Glucoquinase
A glucocinase (GK) é uma enzima que catalisa a fosforilação da glicose em glicose-6-fosfato, um passo crítico na glicólise. A GK é predominantemente expressa no fígado e no pâncreas, onde desempenha um papel fundamental na regulação dos níveis de glicose no sangue. Inibidores de GK são de grande interesse no estudo de distúrbios metabólicos como o diabetes, pois podem modular o metabolismo da glicose e a secreção de insulina. Na CymitQuimica, oferecemos inibidores de glucocinase para apoiar sua pesquisa em diabetes, metabolismo e desenvolvimento terapêutico.
Foram encontrados 53 produtos de "Glucoquinase"
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AR453588 hydrochloride
CAS:<p>AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.</p>Fórmula:C25H26ClN7O2S2Pureza:98%Cor e Forma:SolidPeso molecular:556.1CM-10-18
CAS:<p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>Fórmula:C17H35NO5Cor e Forma:SolidPeso molecular:333.46PF-04937319
CAS:<p>PF-04937319 activates glucokinase (EC50=154.4μM) with low hypoglycemia risk, researched for type 2 diabetes treatment.</p>Fórmula:C22H20N6O4Pureza:99.89%Cor e Forma:SolidPeso molecular:432.43AZD-1656
CAS:<p>AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2</p>Fórmula:C24H26N6O5Pureza:97.07% - 99.37%Cor e Forma:SolidPeso molecular:478.5AZD1092
CAS:<p>AZD1092 is the glucokinase enzyme activator.</p>Fórmula:C24H26N4O5Pureza:98%Cor e Forma:SolidPeso molecular:450.49WAY-297848
CAS:<p>WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome.</p>Fórmula:C13H13ClN2O2SPureza:98.19%Cor e Forma:SolidPeso molecular:296.77Glucokinase activator 7
CAS:<p>Glucokinase activator7 is an activator of glucose kinase (Glucokinase) and can be utilized in research on diabetes and hyperglycemia [refer to compound on page 176].</p>Fórmula:C14H13N3O2SCor e Forma:SolidPeso molecular:287.337GKA50 quarterhydrate
<p>GKA50 quarterhydrate: glucokinase activator, EC50 of 33 nM, boosts insulin, cuts glucose in rats.</p>Fórmula:C26H30N2O7Cor e Forma:SolidPeso molecular:469.01Gcase activator 2
CAS:<p>Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase, increases lysosomal substrate metabolism.</p>Fórmula:C21H24N4O2Pureza:99.51% - 99.76%Cor e Forma:SolidPeso molecular:364.44Glucokinase activator 8
CAS:<p>Glucokinase activator8 is an activator of glucose kinase (glucokinase).</p>Fórmula:C14H13N3O2SCor e Forma:SolidPeso molecular:287.337MK-0941
CAS:<p>MK-0941 is an orally active and allosteric glucokinase activator, has potential in the treatment of type 2 diabetes.</p>Fórmula:C22H28N4O9S2Cor e Forma:SolidPeso molecular:556.61Hex
CAS:<p>Hex is a potent inhibitor of enolase, exhibiting inhibitory activity with Ki values of 74.4 nM and 269.4 nM against ENO2 and ENO1, respectively.</p>Fórmula:C5H10NO5PCor e Forma:SolidPeso molecular:195.11GKA50
CAS:<p>GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose).</p>Fórmula:C26H28N2O6Pureza:98%Cor e Forma:SolidPeso molecular:464.51
