPeso molecular:366.27JNJ-26990990
CAS:"JNJ-26990990: broad-spectrum anticonvulsant, less side effects than topiramate, potential for pain and depression treatment; Phase II in 2007."Fórmula:C9H10N2O2S2Pureza:97.37%Cor e Forma:SolidPeso molecular:242.32Ref: TM-T27673
1mg131,00€5mg286,00€10mg424,00€25mg702,00€50mg938,00€100mg1.311,00€1mL*10mM (DMSO)261,00€Efonidipine
CAS:Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.Fórmula:C34H38N3O7PPureza:98.35% - 99.47%Cor e Forma:SolidPeso molecular:631.66Bepridil hydrochloride
CAS:Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channelsFórmula:C24H35ClN2OPureza:99.45% - 99.68%Cor e Forma:SolidPeso molecular:4032,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Fórmula:C14H22O2Pureza:97.11%Cor e Forma:PelletslargecrystalsPeso molecular:222.32DHBP dibromide
CAS:DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor.Fórmula:C24H38Br2N2Pureza:99.73%Cor e Forma:Yellow To Yellow-Green Powder Or FlakesPeso molecular:514.38Propiverine hydrochloride
CAS:Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).Fórmula:C23H30ClNO3Pureza:99.93%Cor e Forma:White Crystalling PowerPeso molecular:403.94Levamlodipine hydrobromide
CAS:Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain.Fórmula:C20H26BrClN2O5Cor e Forma:SolidPeso molecular:489.79GSK1016790A
CAS:GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelialFórmula:C28H32Cl2N4O6S2Pureza:97.37% - 99.38%Cor e Forma:SolidPeso molecular:655.61Ref: TM-T6848
1mg37,00€2mg48,00€5mg72,00€10mg113,00€25mg240,00€50mg364,00€100mg540,00€1mL*10mM (DMSO)97,00€(+)-Kavain
CAS:(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.Fórmula:C14H14O3Pureza:97% - ≥95%Cor e Forma:White Fine PowderPeso molecular:230.26(±)-Praeruptorin A
CAS:(±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation.Fórmula:C21H22O7Pureza:98.9% - 99.73%Cor e Forma:SolidPeso molecular:386.40NS-638
CAS:NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).Fórmula:C15H11ClF3N3Pureza:98.44%Cor e Forma:SolidPeso molecular:325.72Suvecaltamide
CAS:Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.Fórmula:C20H23F3N2O2Pureza:99.29% - 99.70%Cor e Forma:SolidPeso molecular:380.4Azumolene sodium anhydrous
CAS:Azumolene sodium, a muscle relaxant, blocks calcium release from muscles and halts SOCE linked to RyR1 except when induced by thapsigargin.Fórmula:C13H8BrN4NaO3Cor e Forma:SolidPeso molecular:371.13SR33805
CAS:<p>SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)</p>Fórmula:C32H40N2O5SPureza:99.15%Cor e Forma:SolidPeso molecular:564.74Mirogabalin besylate
CAS:Mirogabalin besylate is an oral α2δ ligand for voltage-gated calcium channels, with Kd values of 13.5-47.6 nM across species.Fórmula:C18H25NO5SCor e Forma:SolidPeso molecular:367.46Efonidipine hydrochloride monoethanolate
CAS:Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.Fórmula:C36H45ClN3O8PPureza:>99.99%Cor e Forma:SolidPeso molecular:714.18Praeruptorin E
CAS:Praeruptorin C/E relaxes arteries, reduces heart contractility, acting like calcium blockers. D/E protect mice from acid lung injury by halting PMNs and IL-6.Fórmula:C24H28O7Pureza:98.04% - 99.95%Cor e Forma:SolidPeso molecular:428.47TGR5 Receptor Agonist
CAS:TGR5 is a potent TGR5(GPCR19) agonist.Fórmula:C18H14Cl2N2O2Pureza:99.77% - ≥95%Cor e Forma:SolidPeso molecular:361.22Ibutilide Fumarate
CAS:Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Fórmula:(C20H36N2O3S)2·C4H4O4Pureza:99.68% - 99.74%Cor e Forma:SolidPeso molecular:885.23Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Fórmula:C48H82O18Pureza:99.13% - 99.92%Cor e Forma:SolidPeso molecular:947.15Ref: TM-T2878
1mg37,00€5mg71,00€10mg99,00€25mg170,00€50mg260,00€100mg394,00€200mg570,00€1mL*10mM (DMSO)124,00€HC-056456
CAS:HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.Fórmula:C12H6N2O4S2Pureza:99.62% - 99.65%Cor e Forma:SolidPeso molecular:306.32Ref: TM-T4604
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg170,00€50mg274,00€100mg454,00€1mL*10mM (DMSO)77,00€
