Canais de Cálcio
Os canais de cálcio são proteínas de membrana que regulam o fluxo de íons de cálcio para dentro e fora das células, o que é essencial para várias funções celulares, incluindo a contração muscular, a liberação de neurotransmissores e a expressão gênica. A desregulação da atividade dos canais de cálcio está associada a condições como hipertensão, arritmias cardíacas e distúrbios neurológicos. Na CymitQuimica, oferecemos uma ampla seleção de moduladores de canais de cálcio para apoiar sua pesquisa em saúde cardiovascular, neurobiologia e transdução de sinais.
Foram encontrados 541 produtos de "Canais de Cálcio"
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Mipsagargin
CAS:Mipsagargin (G-202) is a new antibiotic that inhibits DNA biosynthesis.Fórmula:C66H100N6O27Pureza:98%Cor e Forma:SolidPeso molecular:1409.52Cavα2δ-IN-1
CAS:Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a KiFórmula:C18H27N5OCor e Forma:SolidPeso molecular:329.448MMK 1
CAS:Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Fórmula:C75H123N19O18SPureza:98%Cor e Forma:SolidPeso molecular:1610.97Flosatidil
CAS:Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,Fórmula:C26H34F3N3O3SPureza:99.87% - 99.99%Cor e Forma:SolidPeso molecular:525.63ProTx-I
CAS:<p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>Fórmula:C171H245N53O47S6Pureza:98%Cor e Forma:SolidPeso molecular:3987.51Lyso-Globotriaosylceramide (d18:1)
CAS:Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.Fórmula:C36H67NO17Cor e Forma:SolidPeso molecular:785.922Sulcardine 2HCl
CAS:Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Fórmula:C24H35Cl2N3O4SPureza:99.33% - 99.76%Cor e Forma:SoildPeso molecular:532.523ω-Conotoxin MVIIC
CAS:Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.Fórmula:C106H178N40O32S7Pureza:98%Cor e Forma:White Lyophilised SolidPeso molecular:2749NAADP tetrasodium salt
CAS:Ca2+ mobilizing agentFórmula:C21H27N6O18P3Pureza:98%Cor e Forma:SolidPeso molecular:744.39Triphenylethylene
CAS:<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C20H16Cor e Forma:White PowderPeso molecular:256.34DMNPE-4 AM-caged-calcium
CAS:DMNPE-4 AM is an EGTA analogue, Ca2+-selective, with Kd 48 nM (pH 7.2) and 19 nM (pH 7.4). Photolysis reduces its Ca2+ affinity to ~2 nM.Fórmula:C34H47N3O22Cor e Forma:SolidPeso molecular:849.749OPC 8490 free base
CAS:OPC 8490 free base is a positive inotropic vasodilator and a cardiotonic agent that can be used to study cardiovascular diseases.Fórmula:C24H27N3O3Pureza:99.53%Cor e Forma:SoildPeso molecular:405.49PACAP-38 (31-38), human, mouse, rat TFA
PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.Fórmula:C49H84F3N17O13Pureza:98%Cor e Forma:SolidPeso molecular:1176.29Nesiritide acetate
CAS:Nesiritide, a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide, enhances vasorelaxation ex vivo in porcine hearts from an acute coronary occlusion model when given as a 2 µg/kg bolus dose followed by a 0.01 µg/kg per minute infusion, facilitated by the calcium ionophore A23187. Formulations containing nesiritide have been utilized in managing congestive heart failure.Fórmula:C143H244N50O42S4C2H4O2Cor e Forma:SolidPeso molecular:3524.1LY393615
LY393615 (NCC1048) is a novel blocker of both neuronal Ca²⁺ (calcium) and Na⁺ (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC₅₀) of 1.9Pureza:98%Cor e Forma:Odour SolidsFTX-3.3
CAS:sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.Fórmula:C12H29N7OCor e Forma:SolidPeso molecular:287.412β-Cyfluthrin
CAS:β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products.Fórmula:C22H18Cl2FNO3Cor e Forma:SolidPeso molecular:434.29(S)-Lercanidipine D3 hydrochloride
CAS:(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:651.21Magnesium sulfate
CAS:Magnesium sulfate: anticonvulsant for eclampsia, tocolytic agent.Fórmula:MgSO4Pureza:98%Cor e Forma:SolidPeso molecular:120.37(R)-Nicardipine
CAS:(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Fórmula:C26H29N3O6Cor e Forma:SolidPeso molecular:479.53
