Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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Ionomycin calcium
CAS:<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Fórmula:C41H70CaO9Pureza:98% - 98.11%Cor e Forma:SolidPeso molecular:747.07ORM-10103
CAS:ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).ORM-10103 inhibited NCX currents with estimated IC50 values of 55 and 67 nMFórmula:C20H16N2O4Pureza:99.9%Cor e Forma:SolidPeso molecular:348.35Ref: TM-T12321
1mg43,00€5mg90,00€10mg135,00€25mg278,00€50mg445,00€100mg605,00€200mg817,00€1mL*10mM (DMSO)90,00€R-(-)-Niguldipine hydrochloride
CAS:R-(-)-Niguldipine HCl: L-type Ca2+ blocker, K+ agonist, α1A antagonist; lowers blood pressure; weaker enantiomer.Fórmula:C36H40ClN3O6Cor e Forma:SolidPeso molecular:646.17Falipamil
CAS:Produto Controlado<p>Applications Falipamil is a specific bradycardic agent and a calcium channel blocker.<br>References Boucher, M., et al.: Eur. J. Pharmacol., 306, 93 (1996), Mubagwa, K., et al.: Arch. Int. Pharmacodyn. Ther., 286, 71 (1987), Chaudhry, A., et al.: Development Cardiovascular Medicine, 46, 196 (1985), Ogiwara, Y., et al.: Jpn Heart J., 29, (1988)<br></p>Fórmula:C24H32N2O5Cor e Forma:NeatPeso molecular:428.52(S)-Lercanidipine Hydrochloride
CAS:Produto ControladoFórmula:C36H41N3O6·ClHCor e Forma:NeatPeso molecular:648.19Dihydrocinnamyl Cilnidipine
Produto Controlado<p>Applications Dihydrocinnamyl Cilnidipine is a metabolite of Cilnidipine (C441375); a dihydropyridine calcium channel blocker.<br>References Ikeda, K., et al.: Oyo Yakuri, 44, 433 (1992); Hosono, M., et al.: J. Pharmacobio-Dyn., 15, 547, (1992); Ishii, M.: Japan Pharmacol. Ther., 21, 59 (1993)<br></p>Fórmula:C27H30N2O7Cor e Forma:NeatPeso molecular:494.543-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine
Produto Controlado<p>Stability Light and Temperature Sensitive<br>Applications 3-Desethyl-3-(2-phthalimidoethyl) Phthaloyl Amlodipine is a derivative of Amlodipine (A633495); a dihydropyridine calcium channel blocker where activity mainly resides in the (-)-isomer.<br>References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995)<br></p>Fórmula:C36H30ClN3O9Cor e Forma:NeatPeso molecular:684.091(R)-Lercanidipine Hydrochloride
CAS:Produto ControladoFórmula:C36H41N3O6·ClHCor e Forma:NeatPeso molecular:648.19Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Fórmula:C16H17BrClN3O3Pureza:99.53%Cor e Forma:Off-White SolidPeso molecular:414.68Ref: TM-T6856
1mg37,00€5mg87,00€10mg123,00€25mg240,00€50mg363,00€100mg547,00€500mg1.198,00€1mL*10mM (DMSO)A consultarVerapamil
CAS:Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, and angina research.Fórmula:C27H38N2O4Pureza:99.61% - 99.93%Cor e Forma:OilPeso molecular:454.6Ref: TM-T20656
10mg35,00€25mg51,00€50mg73,00€100mg96,00€200mg143,00€500mg230,00€1mL*10mM (DMSO)55,00€Aladorian
CAS:Aladorian (ARM036), a benzothiazepine, has anti-arrhythmic properties for heart failure and CPVT research.Fórmula:C12H13NO4SPureza:98%Cor e Forma:SolidPeso molecular:267.3Aprindine hydrochloride
CAS:Aprindine HCl, a Class 1b antiarrhythmic, treats heart arrhythmias, outperforming digoxin in delaying atrial fibrillation. It's effective orally.Fórmula:C22H31ClN2Cor e Forma:SolidPeso molecular:358.95Levamlodipine gentisate
CAS:Levamlodipine gentisate, an active amlodipine enantiomer, is a dihydropyridine calcium channel blocker for treating hypertension and angina.Fórmula:C27H31ClN2O9Pureza:98%Cor e Forma:SolidPeso molecular:563Ethacrynate Sodium
CAS:Ethacrynate Sodium, a sodium salt, blocks chloride, potassium, and sodium transport mainly in Henle's loop.Fórmula:C13H12Cl2NaO4Pureza:98%Cor e Forma:SolidPeso molecular:326.12JTV-519 hemifumarate
CAS:JTV-519 hemifumarate: Ca2+ blocker, SERCA inhibitor, ryanodine receptor partial agonist; antiarrhythmic, cardioprotective.Fórmula:C54H68N4O8S2Pureza:98%Cor e Forma:SolidPeso molecular:965.28JTV-519
CAS:K201 (JTV-519) is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) byFórmula:C25H33ClN2O2SPureza:99.88%Cor e Forma:SolidPeso molecular:461.06Ref: TM-T24239
1mg60,00€5mg110,00€10mg155,00€25mg248,00€50mg365,00€100mg545,00€500mg1.188,00€1mL*10mM (DMSO)134,00€S-312-d
CAS:S-312d is a calcium channel antagonist. S-312-d can offer marked neuronal protective effects against ischemic injury.Fórmula:C20H22N2O4SPureza:98%Cor e Forma:SolidPeso molecular:386.46UK-52831
CAS:UK-52831, a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.Fórmula:C22H26Cl2N6O5Pureza:98%Cor e Forma:SolidPeso molecular:525.39Niguldipine Free Base
CAS:<p>Niguldipine Free Base is a calcium channel blocker and a₁-adrenergic receptor antagonist and a clinical modulator of multidrug resistance.</p>Fórmula:C36H39N3O6Pureza:98.97%Cor e Forma:SolidPeso molecular:609.71
