Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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NAADP tetrasodium salt
CAS:Ca2+ mobilizing agentFórmula:C21H27N6O18P3Pureza:98%Cor e Forma:SolidPeso molecular:744.39D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
CAS:Ins(1,3,4,5)-P4, made via Ins(1,4,5)P3 phosphorylation, boosts calcium by opening ER and plasma membrane channels.Fórmula:C6H8Na8O18P4Cor e Forma:SolidPeso molecular:675.93Huwentoxin I
CAS:Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.Fórmula:C161H246N48O44S6Pureza:98%Cor e Forma:SolidPeso molecular:3750.36Cavα2δ-IN-1
CAS:Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a KiFórmula:C18H27N5OCor e Forma:SolidPeso molecular:329.448Flosatidil
CAS:Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,Fórmula:C26H34F3N3O3SPureza:99.87% - 99.99%Cor e Forma:SolidPeso molecular:525.6317R(18S)-EpETE
CAS:17R(18S)-EpETE: Oxylipin, eicosapentaenoic acid metabolite, activates BKCa channels, has negative chronotropic effects.Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.457ILS-920
CAS:ILS-920, a Rapamycin analog, has reduced immunosuppression, enhanced neuroprotection, and preferentially binds FKBP52 and L-type VGCC β1.Fórmula:C57H86N2O14Pureza:98%Cor e Forma:SolidPeso molecular:1023.3G-Glu-Ser
CAS:G-Glu-Ser is a calcium receptor activator and Flavor-enriching agent.Fórmula:C8H14N2O6Cor e Forma:SolidPeso molecular:234.21Flunarizine
CAS:Flunarizine is an orally administered peripheral vasodilator, a dual blocker of voltage-gated Na+/Ca2+ channels and a D2 dopamine receptor antagonist.Fórmula:C26H26F2N2Pureza:99.9%Cor e Forma:SolidPeso molecular:404.50BTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Fórmula:C34H28N4O4Pureza:98.34%Cor e Forma:SolidPeso molecular:556.61Chlorocresol
CAS:Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Fórmula:C7H7ClOCor e Forma:SolidPeso molecular:142.58Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS:ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.Fórmula:C12H10ClNO3Pureza:99.17%Cor e Forma:SolidPeso molecular:251.67Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Fórmula:C20H25ClN2O5·C6H6O3SH2OCor e Forma:SolidPeso molecular:1224.18Elgodipine
CAS:Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.Fórmula:C29H33FN2O6Pureza:99.84% - 99.98%Cor e Forma:SolidPeso molecular:524.58Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Fórmula:C153H266N38O38S2Cor e Forma:SolidPeso molecular:3310.11Triphenylethylene
CAS:<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C20H16Cor e Forma:White PowderPeso molecular:256.34ω-Agatoxin TK
CAS:<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Fórmula:C215H337N65O70S10Pureza:98%Cor e Forma:SolidPeso molecular:5273.02(±)5(6)-DiHETE
CAS:Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.472Lyso-Globotriaosylceramide (d18:1)
CAS:Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.Fórmula:C36H67NO17Cor e Forma:SolidPeso molecular:785.922ProTx-I
CAS:<p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>Fórmula:C171H245N53O47S6Pureza:98%Cor e Forma:SolidPeso molecular:3987.51
