Caseína quinase
As caseína quinases são uma família de proteínas quinases serina/treonina que regulam vários processos celulares, incluindo a reparação do DNA, os ritmos circadianos e a transdução de sinais. Essas quinases estão envolvidas na fosforilação de numerosas proteínas e estão implicadas em doenças como o câncer, distúrbios neurodegenerativos e síndromes metabólicas. Na CymitQuimica, oferecemos uma seleção de inibidores de caseína quinase para apoiar sua pesquisa em transdução de sinais, regulação do ciclo celular e desenvolvimento terapêutico.
Foram encontrados 130 produtos de "Caseína quinase"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
HDAC/CK2-IN-1
CAS:<p>HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.</p>Fórmula:C15H18Br4N4O2Cor e Forma:SolidPeso molecular:605.95CK2-IN-4
CAS:<p>CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.</p>Fórmula:C18H11N3O4SPureza:99.72%Cor e Forma:SolidPeso molecular:365.36CK2α-IN-1
CAS:<p>CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can</p>Fórmula:C16H11N3O4SPureza:98%Cor e Forma:SolidPeso molecular:341.34CK1-IN-2
CAS:<p>CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.</p>Fórmula:C17H12FN3O2Pureza:99.31%Cor e Forma:SolidPeso molecular:309.29PI-828
CAS:<p>PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.</p>Fórmula:C19H18N2O3Pureza:99.95%Cor e Forma:SolidPeso molecular:322.36XL413 xHCl
CAS:<p>BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215</p>Fórmula:C14H12ClN3O2·xHClPureza:99.37% - 99.67%Cor e Forma:SolidPeso molecular:326.18BioE-1115
CAS:<p>BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).</p>Fórmula:C19H18FN3O2Pureza:97.54%Cor e Forma:SolidPeso molecular:339.36Casein kinase 1δ-IN-1
CAS:<p>Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ.</p>Fórmula:C11H7N3OSPureza:99.46%Cor e Forma:SolidPeso molecular:229.26Ac-VDVAD-CHO
CAS:<p>Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].</p>Fórmula:C23H37N5O10Pureza:98%Cor e Forma:SolidPeso molecular:543.57ON 108600
CAS:<p>ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.</p>Fórmula:C22H14Cl2N2O6S2Pureza:98%Cor e Forma:SolidPeso molecular:537.39Casein kinase 1δ-IN-5
CAS:<p>Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects in</p>Fórmula:C16H11F3N2OSPureza:98%Cor e Forma:SolidPeso molecular:336.33Casein kinase 1δ-IN-10
CAS:<p>Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).</p>Fórmula:C21H17N3O3Pureza:98%Cor e Forma:SolidPeso molecular:359.38TID43
CAS:<p>TID43, a CK2 inhibitor, exhibits potent inhibition with an IC50 value of 0.3 μM. It is applicable in anti-angiogenic research [1].</p>Fórmula:C10H3I4NO4Cor e Forma:SolidPeso molecular:708.755XL413 hydrochloride
CAS:<p>XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 hydrochloride also inhibits CK2 and PIM1.</p>Fórmula:C14H13Cl2N3O2Pureza:98.81% - 99.8%Cor e Forma:SolidPeso molecular:326.18Casein kinase 1δ-IN-4
CAS:<p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>Fórmula:C16H12N6SPureza:98%Cor e Forma:SolidPeso molecular:320.37Casein Kinase II Inhibitor IV
CAS:<p>Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.</p>Fórmula:C24H23N5O3Pureza:99.65% - 99.75%Cor e Forma:SolidPeso molecular:429.47Casein kinase 1δ-IN-13
CAS:Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.Fórmula:C15H13N3O2SCor e Forma:SolidPeso molecular:299.35Casein kinase 1δ-IN-28
CAS:<p>Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.</p>Fórmula:C23H23FN6Cor e Forma:SolidPeso molecular:402.467CK1δ-IN-6
CAS:<p>CK1δ-IN-6 (Compound 303) is an inhibitor of Casein kinase 1δ, with potential applications in Alzheimer's disease research.</p>Fórmula:C23H17N3O4Cor e Forma:SolidPeso molecular:399.399WAY-606344
CAS:<p>WAY-606344 (Compound 97) is an inhibitor of Casein kinase 1δ and shows potential for Alzheimer's disease research.</p>Fórmula:C14H8ClN3O2Cor e Forma:SolidPeso molecular:285.685
