Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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(+)-Kavain
CAS:(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.Fórmula:C14H14O3Pureza:97% - ≥95%Cor e Forma:White Fine PowderPeso molecular:230.26(±)-Praeruptorin A
CAS:(±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation.Fórmula:C21H22O7Pureza:98.9% - 99.73%Cor e Forma:SolidPeso molecular:386.40NP118809
CAS:<p>NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).</p>Fórmula:C32H32N2OPureza:97.74% - 98.68%Cor e Forma:SolidPeso molecular:460.61Manidipine
CAS:Manidipine (Iperten), a calcium channel blocker, which is dihydropyridine type. It is utilizedFórmula:C35H38N4O6Pureza:99.30%Cor e Forma:SolidPeso molecular:610.7NFAT Inhibitor-2
CAS:NFAT Inhibitor-2 is a compound used as a molecular building block.Fórmula:C22H20F2N2O4SPureza:97.37%Cor e Forma:SolidPeso molecular:446.47Azumolene
CAS:Azumolene (EU4093 free base)Fórmula:C13H9BrN4O3Pureza:98.1% - 98.35%Cor e Forma:SolidPeso molecular:349.14Ref: TM-T8815
2mg49,00€5mg73,00€10mg116,00€25mg235,00€50mg373,00€100mg562,00€500mg1.216,00€1mL*10mM (DMSO)82,00€Dantrolene sodium hemiheptahydrate
CAS:Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calciumFórmula:C14H9N4NaO5·5H2OPureza:99.72%Cor e Forma:Orange PowderPeso molecular:399.29NS-638
CAS:NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).Fórmula:C15H11ClF3N3Pureza:98.44%Cor e Forma:SolidPeso molecular:325.72Mirogabalin
CAS:<p>Mirogabalin (DS5565) is a calcium channel blocker with analgesic effects.</p>Fórmula:C12H19NO2Pureza:98.57%Cor e Forma:SolidPeso molecular:209.28TGR5 Receptor Agonist
CAS:TGR5 is a potent TGR5(GPCR19) agonist.Fórmula:C18H14Cl2N2O2Pureza:99.77% - ≥95%Cor e Forma:SolidPeso molecular:361.22Suvecaltamide
CAS:Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.Fórmula:C20H23F3N2O2Pureza:99.29% - 99.70%Cor e Forma:SolidPeso molecular:380.4HALOFUGINONE LACTATE
CAS:HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.Fórmula:C19H23BrClN3O6Pureza:99.70% - 99.96%Cor e Forma:SolidPeso molecular:504.8Ref: TM-T8785
2mg42,00€5mg59,00€10mg94,00€25mg130,00€50mg207,00€100mg309,00€200mg462,00€1mL*10mM (DMSO)66,00€Ruthenium Red
CAS:Ruthenium Red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria.Fórmula:Cl6H42N14O2Ru3Pureza:95%Cor e Forma:Purple PowderPeso molecular:786.34L-Phenylalanine
CAS:<p>L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.</p>Fórmula:C9H11NO2Pureza:99.37% - 99.87%Cor e Forma:Solid CrystallinePeso molecular:165.19ISX-9
CAS:ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.Fórmula:C11H10N2O2SPureza:97.81% - ≥95%Cor e Forma:SolidPeso molecular:234.27Ref: TM-T2003
2mg48,00€5mg72,00€10mg97,00€25mg155,00€50mg210,00€100mg378,00€500mg889,00€1mL*10mM (DMSO)79,00€Efonidipine hydrochloride monoethanolate
CAS:Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.Fórmula:C36H45ClN3O8PPureza:>99.99%Cor e Forma:SolidPeso molecular:714.18Ibutilide Fumarate
CAS:Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Fórmula:(C20H36N2O3S)2·C4H4O4Pureza:99.68% - 99.74%Cor e Forma:SolidPeso molecular:885.23Bifemelane
