Receptor GABA
Os receptores de GABA são os principais receptores de neurotransmissores inibitórios no sistema nervoso central, desempenhando um papel crítico na regulação da excitabilidade neuronal e na manutenção do equilíbrio entre excitação e inibição. A disfunção dos receptores de GABA está implicada em vários distúrbios neurológicos e psiquiátricos, incluindo epilepsia, ansiedade e depressão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de GABA para apoiar sua pesquisa em neurobiologia, saúde mental e desenvolvimento terapêutico.
Foram encontrados 367 produtos para "Receptor GABA".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Fórmula:C18H22O2Cor e Forma:SolidPeso molecular:270.37(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Fórmula:C6H11NO2Cor e Forma:SolidPeso molecular:129.16Riluzole-13C,15N2
CAS:Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.Fórmula:CC7H5F3OS15N2Cor e Forma:SolidPeso molecular:237.18Furosemide
CAS:Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.Fórmula:C12H11ClN2O5SPureza:99.32% - 99.89%Cor e Forma:White SolidPeso molecular:330.744Endosulfan I
CAS:Produto ControladoEndosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complexFórmula:C9H6Cl6O3SPureza:99.86%Cor e Forma:White SolidPeso molecular:406.93FGIN-1-43
CAS:FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.Fórmula:C28H36Cl2N2OPureza:99.57%Cor e Forma:SolidPeso molecular:487.53-Aminopropylphosphonic Acid
CAS:3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand bindingFórmula:C3H10NO3PPureza:99.84%Cor e Forma:SolidPeso molecular:139.09(Iso)-Atagabalin HCl
CAS:(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.Fórmula:C10H20ClNO2Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:221.72Fipronil sulfone
CAS:Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Fórmula:C12H4Cl2F6N4O2SPureza:98%Cor e Forma:SolidPeso molecular:453.1412,14-Dichlorodehydroabietic acid
CAS:12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Fórmula:C20H26Cl2O2Cor e Forma:SolidPeso molecular:369.33MIDD0301
CAS:MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.Fórmula:C19H13BrFN3O2Pureza:98%Cor e Forma:SolidPeso molecular:414.23Emamectin B1a
CAS:Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.Fórmula:C49H75NO13Cor e Forma:SolidPeso molecular:886.133GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Fórmula:C15H17BrO4SCor e Forma:SolidPeso molecular:373.26Chrodrimanin B
CAS:Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Fórmula:C27H32O8Cor e Forma:SolidPeso molecular:484.545DAA-1106
CAS:DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Fórmula:C23H22FNO4Pureza:99.54%Cor e Forma:SolidPeso molecular:395.42Flufiprole
CAS:Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.Fórmula:C16H10Cl2F6N4OSCor e Forma:SolidPeso molecular:491.24Afizagabar
CAS:Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.Fórmula:C19H12FN3O2SCor e Forma:SolidPeso molecular:365.38Atagabalin
CAS:Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Fórmula:C10H19NO2Cor e Forma:SolidPeso molecular:185.26Sandaracopimaric acid
CAS:Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Fórmula:C20H30O2Cor e Forma:SolidPeso molecular:302.45GABAB receptor antagonist 5
GABAB receptor antagonist 5 (Compound 23) is a competitive antagonist of the GABAB receptor. It holds potential for research into neuropsychiatric disorders, including epilepsy, depression, and addiction.Cor e Forma:Odour Solid
