Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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BBT
CAS:BBT has anti-hyperglycemic activity, protecting beta cells from cytokine or streptozotocin-induced cell death, and restoring beta cell function.Fórmula:C18H12BrNO2SPureza:99.02%Cor e Forma:SolidPeso molecular:386.26TMDJ-035
CAS:TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2).Fórmula:C16H12F3N5OPureza:98%Cor e Forma:SolidPeso molecular:347.29Mioflazine hydrochloride
CAS:Mioflazine hydrochloride is a nucleoside transport inhibitor that acts on adenosine to improve sleep.Fórmula:C29H34Cl4F2N4O3Cor e Forma:SolidPeso molecular:666.41Budiodarone
CAS:Budiodarone (ATI-2042) resembles amiodarone, potentially preventing atrial fibrillation.Fórmula:C27H31I2NO5Cor e Forma:SolidPeso molecular:703.35Reldesemtiv
CAS:<p>Reldesemtiv (CK-2127107) boosts exercise capacity, targeting fast muscle troponin, EC50 3.4 μM.</p>Fórmula:C19H18F2N6OPureza:97.27%Cor e Forma:SolidPeso molecular:384.38Cis-22a
CAS:Cis-22a: selective TRPV6 inhibitor (IC50=0.32μM), halts T47D breast cancer cell growth.Fórmula:C24H30F3N3O2Pureza:99.99%Cor e Forma:SolidPeso molecular:449.51AY 77
CAS:<p>AY 77: Potent, selective PAR2 agonist, favors Ca2+ (ec50=40nM) & ERK1/2 (ec50=2μM), boosts breast cancer cell migration.</p>Fórmula:C21H32N4O4Pureza:99.7%Cor e Forma:SolidPeso molecular:404.5Calcium channel-modulator-1
CAS:<p>Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.</p>Fórmula:C26H24Cl2N2O7SPureza:99.95%Cor e Forma:SolidPeso molecular:579.45Bupivacaine hydrochloride monohydrate
CAS:Bupivacaine hydrochloride monohydrate is an NMDA receptor inhibitor that inhibits SCN5A channels and is commonly used in the study of chronic pain.Fórmula:C18H31ClN2O2Pureza:99.91%Cor e Forma:SolidPeso molecular:342.9EMD57033
CAS:EMD57033 activates cardiac troponin C, enhances Ca2+ sensitivity to boost heart contraction.Fórmula:C22H23N3O4SPureza:97.24% - 99.11%Cor e Forma:SolidPeso molecular:425.5Fluspirilene
CAS:Fluspirilene is a long-acting antipsychotic for schizophrenia, inhibiting L-type calcium channels (IC50: 0.03 μM).Fórmula:C29H31F2N3OPureza:99.59%Cor e Forma:SolidPeso molecular:475.57Cav 2.2/3.2 blocker 1
Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM & 80 μM, respectively; penetrates CNS.Fórmula:C28H30N2O3Cor e Forma:SolidPeso molecular:442.55NNC 55-0396
CAS:<p>NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.</p>Fórmula:C30H40Cl2FN3O2Pureza:99.00%Cor e Forma:SolidPeso molecular:564.56SB-423557
CAS:SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nMFórmula:C28H36N2O4Pureza:98%Cor e Forma:SolidPeso molecular:464.60Cav 3.2 inhibitor 2
Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.Fórmula:C32H37F2N3OCor e Forma:SolidPeso molecular:517.65Cav 3.2 inhibitor 1
Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.Fórmula:C32H39N3OCor e Forma:SolidPeso molecular:481.67IAB15
CAS:IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Fórmula:C15H14F3NO2Cor e Forma:SolidPeso molecular:297.27RWJ 22108
CAS:RWJ 22108 is a bronchial-selective calcium channel (calcium channel) blocker that exhibits an IC50 of 5.7 nM in dog bronchial smooth muscle calcium-dependent contractions.Fórmula:C27H30ClFN2O4SCor e Forma:SolidPeso molecular:533.06CCR4 antagonist 2
CAS:CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits TregFórmula:C26H28Cl2N6OPureza:98%Cor e Forma:SolidPeso molecular:511.45PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Fórmula:C33H33N3O4Cor e Forma:SolidPeso molecular:535.63