CAS:Bifemelane, a nootropic, releases Ca2+ from stores and enables its entry via channels for astrocyte research.Fórmula:C18H23NOCor e Forma:SolidPeso molecular:269.38Pyr6
CAS:Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influxFórmula:C17H9F7N4OPureza:98.89%Cor e Forma:SolidPeso molecular:418.27Z944
CAS:Z944 is a T-type calcium channel blocker.Fórmula:C19H27ClFN3O2Pureza:99.8% - 99.80%Cor e Forma:SolidPeso molecular:383.89Ref: TM-T29201
1mg52,00€5mg111,00€10mg180,00€25mg359,00€50mg530,00€100mg758,00€200mg1.035,00€1mL*10mM (DMSO)124,00€Ginsenoside Ro
CAS:Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist withFórmula:C48H76O19Pureza:98% - 99.66%Cor e Forma:SolidPeso molecular:957.11Nicardipine
CAS:Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.Fórmula:C26H29N3O6Pureza:99.56%Cor e Forma:SolidPeso molecular:479.52DHBP dibromide
CAS:DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor.Fórmula:C24H38Br2N2Pureza:99.73%Cor e Forma:Yellow To Yellow-Green Powder Or FlakesPeso molecular:514.38Propiverine hydrochloride
CAS:Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).Fórmula:C23H30ClNO3Pureza:99.93%Cor e Forma:White Crystalling PowerPeso molecular:403.94Levamlodipine hydrobromide
CAS:Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain.Fórmula:C20H26BrClN2O5Cor e Forma:SolidPeso molecular:489.79HC-056456
CAS:HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.Fórmula:C12H6N2O4S2Pureza:99.62% - 99.65%Cor e Forma:SolidPeso molecular:306.32Ref: TM-T4604
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg170,00€50mg274,00€100mg454,00€1mL*10mM (DMSO)77,00€HA-1004 HCl
CAS:HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.Fórmula:C12H17Cl2N5O2SCor e Forma:SolidPeso molecular:366.27Levamlodipine hydrochloride
CAS:Levamlodipine hydrochloride is a medication used to lower blood pressure and prevent chest pain.Fórmula:C20H26Cl2N2O5Cor e Forma:SolidPeso molecular:445.34Cycleanine
CAS:<p>Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.</p>Fórmula:C38H42N2O6Pureza:98.04% - 99.57%Cor e Forma:SolidPeso molecular:622.75Psoralenoside
CAS:Psoralenoside: a compound from Psoralea fruit; has estrogenic, osteoblastic, antitumor, and antibacterial properties.Fórmula:C17H18O9Pureza:99.03% - 99.49%Cor e Forma:SolidPeso molecular:366.32Ref: TM-TN1008
1mg96,00€2mg139,00€5mg227,00€10mg364,00€25mg600,00€50mg845,00€100mg1.121,00€1mL*10mM (DMSO)235,00€CDN1163
CAS:CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).Fórmula:C20H20N2O2Pureza:99.83% - ≥95%Cor e Forma:SolidPeso molecular:320.39Ref: TM-T7373
2mg42,00€5mg60,00€10mg87,00€25mg160,00€50mg250,00€100mg406,00€200mg592,00€1mL*10mM (DMSO)66,00€ABT-639
CAS:ABT-639 is a potent and selective T-type calcium channel blocker.Fórmula:C20H20ClF2N3O3SPureza:99.12% - 99.77%Cor e Forma:SolidPeso molecular:455.91Ref: TM-T3703
2mg35,00€5mg52,00€10mg80,00€25mg169,00€50mg283,00€100mg469,00€200mg682,00€1mL*10mM (DMSO)64,00€Ginsenoside Rf
CAS:Ginsenoside Rf (Panaxoside Rf) is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel.Fórmula:C42H72O14Pureza:99.82%Cor e Forma:SolidPeso molecular:801.01Praeruptorin C
CAS:<p>Praeruptorin C: an antioxidant, calcium antagonist, protects neurons, reduces vascular hypertrophy, affects cellular signals.</p>Fórmula:C24H28O7Pureza:99.6% - 99.92%Cor e Forma:SolidPeso molecular:428.47FPL64176
CAS:FPL64176 is a L-type calcium channels activator.Fórmula:C22H21NO3Pureza:98.68%Cor e Forma:SolidPeso molecular:347.41Ref: TM-T22788
1mg43,00€5mg88,00€10mg126,00€25mg264,00€50mg487,00€100mg710,00€200mg998,00€1mL*10mM (DMSO)70,00€ABT-639 hydrochloride
CAS:ABT-639 hydrochloride is a selective, novel T-type Ca2+ channel blocker.Fórmula:C20H21Cl2F2N3O3SCor e Forma:SolidPeso molecular:492.36Bepridil free base
CAS:Bepridil: Class IV anti-arrhythmic, calcium blocker, dilates coronary arteries.Fórmula:C24H34N2OCor e Forma:SolidPeso molecular:366.54Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFórmula:C26H44NNaO5SPureza:99.79% - 99.93%Cor e Forma:SolidPeso molecular:505.69Pinaverium bromide
CAS:Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain, diarrhea and intestinal discomfort.Fórmula:C26H41Br2NO4Pureza:99.52%Cor e Forma:White Crystalline PowderPeso molecular:591.42Ref: TM-T7603
10mg37,00€25mg52,00€50mg79,00€100mg103,00€200mg153,00€500mg249,00€1mL*10mM (DMSO)87,00€Thapsigargin
CAS:Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer.Fórmula:C34H50O12Pureza:99.07% - 99.3%Cor e Forma:Colourless FilmPeso molecular:650.75Fantofarone
CAS:Fantofarone (SR 33557) is a highly potent antagonist of Calcium Channel.Fórmula:C31H38N2O5SPureza:96.13% - 99.19%Cor e Forma:SolidPeso molecular:550.71OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Fórmula:C44H70O16Pureza:99.46% - ≥95%Cor e Forma:SolidPeso molecular:855.02Yangambin
CAS:Yangambin: selective PAF antagonist, hypotensive, inhibits Ca2+ influx, induces peripheral vasodilation, affects CNS.Fórmula:C24H30O8Pureza:98.02%Cor e Forma:SolidPeso molecular:446.49Mibefradil dihydrochloride
CAS:Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-typeFórmula:C29H40Cl2FN3O3Pureza:99.45% - 99.91%Cor e Forma:SolidPeso molecular:568.55Amlodipine mesylate
CAS:Amlodipine mesylate, an oral dihydropyridine Ca2+ blocker, treats angina, hypertension, and may be used in cancer research.Fórmula:C21H29ClN2O8SCor e Forma:SolidPeso molecular:504.98Norfluoxetine Hydrochloride
CAS:Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.Fórmula:C16H17ClF3NOPureza:99.71%Cor e Forma:SolidPeso molecular:331.761-Octanol
CAS:1-Octanol is a saturated fatty alcohol, inhibits T-type Ca²⁺ channels with a 4 μM IC50, and is a potential diesel-like biofuel.Fórmula:C8H18OPureza:99.94%Cor e Forma:Colourless LiquidPeso molecular:130.23Urolithin C
CAS:<p>Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.</p>Fórmula:C13H8O5Pureza:98.01% - 99.53%Cor e Forma:SolidPeso molecular:244.2Lomerizine
CAS:<p>Lomerizine, a blocker of diphenylmethylpiperazine Ca2+ channel, is used to prevent migraines.</p>Fórmula:C27H30F2N2O3Cor e Forma:SolidPeso molecular:468.54Ziconotide Acetate (107452-89-1 free base)
CAS:Ziconotide Acetate (Prialt, 107452-89-1) is an analgesic for neuropathic pain, acting on N-type calcium channels to block pain signals.Fórmula:C102H172N36O32S7Pureza:99.52% - 99.87%Cor e Forma:SolidPeso molecular:2639.2
